Bookmark and Share
muscarinic acetylcholine receptor M5 [Homo sa.. [gi:20373106] - Target BioActivity Data
Also known as: muscarinic acetylcholine receptor M5 [Homo sapiens].
Filters: All Data » Active      
Filter selected
BioActivity Outcomes:
Probe(7)
 
 
Active(288)
 
 
BioAssay Types:
Screening(171)
 
 
 
Confirmatory(109)
 
 
 
BioActivity Types:
EC50(72)
 
 
 
IC50(37)
 
 
 
Substance Types:
Chemical(295)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 295   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID164186717]
[CID71737672]
Average_EC50_uM 0.23Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Confirmatory Assay [AID743102, Type: confirmatory]
View
2
[SID163678873]
[CID71598521]
Average_IC50_uM 0.3Discovery of Novel Negative Allosteric Modulators (NAM) of Muscarinic Receptor M5: CRC Assay [AID743026, Type: confirmatory]
View
3
[SID164186823]
[CID42519285]
Average_IC50_uM 0.44Discovery of Novel Antagonists of Muscarinic Receptor M5: CRC Assay [AID743110, Type: confirmatory]
View
4
[SID137294184]
[CID57525860]
Average_EC50_uM 0.55Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
5
[SID137294184]
[CID57525860]
Average_EC50_uM_hM5 0.589Discovery of Selective Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor (M5) in CHO cells expressing human M5 receptor [AID651927, Type: confirmatory]
View
6
[SID137294184]
[CID57525860]
ML326 M5 PAM Competition in Radioligand Binding assays (Eurofins PanLabs) [AID651832, Type: other]
View
7
[SID164186717]
[CID71737672]
Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Single Point Assay [AID743100, Type: screening]
View
8
[SID92845376]
[CID45281794]
Cmpd EC50 5.71e-12Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
View
9
[SID92845379]
[CID45281797]
Cmpd EC50 6.06e-12Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
View
10
[SID85285486]
[CID42633508]
Cmpd EC50 3.68e-05Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay [AID2186, Type: confirmatory]
View
11
[SID164351726]
[CID71771058]
Average_EC50_uM 0.16Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Confirmatory Assay [AID743102, Type: confirmatory]
View
12
[SID85285486]
[CID42633508]
EC50_uM 0.21Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: [3H]N-methylscopolamine Competition with Acetylcholine [AID2194, Type: confirmatory]
View
13
[SID164186754]
[CID71737709]
Average_EC50_uM 0.34Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Confirmatory Assay [AID743102, Type: confirmatory]
View
14
[SID137294201]
[CID57525868]
Average_EC50_uM 0.36Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
15
[SID164186692]
[CID71737648]
Average_EC50_uM 0.42Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Confirmatory Assay [AID743102, Type: confirmatory]
View
16
[SID164186737]
[CID71737692]
Average_EC50_uM 0.43Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Confirmatory Assay [AID743102, Type: confirmatory]
View
17
[SID164186720]
[CID71737675]
Average_EC50_uM 0.43Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Confirmatory Assay [AID743102, Type: confirmatory]
View
18
[SID163679215]
[CID71598549]
Average_IC50_uM 0.48Discovery of Novel Negative Allosteric Modulators (NAM) of Muscarinic Receptor M5: CRC Assay [AID743026, Type: confirmatory]
View
19
[SID137294188]
[CID57525847]
Average_EC50_uM 0.52Discovery of Novel Positive Allosteric Modulators (PAM) of the Muscarinic Receptor M5: CRC Assay [AID651878, Type: confirmatory]
View
20
[SID164186665]
[CID71737621]
Average_EC50_uM 0.53Discovery of Novel Positive Allosteric Modulators (PAMs) of Muscarinic Receptor M5: Confirmatory Assay [AID743102, Type: confirmatory]
View