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Metabotropic glutamate receptor 5; mGluR5 [gi:1170947] - Target BioActivity Data
Filters: All Data » Active      
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BioActivity Outcomes:
Active(1107)
 
 
BioAssay Types:
Literature(1106)
 
 
Confirmatory(1)
 
 
BioActivity Types:
IC50(470)
 
 
EC50(342)
 
 
Ki(281)
 
 
Kd(5)
 
 
Substance Types:
Chemical(1107)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 99    Data Row: 1107   Total Pages: 56   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103520919]
[CID16737207]
IC50 3.6e-05Displacement of [3H]MPEP from mGluR5 in rat brain membrane [AID291620, Type: Literature]
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2
[SID103520919]
[CID16737207]
Ki 3.6e-05Displacement of [3H]MPEP from mGluR5 in rat brain [AID570310, Type: Literature]
View
3
[SID103520920]
[CID16737208]
IC50 6e-05Displacement of [3H]MPEP from mGluR5 in rat brain membrane [AID291620, Type: Literature]
View
4
[SID103614357]
[CID44574111]
Ki 8e-05Displacement of [3H]MPEP from mGluR5 in rat brain [AID570310, Type: Literature]
View
5
[SID131284870]
[CID53249063]
Ki 0.000106Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation counting [AID601416, Type: Literature]
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6
[SID131276868]
[CID53249062]
Ki 0.000127Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation counting [AID601416, Type: Literature]
View
7
[SID131280906]
[CID46208249]
Ki 0.0002Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation counting [AID601416, Type: Literature]
View
8
[SID103256385]
[CID3025961]
IC50 0.0002Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assay [AID299817, Type: Literature]
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9
[SID103520925]
[CID16736578]
IC50 0.00023Displacement of [3H]MPEP from mGluR5 in rat brain membrane [AID291620, Type: Literature]
View
10
[SID103478374]
[CID11535913]
Ki 0.00025Displacement of [3H]MPEP from mGluR5 in rat brain membranes [AID259885, Type: Literature]
View
11
[SID124968322]
[CID51050145]
Ki 0.00025Displacement of [3H]MPEP from mGluR5 in rat brain [AID570310, Type: Literature]
View
12
[SID124960417]
[CID51039242]
Ki 0.00027Displacement of [3H]MPEP from mGluR5 in rat brain [AID570310, Type: Literature]
View
13
[SID124968324]
[CID51050257]
Ki 0.00028Displacement of [3H]MPEP from mGluR5 in rat brain [AID570310, Type: Literature]
View
14
[SID131286927]
[CID53249064]
Ki 0.0003Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation counting [AID601416, Type: Literature]
View
15
[SID131278895]
[CID53249061]
IC50 0.00032Antagonist activity at rat mGluR5 expressed in human HEK-293 cells assessed as inhibition of glutamate-induced intracellular calcium mobilization [AID601415, Type: Literature]
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16
[SID131280842]
[CID54584297]
Ki 0.00036Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation counting [AID601416, Type: Literature]
View
17
[SID103614357]
[CID44574111]
Ki 0.00036Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation counting [AID601416, Type: Literature]
View
18
[SID131278896]
[CID54583366]
IC50 0.00039Antagonist activity at rat mGluR5 expressed in human HEK-293 cells assessed as inhibition of glutamate-induced intracellular calcium mobilization [AID601415, Type: Literature]
View
19
[SID124971325]
[CID51039243]
Ki 0.0004Displacement of [3H]MPEP from mGluR5 in rat brain [AID570310, Type: Literature]
View
20
[SID103447884]
[CID11378977]
IC50 0.000415Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as glutamate-induced calcium flux preincubated for 140 sec before glutamate challenge by calcium fluorescence assay [AID375051, Type: Literature]
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