Bookmark and Share
Tumor necrosis factor; Cachectin; TNF-alpha;.. [gi:135934] - Target BioActivity Data
Also known as: Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Tumor necrosis factor, membrane form; N-terminal fragment; NTF; Intracellular domain 1; ICD1; Intracellular domain 2; ICD2; C-domain 1; C-domain 2; Tumor necrosis factor, soluble form.
Filters: All Data » Active      
Filter selected
BioActivity Outcomes:
Active(33)
 
 
BioAssay Types:
Literature(18)
 
 
Confirmatory(11)
 
 
BioActivity Types:
Kd(11)
 
 
IC50(6)
 
 
Substance Types:
Chemical(33)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 33   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103452885]
[CID44395506]
IC50 0.0104Inhibitory concentration against TNF-alpha release in LPS treated whole blood [AID247750, Type: Literature]
View
2
[SID103272899]
[CID9886977]
IC50 0.048Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature]
View
3
[SID103273474]
[CID9907830]
IC50 0.269Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature]
View
4
[SID103272825]
[CID11783486]
IC50 0.928Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature]
View
5
[SID103185380]
[CID119031]
IC50 1.001Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature]
View
6
[SID103273528]
[CID11824148]
IC50 1.606Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature]
View
7
[SID103562257]
[CID5327044]
Kd 5.36Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 5 % DMSO as solvent [AID733376, Type: confirmatory]
View
8
[SID103562257]
[CID5327044]
Kd 5.36Binding affinity to GST-tagged human TNF-alpha in 10 mM citrate-phosphate at pH 6.5 by fluorescence assay [AID733384, Type: confirmatory]
View
9
[SID103562257]
[CID5327044]
Kd 5.7Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 2.5 % DMSO as solvent [AID733383, Type: confirmatory]
View
10
[SID103562257]
[CID5327044]
Kd 5.75Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 2.5 % PEG3350 as solvent [AID733381, Type: confirmatory]
View
11
[SID103562257]
[CID5327044]
Kd 6.18Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 5 % PEG3350 as solvent [AID733374, Type: confirmatory]
View
12
[SID103562257]
[CID5327044]
Kd 7.34Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 10 % DMSO as solvent [AID733382, Type: confirmatory]
View
13
[SID103562257]
[CID5327044]
Kd 7.51Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 2.5 % DMF as solvent [AID733380, Type: confirmatory]
View
14
[SID103562257]
[CID5327044]
Kd 8.3Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 2.5 % MeOH as solvent [AID733375, Type: confirmatory]
View
15
[SID103562257]
[CID5327044]
Kd 8.44Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 10 % PEG3350 as solvent [AID733379, Type: confirmatory]
View
16
[SID103562257]
[CID5327044]
Kd 9.77Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 5 % MeOH as solvent [AID732924, Type: confirmatory]
View
17
[SID103562257]
[CID5327044]
Kd 11.81Binding affinity to GST-tagged human TNF-alpha by fluorescence assay in presence of 10 % MeOH as solvent [AID732923, Type: confirmatory]
View
18
[SID103771203]
TNF-alpha inhibitor [AID742688, Type: Literature]
View
19
[SID103771314]
TNF-alpha inhibitor [AID742688, Type: other]
View
20
[SID103771449]
TNF-alpha inhibitor [AID742688, Type: other]
View