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BioActivity Data for Gene Gsk3b (Gene ID:56637)

Also known as: 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3.
Filters: All Data » Active      
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BioActivity Outcomes:
Active(24)
 
 
BioAssay Types:
Literature(23)
 
 
Confirmatory(1)
 
 
BioAssay Categories:
Biochemical(24)
 
 
Cell-based(18)
 
 
BioActivity Types:
EC50(3)
 
 
IC50(3)
 
 
Kd(1)
 
 
Ki(1)
 
 
Substance Types:
Chemical(24)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 24   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124959646]
[CID25167072]
Ki 0.01Inhibition of recombinant mouse GSK3beta expressed in COS-1 cells by luciferase reporter gene assay [AID1120321, Type: confirmatory] [gi:11133187]
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2
[SID103567441]
[CID9549289]
IC50 0.03Binding affinity to GSK-3 beta in mouse D3 cells [AID512622, Type: Literature] [gi:11133187]
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3
[SID163317814]
[CID10118131]
IC50 0.047Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysis [AID706592, Type: Literature] [gi:11133187]
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4
[SID163328085]
[CID10138033]
IC50 0.087Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysis [AID706592, Type: Literature] [gi:11133187]
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5
[SID103567441]
[CID9549289]
Kd 0.126Inhibition of GSK-3 beta in mouse D3 cells [AID512611, Type: Literature] [gi:11133187]
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6
[SID103567441]
[CID9549289]
EC50 1Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker beta3-tubulin by immunofluorescence method [AID512614, Type: Literature] [gi:11133187]
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7
[SID103567441]
[CID9549289]
EC50 1Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker neurofilament-M by immunofluorescence method [AID512613, Type: Literature] [gi:11133187]
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8
[SID103567441]
[CID9549289]
EC50 1Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker microtubule-associated protein 2 by immunofluorescence method [AID512612, Type: Literature] [gi:11133187]
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9
[SID163320635]
[CID51000510]
Inhibition of GSK3beta-mediated Tau S202/T205 phosphorylation in mouse N2A cells at 2.6 to 24 uM after 16 hrs by immunoblot analysis [AID697304, Type: Literature] [gi:11133187]
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10
[SID103720231]
[CID46227308]
Inhibition of GSK-3-beta-mediated tau phosphorylation in mouse granule cerebellar neurons cells after 16 hrs by Western blot [AID452298, Type: Literature] [gi:11133187]
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11
[SID103382886]
[CID5101506]
Inhibition of GSK-3-beta-mediated tau phosphorylation in mouse granule cerebellar neurons cells after 16 hrs by Western blot [AID452298, Type: Literature] [gi:11133187]
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12
[SID103382696]
[CID6539169]
Inhibition of GSK-3-beta-mediated tau phosphorylation in mouse granule cerebellar neurons cells after 16 hrs by Western blot [AID452298, Type: Literature] [gi:11133187]
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13
[SID103382695]
[CID6539167]
Inhibition of GSK-3-beta-mediated tau phosphorylation in mouse granule cerebellar neurons cells after 16 hrs by Western blot [AID452298, Type: Literature] [gi:11133187]
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14
[SID103382658]
[CID6539170]
Inhibition of GSK-3-beta-mediated tau phosphorylation in mouse granule cerebellar neurons cells after 16 hrs by Western blot [AID452298, Type: Literature] [gi:11133187]
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15
[SID103382353]
[CID2757188]
Inhibition of GSK-3-beta-mediated tau phosphorylation in mouse granule cerebellar neurons cells after 16 hrs by Western blot [AID452298, Type: Literature] [gi:11133187]
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16
[SID103632640]
[CID16741475]
Inhibition of GSK3beta in mouse MA-10 cells assessed as stimulation of progesterone production at 100 uM after 2 hrs by RIA [AID751046, Type: Literature] [gi:11133187]
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17
[SID174521987]
[CID71734936]
Inhibition of GSK3beta in mouse MA-10 cells assessed as stimulation of progesterone production at 100 uM after 2 hrs by RIA [AID751046, Type: Literature] [gi:11133187]
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18
[SID174516803]
[CID71734937]
Inhibition of GSK3beta in mouse MA-10 cells assessed as stimulation of progesterone production at 100 uM after 2 hrs by RIA [AID751046, Type: Literature] [gi:11133187]
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19
[SID174516802]
[CID71734935]
Inhibition of GSK3beta in mouse MA-10 cells assessed as stimulation of progesterone production at 100 uM after 2 hrs by RIA [AID751046, Type: Literature] [gi:11133187]
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20
[SID174506610]
[CID71734860]
Inhibition of GSK3beta in mouse MA-10 cells assessed as stimulation of progesterone production at 100 uM after 2 hrs by RIA [AID751046, Type: Literature] [gi:11133187]
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