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muscarinic acetylcholine receptor M5 [Homo sa.. [gi:20373106] - Target BioActivity Data
Also known as: muscarinic acetylcholine receptor M5 [Homo sapiens].
Filters: All Data » Active      
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BioActivity Outcomes:
Probe(4)
 
 
Active(118)
 
 
BioAssay Types:
Screening(76)
 
 
Confirmatory(31)
 
 
 
BioActivity Types:
EC50(26)
 
 
 
IC50(5)
 
 
 
Substance Types:
Chemical(122)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 122   Total Pages: 7   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID164186823]
[CID42519285]
Average_IC50_uM 0.44Discovery of Novel Antagonists of Muscarinic Receptor M5: CRC Assay [AID743110, Type: confirmatory]
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2
[SID137294184]
[CID57525860]
Average_EC50_uM 0.55Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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3
[SID137294184]
[CID57525860]
Average_EC50_uM_hM5 0.589Discovery of Selective Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor (M5) in CHO cells expressing human M5 receptor [AID651927, Type: confirmatory]
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4
[SID137294184]
[CID57525860]
ML326 M5 PAM Competition in Radioligand Binding assays (Eurofins PanLabs) [AID651832, Type: other]
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5
[SID92845376]
[CID45281794]
Cmpd EC50 5.71e-12Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
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6
[SID92845379]
[CID45281797]
Cmpd EC50 6.06e-12Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
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7
[SID85285486]
[CID42633508]
Cmpd EC50 3.68e-05Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
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8
[SID85285486]
[CID42633508]
EC50_uM 0.21Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: [3H]N-methylscopolamine Competition with Acetylcholine [AID2194, Type: confirmatory]
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9
[SID137294201]
[CID57525868]
Average_EC50_uM 0.36Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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10
[SID137294188]
[CID57525847]
Average_EC50_uM 0.52Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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11
[SID164186701]
[CID24791252]
Average_IC50_uM 1.16Discovery of Novel Antagonists of Muscarinic Receptor M5: CRC Assay [AID743110, Type: confirmatory]
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12
[SID85285486]
[CID42633508]
M5 EC50 1.161Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
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13
[SID137294174]
[CID57525867]
Average_EC50_uM 1.38Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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14
[SID137294200]
[CID57525831]
Average_EC50_uM 1.45Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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15
[SID87352032]
[CID44602489]
M5 EC50 1.918Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
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16
[SID137294187]
[CID57525838]
Average_EC50_uM 1.97Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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17
[SID137294171]
[CID57525866]
Average_EC50_uM 2.19Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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18
[SID92845390]
[CID45281808]
M5 EC50 2.653Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
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19
[SID92845376]
[CID45281794]
M5 EC50 2.662Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
20
[SID92845379]
[CID45281797]
M5 EC50 2.769Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
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