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Lysosomal protective protein; Carboxypeptidas.. [gi:20178316] - Target BioActivity Data
Also known as: Lysosomal protective protein; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; Protective protein cathepsin A; PPCA; Protective protein for beta-galactosidase; Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain.
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BioActivity Outcomes:
Active(34)
 
 
BioAssay Types:
Literature(34)
 
 
BioActivity Types:
IC50(34)
 
 
Substance Types:
Chemical(34)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2    Data Row: 34   Total Pages: 1   
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID163324453]
[CID67362073]
IC50 0.003Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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2
[SID163331450]
[CID60182323]
IC50 0.005Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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3
[SID163331451]
[CID67362057]
IC50 0.01Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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4
[SID163324455]
[CID71455231]
IC50 0.015Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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5
[SID163314180]
[CID71449876]
IC50 0.015Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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6
[SID163338328]
[CID71462414]
IC50 0.025Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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7
[SID163327916]
[CID53308743]
IC50 0.026Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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8
[SID163334934]
[CID71460700]
IC50 0.03Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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9
[SID163324456]
[CID60182322]
IC50 0.038Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
10
[SID163324454]
[CID67362517]
IC50 0.05Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
11
[SID163338329]
[CID71462415]
IC50 0.057Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
12
[SID163317621]
[CID71451692]
IC50 0.059Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
13
[SID163338326]
[CID71462412]
IC50 0.06Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
14
[SID163327915]
[CID67362514]
IC50 0.07Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
15
[SID163317620]
[CID71451691]
IC50 0.07Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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16
[SID163334935]
[CID71460701]
IC50 0.076Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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17
[SID163314208]
[CID71449892]
IC50 0.087Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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18
[SID163324457]
[CID71455232]
IC50 0.1Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
19
[SID163338327]
[CID71462413]
IC50 0.1Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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20
[SID163317651]
[CID71451708]
IC50 0.102Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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21
[SID163331452]
[CID71458887]
IC50 0.11Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
22
[SID163331453]
[CID71458888]
IC50 0.11Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
23
[SID163321114]
[CID71453540]
IC50 0.12Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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24
[SID163314209]
[CID71449893]
IC50 0.2Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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25
[SID163317652]
[CID71451709]
IC50 0.226Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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26
[SID163334958]
[CID71460713]
IC50 0.252Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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27
[SID163338323]
[CID71462409]
IC50 0.274Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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28
[SID163338324]
[CID71462410]
IC50 0.357Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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29
[SID163331449]
[CID71458886]
IC50 0.375Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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30
[SID103193574]
[CID1609]
IC50 0.6Inhibition of recombinant CatA using [14C]GS-7340 substrate [AID279732, Type: Literature]
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31
[SID163338325]
[CID71462411]
IC50 0.803Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
View
32
[SID163334932]
[CID71460698]
IC50 5.38Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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33
[SID163327914]
[CID71457028]
IC50 7.8Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substrate incubated for 15 mins prior to substrate addition measured after 15 mins by fluorimetric analysis [AID702511, Type: Literature]
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34
[SID103274564]
[CID5936]
IC50 10Inhibition of recombinant CatA using [14C]GS-7340 substrate [AID279732, Type: Literature]
View