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muscarinic acetylcholine receptor M5 [Homo sa.. [gi:20373106] - Target BioActivity Data
Also known as: muscarinic acetylcholine receptor M5 [Homo sapiens].
Filters: All Data » Active      
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BioActivity Outcomes:
Probe(3)
 
 
Active(110)
 
 
BioAssay Types:
Screening(72)
 
 
Confirmatory(26)
 
 
 
BioActivity Types:
EC50(26)
 
 
 
Substance Types:
Chemical(113)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 113   Total Pages: 3   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID137294184]
[CID57525860]
Average_EC50_uM 0.55Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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2
[SID137294184]
[CID57525860]
Average_EC50_uM_hM5 0.589Discovery of Selective Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor (M5) in CHO cells expressing human M5 receptor [AID651927, Type: confirmatory]
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3
[SID137294184]
[CID57525860]
ML326 M5 PAM Competition in Radioligand Binding assays (Eurofins PanLabs) [AID651832, Type: other]
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4
[SID92845376]
[CID45281794]
Cmpd EC50 5.71e-12Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
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5
[SID92845379]
[CID45281797]
Cmpd EC50 6.06e-12Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
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6
[SID85285486]
[CID42633508]
Cmpd EC50 3.68e-05Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
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7
[SID85285486]
[CID42633508]
EC50_uM 0.21Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: [3H]N-methylscopolamine Competition with Acetylcholine [AID2194, Type: confirmatory]
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8
[SID137294201]
[CID57525868]
Average_EC50_uM 0.36Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
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9
[SID137294188]
[CID57525847]
Average_EC50_uM 0.52Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
10
[SID85285486]
[CID42633508]
M5 EC50 1.161Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
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11
[SID137294174]
[CID57525867]
Average_EC50_uM 1.38Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
12
[SID137294200]
[CID57525831]
Average_EC50_uM 1.45Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
13
[SID87352032]
[CID44602489]
M5 EC50 1.918Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
14
[SID137294187]
[CID57525838]
Average_EC50_uM 1.97Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
15
[SID137294171]
[CID57525866]
Average_EC50_uM 2.19Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
16
[SID92845390]
[CID45281808]
M5 EC50 2.653Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
17
[SID92845376]
[CID45281794]
M5 EC50 2.662Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
18
[SID92845379]
[CID45281797]
M5 EC50 2.769Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
19
[SID92845385]
[CID45281803]
M5 EC50 3.257Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
20
[SID92845383]
[CID45281801]
M5 EC50 3.589Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
21
[SID92845378]
[CID45281796]
M5 EC50 3.859Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
22
[SID85285464]
[CID3008304]
M5 EC50 4.079Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
23
[SID92845380]
[CID45281798]
M5 EC50 4.835Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
24
[SID92845389]
[CID45281807]
M5 EC50 5.679Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay [AID2204, Type: confirmatory]
View
25
[SID137294184]
[CID57525860]
Average_EC50_uM 51.6Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: Fold-shift Assay [AID651776, Type: confirmatory]
View
26
[SID137294177]
[CID57525846]
Average_EC50_uM Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
27
[SID137294173]
[CID57525853]
Average_EC50_uM Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
28
[SID92845385]
[CID45281803]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
29
[SID92845387]
[CID45281805]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
30
[SID92845388]
[CID45281806]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
31
[SID92845380]
[CID45281798]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
32
[SID92845381]
[CID45281799]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
33
[SID92845382]
[CID45281800]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
34
[SID92845383]
[CID45281801]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
35
[SID92845384]
[CID45281802]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
36
[SID92845379]
[CID45281797]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
37
[SID92845378]
[CID45281796]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
38
[SID85285486]
[CID42633508]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: PAM SAR with Muscarinic M5 [AID2198, Type: other]
View
39
[SID92845376]
[CID45281794]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
40
[SID92845377]
[CID45281795]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
41
[SID85285466]
[CID2048702]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
42
[SID85285467]
[CID28492826]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
43
[SID85285468]
[CID7677100]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
44
[SID85285469]
[CID44157160]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: PAM SAR with Muscarinic M5 [AID2198, Type: other]
View
45
[SID85285469]
[CID44157160]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
46
[SID85285470]
[CID44157161]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
47
[SID85285471]
[CID44157162]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
48
[SID85285475]
[CID44157239]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
49
[SID85285476]
[CID44157240]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: SAR with Acetylcholine [AID2665, Type: screening]
View
50
[SID85285477]
[CID44157241]
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: PAM SAR with Muscarinic M5 [AID2198, Type: other]
View