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BioAssay: AID 504749

qHTS profiling for inhibitors of Plasmodium falciparum proliferation

Plasmodium falciparum is a virulent malarial parasite that kills 1-2 million people worldwide each year. Transmitted by mosquitoes, the sporozoite form of the parasite enters the blood stream to infect hepatocytes, where they become merozoites that infect red blood cells (erythrocytes). Within erythrocytes, merozoites begin a 72-hour cycle of growth and division, after which the parasite is more ..
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 Tested Compounds
 Tested Compounds
All(2813)
 
 
Unspecified(2813)
 
 
 Tested Substances
 Tested Substances
All(3169)
 
 
Unspecified(3169)
 
 
 Related BioAssays
 Related BioAssays
AID: 504749
Data Source: NCGC (SYBR728)
BioAssay Type: Panel
Depositor Category: Other
BioAssay Version:
Deposit Date: 2011-05-11
Hold-until Date: 2011-08-15
Modify Date: 2011-08-16

Data Table ( Complete ):           View All Data
Tested Compounds:
Description:
NIH National Institute of Allergy and Infectious Diseases [NIAID]
NIH Chemical Genomics Center [NCGC]

MLPCN Grant: None
Assay Provider: Xinzhuan Su, NIAID

NCGC Assay Overview:

Plasmodium falciparum is a virulent malarial parasite that kills 1-2 million people worldwide each year. Transmitted by mosquitoes, the sporozoite form of the parasite enters the blood stream to infect hepatocytes, where they become merozoites that infect red blood cells (erythrocytes). Within erythrocytes, merozoites begin a 72-hour cycle of growth and division, after which the parasite is released to infect new red blood cells. Gametocytes, which form within erythrocytes as well, circulate in the bloodstream and are ingested by the mosquito, thereby completing the life cycle. To profile malarial isolates for differential chemical responses and to identify inhibitors of malarial growth, an assay that measures P. falciparum growth and replication within erythrocytes was employed. This assay uses a DNA binding fluorescent dye (SYBR Green) to detect parasite DNA following cell lysis. Because mature erythrocytes lack DNA, only Plasmodium-derived DNA is detected.
Panel Information
Assay Panel for qHTS profiling for inhibitors of Plasmodium falciparum proliferation - A set of small molecules profiled against a panel of 61 malarial parasites
    Data Table(All)Show more
PID§NameSubstancePanel TargetsDescription
ActiveInactive
1DFO20362652210
2CP2032412105
3W26611565
4AS1203612094
5CP2912312114
6ATS1892722155
7TAB1132932129
8CP1913142099
9CP1921782316
10PC492062329
11CP2472842087
12CP1942172122
13P94_403452029
14CP2011622318
15TAB1093332035
16CP1852422222
17CP2863422118
183D73022184
197G86831649
20DIV302712098
21HB32902223
22CP3052182204
23GB44141864
24CP2374162002
25CP2382522241
26Dd24632024
27CP3353111925
28CP2682042178
29CP2652822139
30CP2661312161
31CP2621602334
32ECU3282146
33PC262652022
34ATS952802100
35PAD2932132
36CP2692512179
374563052197
38CP3251962244
39P93_243571962
40C2A2562268
41CP3291822290
42SC27B2822203
43CP2562802159
44CP2502472213
45CP2152352028
462242962148
47CP2522542223
48CP2172832173
49FAB91722435
50CP2112152213
51PC152532204
52N1403582096
53DIV174381864
54AA10293322113
55DIV144431835
56TAB1653992009
57ICS5641794
58CP2603461957
59CP3151622334
60CP2972622042
61JCK1692362

§ Panel component ID.
Protocol
NCGC Assay Protocol Summary:

The SYBR Green viability assay was adapted from a method described previously (Plouffe et al., 2008). For screening 3 ul culture medium was dispensed into 1536 well black clear bottom plates (Aurora Biotechnologies) using a Multidrop Combi (Thermo Fisher Scientific Inc.), 23 nL compounds in DMSO were added by a pin tool (Kalypsys), and 5 ul of erythrocytes infected with P. falciparum (0.3% parasitemia, 2.5% hematocrit final concentration) were added. The plates were incubated at 37 C in a humidified incubator in 5% CO2 for 72 h, and 2 ul lysis buffer (20 mM Tris HCl, 10 mM EDTA, 0.16% saponin, 1.6% triton X, 10X SYBR Green I supplied as 10,000X final concentration by Invitrogen) was added to each well. The plates were mixed for 25 sec with gentle shaking and incubated overnight at room temperature in the dark. The following morning, fluorescence intensity at 485(14) nm excitation and 535(25) nm emission wavelengths was measured on an EnVision (Perkin Elmer) plate reader. Plate reads were normalized relative to the control inhibitor (0.29 uM artemisinin) and vehicle (DMSO) wells present on each plate and then corrected by an algorithm using vehicle-only control plates at the beginning and end of the compound plate stack.
Comment
This is a profiling assay where compounds were screened against a panel of 61 malarial parasites. Ranking of compounds within each parasite is described below.

Compound Ranking:

1. Compounds are first classified as having full titration curves, partial modulation, partial curve (weaker actives), single point activity (at highest concentration only), or inactive. See data field "Curve Description". For this assay, apparent inhibitors are ranked higher than compounds that showed apparent activation.
2. For all inactive compounds, PUBCHEM_ACTIVITY_SCORE is 0. For all active compounds, a score range was given for each curve class type given above. Active compounds have PUBCHEM_ACTIVITY_SCORE between 40 and 100. Inconclusive compounds have PUBCHEM_ACTIVITY_SCORE between 1 and 39. Fit_LogAC50 was used for determining relative score and was scaled to each curve class' score range.
Result Definitions
Show more
TIDNameDescriptionPID§Panel TargetsHistogramTypeUnit
OutcomeThe BioAssay activity outcomeOutcome
1DFO2036-Outcome1Outcome
2DFO2036-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.1String
3DFO2036-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.1FloatμM
4DFO2036-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.1Float%
5DFO2036-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.1String
6DFO2036-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.1String
7DFO2036-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).1Float
8DFO2036-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.1Float
9DFO2036-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.1Float
10DFO2036-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.1Float%
11DFO2036-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.1Float%
12DFO2036-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.1Float
13DFO2036-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.1String
14DFO2036-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).1Float%
15DFO2036-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.1Float%
16DFO2036-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.1Float%
17DFO2036-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.1Float%
18DFO2036-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.1Float%
19DFO2036-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.1Float%
20DFO2036-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.1Float%
21DFO2036-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.1Float%
22DFO2036-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.1Float%
23DFO2036-Activity at 0.047 uM (0.0472851μM**)% Activity at given concentration.1Float%
24DFO2036-Activity at 0.103 uM (0.102874μM**)% Activity at given concentration.1Float%
25DFO2036-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.1Float%
26DFO2036-Activity at 0.529 uM (0.528832μM**)% Activity at given concentration.1Float%
27DFO2036-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.1Float%
28DFO2036-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.1Float%
29DFO2036-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.1Float%
30DFO2036-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.1Float%
31DFO2036-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.1Float%
32CP203-Outcome2Outcome
33CP203-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.2String
34CP203-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.2FloatμM
35CP203-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.2Float%
36CP203-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.2String
37CP203-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.2String
38CP203-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).2Float
39CP203-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.2Float
40CP203-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.2Float
41CP203-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.2Float%
42CP203-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.2Float%
43CP203-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.2Float
44CP203-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.2String
45CP203-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).2Float%
46CP203-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.2Float%
47CP203-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.2Float%
48CP203-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.2Float%
49CP203-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.2Float%
50CP203-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.2Float%
51CP203-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.2Float%
52CP203-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.2Float%
53CP203-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.2Float%
54CP203-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.2Float%
55CP203-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.2Float%
56CP203-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.2Float%
57CP203-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.2Float%
58CP203-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.2Float%
59CP203-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.2Float%
60CP203-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.2Float%
61CP203-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.2Float%
62CP203-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.2Float%
63W2-Outcome3Outcome
64W2-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.3String
65W2-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.3FloatμM
66W2-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.3Float%
67W2-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.3String
68W2-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.3String
69W2-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).3Float
70W2-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.3Float
71W2-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.3Float
72W2-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.3Float%
73W2-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.3Float%
74W2-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.3Float
75W2-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.3String
76W2-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).3Float%
77W2-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.3Float%
78W2-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.3Float%
79W2-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.3Float%
80W2-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.3Float%
81W2-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.3Float%
82W2-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.3Float%
83W2-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.3Float%
84W2-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.3Float%
85W2-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.3Float%
86W2-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.3Float%
87W2-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.3Float%
88W2-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.3Float%
89W2-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.3Float%
90W2-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.3Float%
91W2-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.3Float%
92W2-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.3Float%
93W2-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.3Float%
94AS120-Outcome4Outcome
95AS120-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.4String
96AS120-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.4FloatμM
97AS120-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.4Float%
98AS120-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.4String
99AS120-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.4String
100AS120-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).4Float
101AS120-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.4Float
102AS120-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.4Float
103AS120-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.4Float%
104AS120-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.4Float%
105AS120-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.4Float
106AS120-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.4String
107AS120-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).4Float%
108AS120-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.4Float%
109AS120-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.4Float%
110AS120-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.4Float%
111AS120-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.4Float%
112AS120-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.4Float%
113AS120-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.4Float%
114AS120-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.4Float%
115AS120-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.4Float%
116AS120-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.4Float%
117AS120-Activity at 0.107 uM (0.106749μM**)% Activity at given concentration.4Float%
118AS120-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.4Float%
119AS120-Activity at 0.534 uM (0.533744μM**)% Activity at given concentration.4Float%
120AS120-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.4Float%
121AS120-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.4Float%
122AS120-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.4Float%
123AS120-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.4Float%
124AS120-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.4Float%
125CP291-Outcome5Outcome
126CP291-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.5String
127CP291-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.5FloatμM
128CP291-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.5Float%
129CP291-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.5String
130CP291-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.5String
131CP291-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).5Float
132CP291-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.5Float
133CP291-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.5Float
134CP291-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.5Float%
135CP291-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.5Float%
136CP291-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.5Float
137CP291-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.5String
138CP291-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).5Float%
139CP291-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.5Float%
140CP291-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.5Float%
141CP291-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.5Float%
142CP291-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.5Float%
143CP291-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.5Float%
144CP291-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.5Float%
145CP291-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.5Float%
146CP291-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.5Float%
147CP291-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.5Float%
148CP291-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.5Float%
149CP291-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.5Float%
150CP291-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.5Float%
151CP291-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.5Float%
152CP291-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.5Float%
153CP291-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.5Float%
154CP291-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.5Float%
155CP291-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.5Float%
156ATS189-Outcome6Outcome
157ATS189-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.6String
158ATS189-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.6FloatμM
159ATS189-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.6Float%
160ATS189-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.6String
161ATS189-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.6String
162ATS189-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).6Float
163ATS189-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.6Float
164ATS189-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.6Float
165ATS189-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.6Float%
166ATS189-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.6Float%
167ATS189-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.6Float
168ATS189-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.6String
169ATS189-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).6Float%
170ATS189-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.6Float%
171ATS189-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.6Float%
172ATS189-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.6Float%
173ATS189-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.6Float%
174ATS189-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.6Float%
175ATS189-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.6Float%
176ATS189-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.6Float%
177ATS189-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.6Float%
178ATS189-Activity at 0.047 uM (0.0472785μM**)% Activity at given concentration.6Float%
179ATS189-Activity at 0.103 uM (0.102759μM**)% Activity at given concentration.6Float%
180ATS189-Activity at 0.230 uM (0.229856μM**)% Activity at given concentration.6Float%
181ATS189-Activity at 0.529 uM (0.528537μM**)% Activity at given concentration.6Float%
182ATS189-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.6Float%
183ATS189-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.6Float%
184ATS189-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.6Float%
185ATS189-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.6Float%
186ATS189-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.6Float%
187TAB113-Outcome7Outcome
188TAB113-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.7String
189TAB113-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.7FloatμM
190TAB113-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.7Float%
191TAB113-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.7String
192TAB113-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.7String
193TAB113-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).7Float
194TAB113-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.7Float
195TAB113-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.7Float
196TAB113-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.7Float%
197TAB113-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.7Float%
198TAB113-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.7Float
199TAB113-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.7String
200TAB113-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).7Float%
201TAB113-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.7Float%
202TAB113-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.7Float%
203TAB113-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.7Float%
204TAB113-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.7Float%
205TAB113-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.7Float%
206TAB113-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.7Float%
207TAB113-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.7Float%
208TAB113-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.7Float%
209TAB113-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.7Float%
210TAB113-Activity at 0.107 uM (0.106749μM**)% Activity at given concentration.7Float%
211TAB113-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.7Float%
212TAB113-Activity at 0.534 uM (0.533744μM**)% Activity at given concentration.7Float%
213TAB113-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.7Float%
214TAB113-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.7Float%
215TAB113-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.7Float%
216TAB113-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.7Float%
217TAB113-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.7Float%
218CP191-Outcome8Outcome
219CP191-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.8String
220CP191-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.8FloatμM
221CP191-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.8Float%
222CP191-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.8String
223CP191-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.8String
224CP191-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).8Float
225CP191-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.8Float
226CP191-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.8Float
227CP191-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.8Float%
228CP191-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.8Float%
229CP191-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.8Float
230CP191-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.8String
231CP191-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).8Float%
232CP191-Activity at 0.0000822400 uM (8.224e-05μM**)% Activity at given concentration.8Float%
233CP191-Activity at 0.0003676000 uM (0.0003676μM**)% Activity at given concentration.8Float%
234CP191-Activity at 0.0008456430 uM (0.000845643μM**)% Activity at given concentration.8Float%
235CP191-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.8Float%
236CP191-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.8Float%
237CP191-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.8Float%
238CP191-Activity at 0.021 uM (0.02055μM**)% Activity at given concentration.8Float%
239CP191-Activity at 0.023 uM (0.02299μM**)% Activity at given concentration.8Float%
240CP191-Activity at 0.047 uM (0.0472789μM**)% Activity at given concentration.8Float%
241CP191-Activity at 0.103 uM (0.1028μM**)% Activity at given concentration.8Float%
242CP191-Activity at 0.230 uM (0.229875μM**)% Activity at given concentration.8Float%
243CP191-Activity at 0.528 uM (0.528494μM**)% Activity at given concentration.8Float%
244CP191-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.8Float%
245CP191-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.8Float%
246CP191-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.8Float%
247CP191-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.8Float%
248CP191-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.8Float%
249CP192-Outcome9Outcome
250CP192-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.9String
251CP192-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.9FloatμM
252CP192-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.9Float%
253CP192-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.9String
254CP192-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.9String
255CP192-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).9Float
256CP192-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.9Float
257CP192-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.9Float
258CP192-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.9Float%
259CP192-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.9Float%
260CP192-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.9Float
261CP192-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.9String
262CP192-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).9Float%
263CP192-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.9Float%
264CP192-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.9Float%
265CP192-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.9Float%
266CP192-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.9Float%
267CP192-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.9Float%
268CP192-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.9Float%
269CP192-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.9Float%
270CP192-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.9Float%
271CP192-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.9Float%
272CP192-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.9Float%
273CP192-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.9Float%
274CP192-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.9Float%
275CP192-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.9Float%
276CP192-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.9Float%
277CP192-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.9Float%
278CP192-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.9Float%
279CP192-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.9Float%
280PC49-Outcome10Outcome
281PC49-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.10String
282PC49-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.10FloatμM
283PC49-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.10Float%
284PC49-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.10String
285PC49-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.10String
286PC49-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).10Float
287PC49-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.10Float
288PC49-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.10Float
289PC49-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.10Float%
290PC49-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.10Float%
291PC49-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.10Float
292PC49-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.10String
293PC49-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).10Float%
294PC49-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.10Float%
295PC49-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.10Float%
296PC49-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.10Float%
297PC49-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.10Float%
298PC49-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.10Float%
299PC49-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.10Float%
300PC49-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.10Float%
301PC49-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.10Float%
302PC49-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.10Float%
303PC49-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.10Float%
304PC49-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.10Float%
305PC49-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.10Float%
306PC49-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.10Float%
307PC49-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.10Float%
308PC49-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.10Float%
309PC49-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.10Float%
310PC49-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.10Float%
311CP247-Outcome11Outcome
312CP247-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.11String
313CP247-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.11FloatμM
314CP247-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.11Float%
315CP247-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.11String
316CP247-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.11String
317CP247-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).11Float
318CP247-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.11Float
319CP247-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.11Float
320CP247-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.11Float%
321CP247-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.11Float%
322CP247-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.11Float
323CP247-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.11String
324CP247-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).11Float%
325CP247-Activity at 0.0000822414 uM (8.22414e-05μM**)% Activity at given concentration.11Float%
326CP247-Activity at 0.0001738940 uM (0.000173894μM**)% Activity at given concentration.11Float%
327CP247-Activity at 0.0003676724 uM (0.000367672μM**)% Activity at given concentration.11Float%
328CP247-Activity at 0.0008408640 uM (0.000840864μM**)% Activity at given concentration.11Float%
329CP247-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.11Float%
330CP247-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.11Float%
331CP247-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.11Float%
332CP247-Activity at 0.021 uM (0.0205517μM**)% Activity at given concentration.11Float%
333CP247-Activity at 0.023 uM (0.0229885μM**)% Activity at given concentration.11Float%
334CP247-Activity at 0.047 uM (0.0472785μM**)% Activity at given concentration.11Float%
335CP247-Activity at 0.103 uM (0.102759μM**)% Activity at given concentration.11Float%
336CP247-Activity at 0.230 uM (0.229856μM**)% Activity at given concentration.11Float%
337CP247-Activity at 0.529 uM (0.528537μM**)% Activity at given concentration.11Float%
338CP247-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.11Float%
339CP247-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.11Float%
340CP247-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.11Float%
341CP247-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.11Float%
342CP247-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.11Float%
343CP194-Outcome12Outcome
344CP194-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.12String
345CP194-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.12FloatμM
346CP194-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.12Float%
347CP194-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.12String
348CP194-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.12String
349CP194-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).12Float
350CP194-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.12Float
351CP194-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.12Float
352CP194-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.12Float%
353CP194-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.12Float%
354CP194-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.12Float
355CP194-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.12String
356CP194-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).12Float%
357CP194-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.12Float%
358CP194-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.12Float%
359CP194-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.12Float%
360CP194-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.12Float%
361CP194-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.12Float%
362CP194-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.12Float%
363CP194-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.12Float%
364CP194-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.12Float%
365CP194-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.12Float%
366CP194-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.12Float%
367CP194-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.12Float%
368CP194-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.12Float%
369CP194-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.12Float%
370CP194-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.12Float%
371CP194-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.12Float%
372CP194-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.12Float%
373CP194-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.12Float%
374P94_40-Outcome13Outcome
375P94_40-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.13String
376P94_40-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.13FloatμM
377P94_40-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.13Float%
378P94_40-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.13String
379P94_40-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.13String
380P94_40-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).13Float
381P94_40-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.13Float
382P94_40-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.13Float
383P94_40-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.13Float%
384P94_40-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.13Float%
385P94_40-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.13Float
386P94_40-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.13String
387P94_40-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).13Float%
388P94_40-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.13Float%
389P94_40-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.13Float%
390P94_40-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.13Float%
391P94_40-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.13Float%
392P94_40-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.13Float%
393P94_40-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.13Float%
394P94_40-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.13Float%
395P94_40-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.13Float%
396P94_40-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.13Float%
397P94_40-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.13Float%
398P94_40-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.13Float%
399P94_40-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.13Float%
400P94_40-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.13Float%
401P94_40-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.13Float%
402P94_40-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.13Float%
403P94_40-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.13Float%
404P94_40-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.13Float%
405CP201-Outcome14Outcome
406CP201-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.14String
407CP201-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.14FloatμM
408CP201-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.14Float%
409CP201-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.14String
410CP201-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.14String
411CP201-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).14Float
412CP201-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.14Float
413CP201-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.14Float
414CP201-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.14Float%
415CP201-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.14Float%
416CP201-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.14Float
417CP201-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.14String
418CP201-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).14Float%
419CP201-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.14Float%
420CP201-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.14Float%
421CP201-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.14Float%
422CP201-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.14Float%
423CP201-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.14Float%
424CP201-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.14Float%
425CP201-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.14Float%
426CP201-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.14Float%
427CP201-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.14Float%
428CP201-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.14Float%
429CP201-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.14Float%
430CP201-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.14Float%
431CP201-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.14Float%
432CP201-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.14Float%
433CP201-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.14Float%
434CP201-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.14Float%
435CP201-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.14Float%
436TAB109-Outcome15Outcome
437TAB109-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.15String
438TAB109-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.15FloatμM
439TAB109-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.15Float%
440TAB109-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.15String
441TAB109-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.15String
442TAB109-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).15Float
443TAB109-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.15Float
444TAB109-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.15Float
445TAB109-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.15Float%
446TAB109-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.15Float%
447TAB109-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.15Float
448TAB109-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.15String
449TAB109-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).15Float%
450TAB109-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.15Float%
451TAB109-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.15Float%
452TAB109-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.15Float%
453TAB109-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.15Float%
454TAB109-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.15Float%
455TAB109-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.15Float%
456TAB109-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.15Float%
457TAB109-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.15Float%
458TAB109-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.15Float%
459TAB109-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.15Float%
460TAB109-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.15Float%
461TAB109-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.15Float%
462TAB109-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.15Float%
463TAB109-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.15Float%
464TAB109-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.15Float%
465TAB109-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.15Float%
466TAB109-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.15Float%
467CP185-Outcome16Outcome
468CP185-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.16String
469CP185-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.16FloatμM
470CP185-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.16Float%
471CP185-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.16String
472CP185-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.16String
473CP185-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).16Float
474CP185-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.16Float
475CP185-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.16Float
476CP185-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.16Float%
477CP185-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.16Float%
478CP185-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.16Float
479CP185-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.16String
480CP185-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).16Float%
481CP185-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.16Float%
482CP185-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.16Float%
483CP185-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.16Float%
484CP185-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.16Float%
485CP185-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.16Float%
486CP185-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.16Float%
487CP185-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.16Float%
488CP185-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.16Float%
489CP185-Activity at 0.047 uM (0.0472785μM**)% Activity at given concentration.16Float%
490CP185-Activity at 0.103 uM (0.102759μM**)% Activity at given concentration.16Float%
491CP185-Activity at 0.230 uM (0.229856μM**)% Activity at given concentration.16Float%
492CP185-Activity at 0.529 uM (0.528537μM**)% Activity at given concentration.16Float%
493CP185-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.16Float%
494CP185-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.16Float%
495CP185-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.16Float%
496CP185-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.16Float%
497CP185-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.16Float%
498CP286-Outcome17Outcome
499CP286-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.17String
500CP286-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.17FloatμM
501CP286-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.17Float%
502CP286-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.17String
503CP286-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.17String
504CP286-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).17Float
505CP286-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.17Float
506CP286-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.17Float
507CP286-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.17Float%
508CP286-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.17Float%
509CP286-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.17Float
510CP286-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.17String
511CP286-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).17Float%
512CP286-Activity at 0.0000367800 uM (3.678e-05μM**)% Activity at given concentration.17Float%
513CP286-Activity at 0.0001706587 uM (0.000170659μM**)% Activity at given concentration.17Float%
514CP286-Activity at 0.0003678000 uM (0.0003678μM**)% Activity at given concentration.17Float%
515CP286-Activity at 0.0008533627 uM (0.000853363μM**)% Activity at given concentration.17Float%
516CP286-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.17Float%
517CP286-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.17Float%
518CP286-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.17Float%
519CP286-Activity at 0.021 uM (0.0213331μM**)% Activity at given concentration.17Float%
520CP286-Activity at 0.046 uM (0.04598μM**)% Activity at given concentration.17Float%
521CP286-Activity at 0.107 uM (0.106685μM**)% Activity at given concentration.17Float%
522CP286-Activity at 0.230 uM (0.2299μM**)% Activity at given concentration.17Float%
523CP286-Activity at 0.533 uM (0.533347μM**)% Activity at given concentration.17Float%
524CP286-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.17Float%
525CP286-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.17Float%
526CP286-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.17Float%
527CP286-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.17Float%
528CP286-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.17Float%
5293D7-Outcome18Outcome
5303D7-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.18String
5313D7-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.18FloatμM
5323D7-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.18Float%
5333D7-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.18String
5343D7-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.18String
5353D7-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).18Float
5363D7-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.18Float
5373D7-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.18Float
5383D7-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.18Float%
5393D7-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.18Float%
5403D7-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.18Float
5413D7-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.18String
5423D7-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).18Float%
5433D7-Activity at 0.0000367800 uM (3.678e-05μM**)% Activity at given concentration.18Float%
5443D7-Activity at 0.0001706587 uM (0.000170659μM**)% Activity at given concentration.18Float%
5453D7-Activity at 0.0003678000 uM (0.0003678μM**)% Activity at given concentration.18Float%
5463D7-Activity at 0.0008533627 uM (0.000853363μM**)% Activity at given concentration.18Float%
5473D7-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.18Float%
5483D7-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.18Float%
5493D7-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.18Float%
5503D7-Activity at 0.021 uM (0.0213331μM**)% Activity at given concentration.18Float%
5513D7-Activity at 0.046 uM (0.04598μM**)% Activity at given concentration.18Float%
5523D7-Activity at 0.107 uM (0.106685μM**)% Activity at given concentration.18Float%
5533D7-Activity at 0.230 uM (0.2299μM**)% Activity at given concentration.18Float%
5543D7-Activity at 0.533 uM (0.533347μM**)% Activity at given concentration.18Float%
5553D7-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.18Float%
5563D7-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.18Float%
5573D7-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.18Float%
5583D7-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.18Float%
5593D7-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.18Float%
5607G8-Outcome19Outcome
5617G8-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.19String
5627G8-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.19FloatμM
5637G8-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.19Float%
5647G8-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.19String
5657G8-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.19String
5667G8-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).19Float
5677G8-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.19Float
5687G8-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.19Float
5697G8-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.19Float%
5707G8-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.19Float%
5717G8-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.19Float
5727G8-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.19String
5737G8-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).19Float%
5747G8-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.19Float%
5757G8-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.19Float%
5767G8-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.19Float%
5777G8-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.19Float%
5787G8-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.19Float%
5797G8-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.19Float%
5807G8-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.19Float%
5817G8-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.19Float%
5827G8-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.19Float%
5837G8-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.19Float%
5847G8-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.19Float%
5857G8-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.19Float%
5867G8-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.19Float%
5877G8-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.19Float%
5887G8-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.19Float%
5897G8-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.19Float%
5907G8-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.19Float%
591DIV30-Outcome20Outcome
592DIV30-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.20String
593DIV30-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.20FloatμM
594DIV30-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.20Float%
595DIV30-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.20String
596DIV30-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.20String
597DIV30-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).20Float
598DIV30-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.20Float
599DIV30-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.20Float
600DIV30-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.20Float%
601DIV30-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.20Float%
602DIV30-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.20Float
603DIV30-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.20String
604DIV30-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).20Float%
605DIV30-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.20Float%
606DIV30-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.20Float%
607DIV30-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.20Float%
608DIV30-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.20Float%
609DIV30-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.20Float%
610DIV30-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.20Float%
611DIV30-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.20Float%
612DIV30-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.20Float%
613DIV30-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.20Float%
614DIV30-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.20Float%
615DIV30-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.20Float%
616DIV30-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.20Float%
617DIV30-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.20Float%
618DIV30-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.20Float%
619DIV30-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.20Float%
620DIV30-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.20Float%
621DIV30-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.20Float%
622HB3-Outcome21Outcome
623HB3-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.21String
624HB3-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.21FloatμM
625HB3-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.21Float%
626HB3-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.21String
627HB3-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.21String
628HB3-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).21Float
629HB3-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.21Float
630HB3-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.21Float
631HB3-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.21Float%
632HB3-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.21Float%
633HB3-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.21Float
634HB3-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.21String
635HB3-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).21Float%
636HB3-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.21Float%
637HB3-Activity at 0.0001738940 uM (0.000173894μM**)% Activity at given concentration.21Float%
638HB3-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.21Float%
639HB3-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.21Float%
640HB3-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.21Float%
641HB3-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.21Float%
642HB3-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.21Float%
643HB3-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.21Float%
644HB3-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.21Float%
645HB3-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.21Float%
646HB3-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.21Float%
647HB3-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.21Float%
648HB3-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.21Float%
649HB3-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.21Float%
650HB3-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.21Float%
651HB3-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.21Float%
652HB3-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.21Float%
653CP305-Outcome22Outcome
654CP305-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.22String
655CP305-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.22FloatμM
656CP305-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.22Float%
657CP305-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.22String
658CP305-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.22String
659CP305-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).22Float
660CP305-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.22Float
661CP305-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.22Float
662CP305-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.22Float%
663CP305-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.22Float%
664CP305-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.22Float
665CP305-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.22String
666CP305-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).22Float%
667CP305-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.22Float%
668CP305-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.22Float%
669CP305-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.22Float%
670CP305-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.22Float%
671CP305-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.22Float%
672CP305-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.22Float%
673CP305-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.22Float%
674CP305-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.22Float%
675CP305-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.22Float%
676CP305-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.22Float%
677CP305-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.22Float%
678CP305-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.22Float%
679CP305-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.22Float%
680CP305-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.22Float%
681CP305-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.22Float%
682CP305-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.22Float%
683CP305-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.22Float%
684GB4-Outcome23Outcome
685GB4-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.23String
686GB4-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.23FloatμM
687GB4-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.23Float%
688GB4-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.23String
689GB4-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.23String
690GB4-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).23Float
691GB4-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.23Float
692GB4-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.23Float
693GB4-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.23Float%
694GB4-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.23Float%
695GB4-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.23Float
696GB4-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.23String
697GB4-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).23Float%
698GB4-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.23Float%
699GB4-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.23Float%
700GB4-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.23Float%
701GB4-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.23Float%
702GB4-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.23Float%
703GB4-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.23Float%
704GB4-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.23Float%
705GB4-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.23Float%
706GB4-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.23Float%
707GB4-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.23Float%
708GB4-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.23Float%
709GB4-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.23Float%
710GB4-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.23Float%
711GB4-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.23Float%
712GB4-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.23Float%
713GB4-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.23Float%
714GB4-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.23Float%
715CP237-Outcome24Outcome
716CP237-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.24String
717CP237-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.24FloatμM
718CP237-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.24Float%
719CP237-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.24String
720CP237-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.24String
721CP237-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).24Float
722CP237-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.24Float
723CP237-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.24Float
724CP237-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.24Float%
725CP237-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.24Float%
726CP237-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.24Float
727CP237-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.24String
728CP237-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).24Float%
729CP237-Activity at 0.0000367800 uM (3.678e-05μM**)% Activity at given concentration.24Float%
730CP237-Activity at 0.0001706587 uM (0.000170659μM**)% Activity at given concentration.24Float%
731CP237-Activity at 0.0003678000 uM (0.0003678μM**)% Activity at given concentration.24Float%
732CP237-Activity at 0.0008533627 uM (0.000853363μM**)% Activity at given concentration.24Float%
733CP237-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.24Float%
734CP237-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.24Float%
735CP237-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.24Float%
736CP237-Activity at 0.021 uM (0.0213331μM**)% Activity at given concentration.24Float%
737CP237-Activity at 0.046 uM (0.04598μM**)% Activity at given concentration.24Float%
738CP237-Activity at 0.107 uM (0.106685μM**)% Activity at given concentration.24Float%
739CP237-Activity at 0.230 uM (0.2299μM**)% Activity at given concentration.24Float%
740CP237-Activity at 0.533 uM (0.533347μM**)% Activity at given concentration.24Float%
741CP237-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.24Float%
742CP237-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.24Float%
743CP237-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.24Float%
744CP237-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.24Float%
745CP237-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.24Float%
746CP238-Outcome25Outcome
747CP238-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.25String
748CP238-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.25FloatμM
749CP238-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.25Float%
750CP238-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.25String
751CP238-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.25String
752CP238-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).25Float
753CP238-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.25Float
754CP238-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.25Float
755CP238-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.25Float%
756CP238-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.25Float%
757CP238-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.25Float
758CP238-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.25String
759CP238-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).25Float%
760CP238-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.25Float%
761CP238-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.25Float%
762CP238-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.25Float%
763CP238-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.25Float%
764CP238-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.25Float%
765CP238-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.25Float%
766CP238-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.25Float%
767CP238-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.25Float%
768CP238-Activity at 0.047 uM (0.0472785μM**)% Activity at given concentration.25Float%
769CP238-Activity at 0.103 uM (0.102759μM**)% Activity at given concentration.25Float%
770CP238-Activity at 0.230 uM (0.229856μM**)% Activity at given concentration.25Float%
771CP238-Activity at 0.529 uM (0.528537μM**)% Activity at given concentration.25Float%
772CP238-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.25Float%
773CP238-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.25Float%
774CP238-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.25Float%
775CP238-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.25Float%
776CP238-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.25Float%
777Dd2-Outcome26Outcome
778Dd2-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.26String
779Dd2-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.26FloatμM
780Dd2-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.26Float%
781Dd2-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.26String
782Dd2-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.26String
783Dd2-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).26Float
784Dd2-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.26Float
785Dd2-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.26Float
786Dd2-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.26Float%
787Dd2-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.26Float%
788Dd2-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.26Float
789Dd2-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.26String
790Dd2-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).26Float%
791Dd2-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.26Float%
792Dd2-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.26Float%
793Dd2-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.26Float%
794Dd2-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.26Float%
795Dd2-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.26Float%
796Dd2-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.26Float%
797Dd2-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.26Float%
798Dd2-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.26Float%
799Dd2-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.26Float%
800Dd2-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.26Float%
801Dd2-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.26Float%
802Dd2-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.26Float%
803Dd2-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.26Float%
804Dd2-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.26Float%
805Dd2-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.26Float%
806Dd2-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.26Float%
807Dd2-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.26Float%
808CP335-Outcome27Outcome
809CP335-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.27String
810CP335-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.27FloatμM
811CP335-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.27Float%
812CP335-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.27String
813CP335-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.27String
814CP335-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).27Float
815CP335-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.27Float
816CP335-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.27Float
817CP335-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.27Float%
818CP335-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.27Float%
819CP335-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.27Float
820CP335-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.27String
821CP335-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).27Float%
822CP335-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.27Float%
823CP335-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.27Float%
824CP335-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.27Float%
825CP335-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.27Float%
826CP335-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.27Float%
827CP335-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.27Float%
828CP335-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.27Float%
829CP335-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.27Float%
830CP335-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.27Float%
831CP335-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.27Float%
832CP335-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.27Float%
833CP335-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.27Float%
834CP335-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.27Float%
835CP335-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.27Float%
836CP335-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.27Float%
837CP335-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.27Float%
838CP335-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.27Float%
839CP268-Outcome28Outcome
840CP268-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.28String
841CP268-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.28FloatμM
842CP268-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.28Float%
843CP268-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.28String
844CP268-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.28String
845CP268-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).28Float
846CP268-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.28Float
847CP268-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.28Float
848CP268-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.28Float%
849CP268-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.28Float%
850CP268-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.28Float
851CP268-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.28String
852CP268-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).28Float%
853CP268-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.28Float%
854CP268-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.28Float%
855CP268-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.28Float%
856CP268-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.28Float%
857CP268-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.28Float%
858CP268-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.28Float%
859CP268-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.28Float%
860CP268-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.28Float%
861CP268-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.28Float%
862CP268-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.28Float%
863CP268-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.28Float%
864CP268-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.28Float%
865CP268-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.28Float%
866CP268-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.28Float%
867CP268-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.28Float%
868CP268-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.28Float%
869CP268-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.28Float%
870CP265-Outcome29Outcome
871CP265-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.29String
872CP265-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.29FloatμM
873CP265-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.29Float%
874CP265-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.29String
875CP265-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.29String
876CP265-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).29Float
877CP265-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.29Float
878CP265-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.29Float
879CP265-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.29Float%
880CP265-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.29Float%
881CP265-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.29Float
882CP265-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.29String
883CP265-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).29Float%
884CP265-Activity at 0.0000822400 uM (8.224e-05μM**)% Activity at given concentration.29Float%
885CP265-Activity at 0.0001738769 uM (0.000173877μM**)% Activity at given concentration.29Float%
886CP265-Activity at 0.0003677000 uM (0.0003677μM**)% Activity at given concentration.29Float%
887CP265-Activity at 0.0008408811 uM (0.000840881μM**)% Activity at given concentration.29Float%
888CP265-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.29Float%
889CP265-Activity at 0.00435 uM (0.00434716μM**)% Activity at given concentration.29Float%
890CP265-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.29Float%
891CP265-Activity at 0.021 uM (0.02055μM**)% Activity at given concentration.29Float%
892CP265-Activity at 0.023 uM (0.02299μM**)% Activity at given concentration.29Float%
893CP265-Activity at 0.047 uM (0.0472789μM**)% Activity at given concentration.29Float%
894CP265-Activity at 0.103 uM (0.1028μM**)% Activity at given concentration.29Float%
895CP265-Activity at 0.230 uM (0.229875μM**)% Activity at given concentration.29Float%
896CP265-Activity at 0.528 uM (0.528494μM**)% Activity at given concentration.29Float%
897CP265-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.29Float%
898CP265-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.29Float%
899CP265-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.29Float%
900CP265-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.29Float%
901CP265-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.29Float%
902CP266-Outcome30Outcome
903CP266-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.30String
904CP266-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.30FloatμM
905CP266-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.30Float%
906CP266-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.30String
907CP266-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.30String
908CP266-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).30Float
909CP266-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.30Float
910CP266-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.30Float
911CP266-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.30Float%
912CP266-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.30Float%
913CP266-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.30Float
914CP266-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.30String
915CP266-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).30Float%
916CP266-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.30Float%
917CP266-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.30Float%
918CP266-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.30Float%
919CP266-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.30Float%
920CP266-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.30Float%
921CP266-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.30Float%
922CP266-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.30Float%
923CP266-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.30Float%
924CP266-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.30Float%
925CP266-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.30Float%
926CP266-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.30Float%
927CP266-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.30Float%
928CP266-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.30Float%
929CP266-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.30Float%
930CP266-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.30Float%
931CP266-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.30Float%
932CP266-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.30Float%
933CP262-Outcome31Outcome
934CP262-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.31String
935CP262-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.31FloatμM
936CP262-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.31Float%
937CP262-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.31String
938CP262-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.31String
939CP262-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).31Float
940CP262-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.31Float
941CP262-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.31Float
942CP262-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.31Float%
943CP262-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.31Float%
944CP262-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.31Float
945CP262-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.31String
946CP262-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).31Float%
947CP262-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.31Float%
948CP262-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.31Float%
949CP262-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.31Float%
950CP262-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.31Float%
951CP262-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.31Float%
952CP262-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.31Float%
953CP262-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.31Float%
954CP262-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.31Float%
955CP262-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.31Float%
956CP262-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.31Float%
957CP262-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.31Float%
958CP262-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.31Float%
959CP262-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.31Float%
960CP262-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.31Float%
961CP262-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.31Float%
962CP262-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.31Float%
963CP262-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.31Float%
964ECU-Outcome32Outcome
965ECU-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.32String
966ECU-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.32FloatμM
967ECU-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.32Float%
968ECU-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.32String
969ECU-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.32String
970ECU-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).32Float
971ECU-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.32Float
972ECU-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.32Float
973ECU-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.32Float%
974ECU-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.32Float%
975ECU-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.32Float
976ECU-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.32String
977ECU-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).32Float%
978ECU-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.32Float%
979ECU-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.32Float%
980ECU-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.32Float%
981ECU-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.32Float%
982ECU-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.32Float%
983ECU-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.32Float%
984ECU-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.32Float%
985ECU-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.32Float%
986ECU-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.32Float%
987ECU-Activity at 0.107 uM (0.106749μM**)% Activity at given concentration.32Float%
988ECU-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.32Float%
989ECU-Activity at 0.534 uM (0.533744μM**)% Activity at given concentration.32Float%
990ECU-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.32Float%
991ECU-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.32Float%
992ECU-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.32Float%
993ECU-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.32Float%
994ECU-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.32Float%
995PC26-Outcome33Outcome
996PC26-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.33String
997PC26-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.33FloatμM
998PC26-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.33Float%
999PC26-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.33String
1000PC26-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.33String
1001PC26-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).33Float
1002PC26-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.33Float
1003PC26-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.33Float
1004PC26-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.33Float%
1005PC26-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.33Float%
1006PC26-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.33Float
1007PC26-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.33String
1008PC26-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).33Float%
1009PC26-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.33Float%
1010PC26-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.33Float%
1011PC26-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.33Float%
1012PC26-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.33Float%
1013PC26-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.33Float%
1014PC26-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.33Float%
1015PC26-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.33Float%
1016PC26-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.33Float%
1017PC26-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.33Float%
1018PC26-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.33Float%
1019PC26-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.33Float%
1020PC26-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.33Float%
1021PC26-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.33Float%
1022PC26-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.33Float%
1023PC26-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.33Float%
1024PC26-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.33Float%
1025PC26-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.33Float%
1026ATS95-Outcome34Outcome
1027ATS95-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.34String
1028ATS95-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.34FloatμM
1029ATS95-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.34Float%
1030ATS95-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.34String
1031ATS95-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.34String
1032ATS95-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).34Float
1033ATS95-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.34Float
1034ATS95-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.34Float
1035ATS95-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.34Float%
1036ATS95-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.34Float%
1037ATS95-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.34Float
1038ATS95-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.34String
1039ATS95-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).34Float%
1040ATS95-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.34Float%
1041ATS95-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.34Float%
1042ATS95-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.34Float%
1043ATS95-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.34Float%
1044ATS95-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.34Float%
1045ATS95-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.34Float%
1046ATS95-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.34Float%
1047ATS95-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.34Float%
1048ATS95-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.34Float%
1049ATS95-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.34Float%
1050ATS95-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.34Float%
1051ATS95-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.34Float%
1052ATS95-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.34Float%
1053ATS95-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.34Float%
1054ATS95-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.34Float%
1055ATS95-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.34Float%
1056ATS95-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.34Float%
1057PAD-Outcome35Outcome
1058PAD-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.35String
1059PAD-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.35FloatμM
1060PAD-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.35Float%
1061PAD-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.35String
1062PAD-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.35String
1063PAD-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).35Float
1064PAD-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.35Float
1065PAD-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.35Float
1066PAD-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.35Float%
1067PAD-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.35Float%
1068PAD-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.35Float
1069PAD-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.35String
1070PAD-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).35Float%
1071PAD-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.35Float%
1072PAD-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.35Float%
1073PAD-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.35Float%
1074PAD-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.35Float%
1075PAD-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.35Float%
1076PAD-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.35Float%
1077PAD-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.35Float%
1078PAD-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.35Float%
1079PAD-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.35Float%
1080PAD-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.35Float%
1081PAD-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.35Float%
1082PAD-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.35Float%
1083PAD-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.35Float%
1084PAD-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.35Float%
1085PAD-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.35Float%
1086PAD-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.35Float%
1087PAD-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.35Float%
1088CP269-Outcome36Outcome
1089CP269-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.36String
1090CP269-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.36FloatμM
1091CP269-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.36Float%
1092CP269-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.36String
1093CP269-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.36String
1094CP269-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).36Float
1095CP269-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.36Float
1096CP269-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.36Float
1097CP269-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.36Float%
1098CP269-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.36Float%
1099CP269-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.36Float
1100CP269-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.36String
1101CP269-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).36Float%
1102CP269-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.36Float%
1103CP269-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.36Float%
1104CP269-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.36Float%
1105CP269-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.36Float%
1106CP269-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.36Float%
1107CP269-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.36Float%
1108CP269-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.36Float%
1109CP269-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.36Float%
1110CP269-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.36Float%
1111CP269-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.36Float%
1112CP269-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.36Float%
1113CP269-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.36Float%
1114CP269-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.36Float%
1115CP269-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.36Float%
1116CP269-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.36Float%
1117CP269-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.36Float%
1118CP269-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.36Float%
1119456-Outcome37Outcome
1120456-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.37String
1121456-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.37FloatμM
1122456-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.37Float%
1123456-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.37String
1124456-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.37String
1125456-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).37Float
1126456-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.37Float
1127456-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.37Float
1128456-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.37Float%
1129456-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.37Float%
1130456-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.37Float
1131456-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.37String
1132456-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).37Float%
1133456-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.37Float%
1134456-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.37Float%
1135456-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.37Float%
1136456-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.37Float%
1137456-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.37Float%
1138456-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.37Float%
1139456-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.37Float%
1140456-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.37Float%
1141456-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.37Float%
1142456-Activity at 0.107 uM (0.106749μM**)% Activity at given concentration.37Float%
1143456-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.37Float%
1144456-Activity at 0.534 uM (0.533744μM**)% Activity at given concentration.37Float%
1145456-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.37Float%
1146456-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.37Float%
1147456-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.37Float%
1148456-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.37Float%
1149456-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.37Float%
1150CP325-Outcome38Outcome
1151CP325-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.38String
1152CP325-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.38FloatμM
1153CP325-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.38Float%
1154CP325-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.38String
1155CP325-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.38String
1156CP325-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).38Float
1157CP325-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.38Float
1158CP325-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.38Float
1159CP325-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.38Float%
1160CP325-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.38Float%
1161CP325-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.38Float
1162CP325-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.38String
1163CP325-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).38Float%
1164CP325-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.38Float%
1165CP325-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.38Float%
1166CP325-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.38Float%
1167CP325-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.38Float%
1168CP325-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.38Float%
1169CP325-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.38Float%
1170CP325-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.38Float%
1171CP325-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.38Float%
1172CP325-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.38Float%
1173CP325-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.38Float%
1174CP325-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.38Float%
1175CP325-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.38Float%
1176CP325-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.38Float%
1177CP325-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.38Float%
1178CP325-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.38Float%
1179CP325-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.38Float%
1180CP325-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.38Float%
1181P93_24-Outcome39Outcome
1182P93_24-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.39String
1183P93_24-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.39FloatμM
1184P93_24-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.39Float%
1185P93_24-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.39String
1186P93_24-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.39String
1187P93_24-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).39Float
1188P93_24-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.39Float
1189P93_24-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.39Float
1190P93_24-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.39Float%
1191P93_24-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.39Float%
1192P93_24-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.39Float
1193P93_24-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.39String
1194P93_24-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).39Float%
1195P93_24-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.39Float%
1196P93_24-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.39Float%
1197P93_24-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.39Float%
1198P93_24-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.39Float%
1199P93_24-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.39Float%
1200P93_24-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.39Float%
1201P93_24-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.39Float%
1202P93_24-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.39Float%
1203P93_24-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.39Float%
1204P93_24-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.39Float%
1205P93_24-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.39Float%
1206P93_24-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.39Float%
1207P93_24-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.39Float%
1208P93_24-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.39Float%
1209P93_24-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.39Float%
1210P93_24-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.39Float%
1211P93_24-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.39Float%
1212C2A-Outcome40Outcome
1213C2A-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.40String
1214C2A-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.40FloatμM
1215C2A-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.40Float%
1216C2A-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.40String
1217C2A-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.40String
1218C2A-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).40Float
1219C2A-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.40Float
1220C2A-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.40Float
1221C2A-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.40Float%
1222C2A-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.40Float%
1223C2A-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.40Float
1224C2A-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.40String
1225C2A-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).40Float%
1226C2A-Activity at 0.0000822414 uM (8.22414e-05μM**)% Activity at given concentration.40Float%
1227C2A-Activity at 0.0001738940 uM (0.000173894μM**)% Activity at given concentration.40Float%
1228C2A-Activity at 0.0003676724 uM (0.000367672μM**)% Activity at given concentration.40Float%
1229C2A-Activity at 0.0008408640 uM (0.000840864μM**)% Activity at given concentration.40Float%
1230C2A-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.40Float%
1231C2A-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.40Float%
1232C2A-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.40Float%
1233C2A-Activity at 0.021 uM (0.0205517μM**)% Activity at given concentration.40Float%
1234C2A-Activity at 0.023 uM (0.0229885μM**)% Activity at given concentration.40Float%
1235C2A-Activity at 0.047 uM (0.0472785μM**)% Activity at given concentration.40Float%
1236C2A-Activity at 0.103 uM (0.102759μM**)% Activity at given concentration.40Float%
1237C2A-Activity at 0.230 uM (0.229856μM**)% Activity at given concentration.40Float%
1238C2A-Activity at 0.529 uM (0.528537μM**)% Activity at given concentration.40Float%
1239C2A-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.40Float%
1240C2A-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.40Float%
1241C2A-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.40Float%
1242C2A-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.40Float%
1243C2A-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.40Float%
1244CP329-Outcome41Outcome
1245CP329-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.41String
1246CP329-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.41FloatμM
1247CP329-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.41Float%
1248CP329-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.41String
1249CP329-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.41String
1250CP329-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).41Float
1251CP329-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.41Float
1252CP329-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.41Float
1253CP329-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.41Float%
1254CP329-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.41Float%
1255CP329-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.41Float
1256CP329-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.41String
1257CP329-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).41Float%
1258CP329-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.41Float%
1259CP329-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.41Float%
1260CP329-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.41Float%
1261CP329-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.41Float%
1262CP329-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.41Float%
1263CP329-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.41Float%
1264CP329-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.41Float%
1265CP329-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.41Float%
1266CP329-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.41Float%
1267CP329-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.41Float%
1268CP329-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.41Float%
1269CP329-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.41Float%
1270CP329-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.41Float%
1271CP329-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.41Float%
1272CP329-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.41Float%
1273CP329-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.41Float%
1274CP329-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.41Float%
1275SC27B-Outcome42Outcome
1276SC27B-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.42String
1277SC27B-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.42FloatμM
1278SC27B-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.42Float%
1279SC27B-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.42String
1280SC27B-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.42String
1281SC27B-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).42Float
1282SC27B-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.42Float
1283SC27B-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.42Float
1284SC27B-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.42Float%
1285SC27B-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.42Float%
1286SC27B-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.42Float
1287SC27B-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.42String
1288SC27B-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).42Float%
1289SC27B-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.42Float%
1290SC27B-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.42Float%
1291SC27B-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.42Float%
1292SC27B-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.42Float%
1293SC27B-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.42Float%
1294SC27B-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.42Float%
1295SC27B-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.42Float%
1296SC27B-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.42Float%
1297SC27B-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.42Float%
1298SC27B-Activity at 0.107 uM (0.106749μM**)% Activity at given concentration.42Float%
1299SC27B-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.42Float%
1300SC27B-Activity at 0.534 uM (0.533744μM**)% Activity at given concentration.42Float%
1301SC27B-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.42Float%
1302SC27B-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.42Float%
1303SC27B-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.42Float%
1304SC27B-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.42Float%
1305SC27B-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.42Float%
1306CP256-Outcome43Outcome
1307CP256-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.43String
1308CP256-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.43FloatμM
1309CP256-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.43Float%
1310CP256-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.43String
1311CP256-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.43String
1312CP256-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).43Float
1313CP256-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.43Float
1314CP256-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.43Float
1315CP256-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.43Float%
1316CP256-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.43Float%
1317CP256-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.43Float
1318CP256-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.43String
1319CP256-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).43Float%
1320CP256-Activity at 0.0000822400 uM (8.224e-05μM**)% Activity at given concentration.43Float%
1321CP256-Activity at 0.0001738769 uM (0.000173877μM**)% Activity at given concentration.43Float%
1322CP256-Activity at 0.0003677000 uM (0.0003677μM**)% Activity at given concentration.43Float%
1323CP256-Activity at 0.0008408811 uM (0.000840881μM**)% Activity at given concentration.43Float%
1324CP256-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.43Float%
1325CP256-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.43Float%
1326CP256-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.43Float%
1327CP256-Activity at 0.021 uM (0.02055μM**)% Activity at given concentration.43Float%
1328CP256-Activity at 0.023 uM (0.02299μM**)% Activity at given concentration.43Float%
1329CP256-Activity at 0.047 uM (0.0472789μM**)% Activity at given concentration.43Float%
1330CP256-Activity at 0.103 uM (0.1028μM**)% Activity at given concentration.43Float%
1331CP256-Activity at 0.230 uM (0.229875μM**)% Activity at given concentration.43Float%
1332CP256-Activity at 0.528 uM (0.528494μM**)% Activity at given concentration.43Float%
1333CP256-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.43Float%
1334CP256-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.43Float%
1335CP256-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.43Float%
1336CP256-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.43Float%
1337CP256-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.43Float%
1338CP250-Outcome44Outcome
1339CP250-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.44String
1340CP250-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.44FloatμM
1341CP250-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.44Float%
1342CP250-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.44String
1343CP250-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.44String
1344CP250-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).44Float
1345CP250-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.44Float
1346CP250-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.44Float
1347CP250-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.44Float%
1348CP250-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.44Float%
1349CP250-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.44Float
1350CP250-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.44String
1351CP250-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).44Float%
1352CP250-Activity at 0.0000822414 uM (8.22414e-05μM**)% Activity at given concentration.44Float%
1353CP250-Activity at 0.0001738940 uM (0.000173894μM**)% Activity at given concentration.44Float%
1354CP250-Activity at 0.0003676724 uM (0.000367672μM**)% Activity at given concentration.44Float%
1355CP250-Activity at 0.0008408640 uM (0.000840864μM**)% Activity at given concentration.44Float%
1356CP250-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.44Float%
1357CP250-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.44Float%
1358CP250-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.44Float%
1359CP250-Activity at 0.021 uM (0.0205517μM**)% Activity at given concentration.44Float%
1360CP250-Activity at 0.023 uM (0.0229885μM**)% Activity at given concentration.44Float%
1361CP250-Activity at 0.047 uM (0.0472785μM**)% Activity at given concentration.44Float%
1362CP250-Activity at 0.103 uM (0.102759μM**)% Activity at given concentration.44Float%
1363CP250-Activity at 0.230 uM (0.229856μM**)% Activity at given concentration.44Float%
1364CP250-Activity at 0.529 uM (0.528537μM**)% Activity at given concentration.44Float%
1365CP250-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.44Float%
1366CP250-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.44Float%
1367CP250-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.44Float%
1368CP250-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.44Float%
1369CP250-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.44Float%
1370CP215-Outcome45Outcome
1371CP215-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.45String
1372CP215-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.45FloatμM
1373CP215-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.45Float%
1374CP215-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.45String
1375CP215-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.45String
1376CP215-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).45Float
1377CP215-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.45Float
1378CP215-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.45Float
1379CP215-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.45Float%
1380CP215-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.45Float%
1381CP215-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.45Float
1382CP215-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.45String
1383CP215-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).45Float%
1384CP215-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.45Float%
1385CP215-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.45Float%
1386CP215-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.45Float%
1387CP215-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.45Float%
1388CP215-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.45Float%
1389CP215-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.45Float%
1390CP215-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.45Float%
1391CP215-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.45Float%
1392CP215-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.45Float%
1393CP215-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.45Float%
1394CP215-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.45Float%
1395CP215-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.45Float%
1396CP215-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.45Float%
1397CP215-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.45Float%
1398CP215-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.45Float%
1399CP215-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.45Float%
1400CP215-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.45Float%
1401224-Outcome46Outcome
1402224-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.46String
1403224-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.46FloatμM
1404224-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.46Float%
1405224-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.46String
1406224-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.46String
1407224-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).46Float
1408224-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.46Float
1409224-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.46Float
1410224-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.46Float%
1411224-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.46Float%
1412224-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.46Float
1413224-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.46String
1414224-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).46Float%
1415224-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.46Float%
1416224-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.46Float%
1417224-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.46Float%
1418224-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.46Float%
1419224-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.46Float%
1420224-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.46Float%
1421224-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.46Float%
1422224-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.46Float%
1423224-Activity at 0.047 uM (0.0472851μM**)% Activity at given concentration.46Float%
1424224-Activity at 0.103 uM (0.102874μM**)% Activity at given concentration.46Float%
1425224-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.46Float%
1426224-Activity at 0.529 uM (0.528832μM**)% Activity at given concentration.46Float%
1427224-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.46Float%
1428224-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.46Float%
1429224-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.46Float%
1430224-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.46Float%
1431224-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.46Float%
1432CP252-Outcome47Outcome
1433CP252-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.47String
1434CP252-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.47FloatμM
1435CP252-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.47Float%
1436CP252-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.47String
1437CP252-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.47String
1438CP252-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).47Float
1439CP252-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.47Float
1440CP252-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.47Float
1441CP252-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.47Float%
1442CP252-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.47Float%
1443CP252-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.47Float
1444CP252-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.47String
1445CP252-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).47Float%
1446CP252-Activity at 0.0000822400 uM (8.224e-05μM**)% Activity at given concentration.47Float%
1447CP252-Activity at 0.0001738769 uM (0.000173877μM**)% Activity at given concentration.47Float%
1448CP252-Activity at 0.0003677000 uM (0.0003677μM**)% Activity at given concentration.47Float%
1449CP252-Activity at 0.0008408811 uM (0.000840881μM**)% Activity at given concentration.47Float%
1450CP252-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.47Float%
1451CP252-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.47Float%
1452CP252-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.47Float%
1453CP252-Activity at 0.021 uM (0.02055μM**)% Activity at given concentration.47Float%
1454CP252-Activity at 0.023 uM (0.02299μM**)% Activity at given concentration.47Float%
1455CP252-Activity at 0.047 uM (0.0472789μM**)% Activity at given concentration.47Float%
1456CP252-Activity at 0.103 uM (0.1028μM**)% Activity at given concentration.47Float%
1457CP252-Activity at 0.230 uM (0.229875μM**)% Activity at given concentration.47Float%
1458CP252-Activity at 0.528 uM (0.528494μM**)% Activity at given concentration.47Float%
1459CP252-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.47Float%
1460CP252-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.47Float%
1461CP252-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.47Float%
1462CP252-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.47Float%
1463CP252-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.47Float%
1464CP217-Outcome48Outcome
1465CP217-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.48String
1466CP217-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.48FloatμM
1467CP217-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.48Float%
1468CP217-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.48String
1469CP217-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.48String
1470CP217-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).48Float
1471CP217-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.48Float
1472CP217-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.48Float
1473CP217-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.48Float%
1474CP217-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.48Float%
1475CP217-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.48Float
1476CP217-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.48String
1477CP217-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).48Float%
1478CP217-Activity at 0.0000822400 uM (8.224e-05μM**)% Activity at given concentration.48Float%
1479CP217-Activity at 0.0001738769 uM (0.000173877μM**)% Activity at given concentration.48Float%
1480CP217-Activity at 0.0003677000 uM (0.0003677μM**)% Activity at given concentration.48Float%
1481CP217-Activity at 0.0008408811 uM (0.000840881μM**)% Activity at given concentration.48Float%
1482CP217-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.48Float%
1483CP217-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.48Float%
1484CP217-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.48Float%
1485CP217-Activity at 0.021 uM (0.02055μM**)% Activity at given concentration.48Float%
1486CP217-Activity at 0.023 uM (0.02299μM**)% Activity at given concentration.48Float%
1487CP217-Activity at 0.046 uM (0.04598μM**)% Activity at given concentration.48Float%
1488CP217-Activity at 0.103 uM (0.1028μM**)% Activity at given concentration.48Float%
1489CP217-Activity at 0.230 uM (0.2299μM**)% Activity at given concentration.48Float%
1490CP217-Activity at 0.543 uM (0.543398μM**)% Activity at given concentration.48Float%
1491CP217-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.48Float%
1492CP217-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.48Float%
1493CP217-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.48Float%
1494CP217-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.48Float%
1495CP217-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.48Float%
1496FAB9-Outcome49Outcome
1497FAB9-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.49String
1498FAB9-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.49FloatμM
1499FAB9-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.49Float%
1500FAB9-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.49String
1501FAB9-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.49String
1502FAB9-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).49Float
1503FAB9-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.49Float
1504FAB9-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.49Float
1505FAB9-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.49Float%
1506FAB9-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.49Float%
1507FAB9-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.49Float
1508FAB9-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.49String
1509FAB9-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).49Float%
1510FAB9-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.49Float%
1511FAB9-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.49Float%
1512FAB9-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.49Float%
1513FAB9-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.49Float%
1514FAB9-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.49Float%
1515FAB9-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.49Float%
1516FAB9-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.49Float%
1517FAB9-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.49Float%
1518FAB9-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.49Float%
1519FAB9-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.49Float%
1520FAB9-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.49Float%
1521FAB9-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.49Float%
1522FAB9-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.49Float%
1523FAB9-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.49Float%
1524FAB9-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.49Float%
1525FAB9-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.49Float%
1526FAB9-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.49Float%
1527CP211-Outcome50Outcome
1528CP211-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.50String
1529CP211-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.50FloatμM
1530CP211-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.50Float%
1531CP211-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.50String
1532CP211-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.50String
1533CP211-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).50Float
1534CP211-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.50Float
1535CP211-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.50Float
1536CP211-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.50Float%
1537CP211-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.50Float%
1538CP211-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.50Float
1539CP211-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.50String
1540CP211-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).50Float%
1541CP211-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.50Float%
1542CP211-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.50Float%
1543CP211-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.50Float%
1544CP211-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.50Float%
1545CP211-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.50Float%
1546CP211-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.50Float%
1547CP211-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.50Float%
1548CP211-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.50Float%
1549CP211-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.50Float%
1550CP211-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.50Float%
1551CP211-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.50Float%
1552CP211-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.50Float%
1553CP211-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.50Float%
1554CP211-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.50Float%
1555CP211-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.50Float%
1556CP211-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.50Float%
1557CP211-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.50Float%
1558PC15-Outcome51Outcome
1559PC15-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.51String
1560PC15-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.51FloatμM
1561PC15-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.51Float%
1562PC15-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.51String
1563PC15-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.51String
1564PC15-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).51Float
1565PC15-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.51Float
1566PC15-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.51Float
1567PC15-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.51Float%
1568PC15-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.51Float%
1569PC15-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.51Float
1570PC15-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.51String
1571PC15-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).51Float%
1572PC15-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.51Float%
1573PC15-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.51Float%
1574PC15-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.51Float%
1575PC15-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.51Float%
1576PC15-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.51Float%
1577PC15-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.51Float%
1578PC15-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.51Float%
1579PC15-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.51Float%
1580PC15-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.51Float%
1581PC15-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.51Float%
1582PC15-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.51Float%
1583PC15-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.51Float%
1584PC15-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.51Float%
1585PC15-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.51Float%
1586PC15-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.51Float%
1587PC15-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.51Float%
1588PC15-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.51Float%
1589N140-Outcome52Outcome
1590N140-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.52String
1591N140-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.52FloatμM
1592N140-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.52Float%
1593N140-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.52String
1594N140-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.52String
1595N140-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).52Float
1596N140-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.52Float
1597N140-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.52Float
1598N140-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.52Float%
1599N140-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.52Float%
1600N140-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.52Float
1601N140-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.52String
1602N140-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).52Float%
1603N140-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.52Float%
1604N140-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.52Float%
1605N140-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.52Float%
1606N140-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.52Float%
1607N140-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.52Float%
1608N140-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.52Float%
1609N140-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.52Float%
1610N140-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.52Float%
1611N140-Activity at 0.047 uM (0.0472851μM**)% Activity at given concentration.52Float%
1612N140-Activity at 0.103 uM (0.102874μM**)% Activity at given concentration.52Float%
1613N140-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.52Float%
1614N140-Activity at 0.529 uM (0.528832μM**)% Activity at given concentration.52Float%
1615N140-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.52Float%
1616N140-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.52Float%
1617N140-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.52Float%
1618N140-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.52Float%
1619N140-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.52Float%
1620DIV17-Outcome53Outcome
1621DIV17-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.53String
1622DIV17-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.53FloatμM
1623DIV17-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.53Float%
1624DIV17-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.53String
1625DIV17-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.53String
1626DIV17-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).53Float
1627DIV17-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.53Float
1628DIV17-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.53Float
1629DIV17-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.53Float%
1630DIV17-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.53Float%
1631DIV17-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.53Float
1632DIV17-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.53String
1633DIV17-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).53Float%
1634DIV17-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.53Float%
1635DIV17-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.53Float%
1636DIV17-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.53Float%
1637DIV17-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.53Float%
1638DIV17-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.53Float%
1639DIV17-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.53Float%
1640DIV17-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.53Float%
1641DIV17-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.53Float%
1642DIV17-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.53Float%
1643DIV17-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.53Float%
1644DIV17-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.53Float%
1645DIV17-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.53Float%
1646DIV17-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.53Float%
1647DIV17-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.53Float%
1648DIV17-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.53Float%
1649DIV17-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.53Float%
1650DIV17-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.53Float%
1651AA1029-Outcome54Outcome
1652AA1029-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.54String
1653AA1029-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.54FloatμM
1654AA1029-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.54Float%
1655AA1029-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.54String
1656AA1029-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.54String
1657AA1029-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).54Float
1658AA1029-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.54Float
1659AA1029-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.54Float
1660AA1029-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.54Float%
1661AA1029-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.54Float%
1662AA1029-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.54Float
1663AA1029-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.54String
1664AA1029-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).54Float%
1665AA1029-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.54Float%
1666AA1029-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.54Float%
1667AA1029-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.54Float%
1668AA1029-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.54Float%
1669AA1029-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.54Float%
1670AA1029-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.54Float%
1671AA1029-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.54Float%
1672AA1029-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.54Float%
1673AA1029-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.54Float%
1674AA1029-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.54Float%
1675AA1029-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.54Float%
1676AA1029-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.54Float%
1677AA1029-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.54Float%
1678AA1029-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.54Float%
1679AA1029-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.54Float%
1680AA1029-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.54Float%
1681AA1029-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.54Float%
1682DIV14-Outcome55Outcome
1683DIV14-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.55String
1684DIV14-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.55FloatμM
1685DIV14-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.55Float%
1686DIV14-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.55String
1687DIV14-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.55String
1688DIV14-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).55Float
1689DIV14-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.55Float
1690DIV14-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.55Float
1691DIV14-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.55Float%
1692DIV14-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.55Float%
1693DIV14-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.55Float
1694DIV14-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.55String
1695DIV14-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).55Float%
1696DIV14-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.55Float%
1697DIV14-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.55Float%
1698DIV14-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.55Float%
1699DIV14-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.55Float%
1700DIV14-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.55Float%
1701DIV14-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.55Float%
1702DIV14-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.55Float%
1703DIV14-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.55Float%
1704DIV14-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.55Float%
1705DIV14-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.55Float%
1706DIV14-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.55Float%
1707DIV14-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.55Float%
1708DIV14-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.55Float%
1709DIV14-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.55Float%
1710DIV14-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.55Float%
1711DIV14-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.55Float%
1712DIV14-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.55Float%
1713TAB165-Outcome56Outcome
1714TAB165-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.56String
1715TAB165-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.56FloatμM
1716TAB165-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.56Float%
1717TAB165-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.56String
1718TAB165-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.56String
1719TAB165-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).56Float
1720TAB165-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.56Float
1721TAB165-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.56Float
1722TAB165-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.56Float%
1723TAB165-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.56Float%
1724TAB165-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.56Float
1725TAB165-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.56String
1726TAB165-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).56Float%
1727TAB165-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.56Float%
1728TAB165-Activity at 0.0001706389 uM (0.000170639μM**)% Activity at given concentration.56Float%
1729TAB165-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.56Float%
1730TAB165-Activity at 0.0008531946 uM (0.000853195μM**)% Activity at given concentration.56Float%
1731TAB165-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.56Float%
1732TAB165-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.56Float%
1733TAB165-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.56Float%
1734TAB165-Activity at 0.021 uM (0.0213299μM**)% Activity at given concentration.56Float%
1735TAB165-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.56Float%
1736TAB165-Activity at 0.107 uM (0.106749μM**)% Activity at given concentration.56Float%
1737TAB165-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.56Float%
1738TAB165-Activity at 0.534 uM (0.533744μM**)% Activity at given concentration.56Float%
1739TAB165-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.56Float%
1740TAB165-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.56Float%
1741TAB165-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.56Float%
1742TAB165-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.56Float%
1743TAB165-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.56Float%
1744ICS-Outcome57Outcome
1745ICS-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.57String
1746ICS-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.57FloatμM
1747ICS-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.57Float%
1748ICS-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.57String
1749ICS-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.57String
1750ICS-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).57Float
1751ICS-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.57Float
1752ICS-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.57Float
1753ICS-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.57Float%
1754ICS-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.57Float%
1755ICS-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.57Float
1756ICS-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.57String
1757ICS-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).57Float%
1758ICS-Activity at 0.0000367800 uM (3.678e-05μM**)% Activity at given concentration.57Float%
1759ICS-Activity at 0.0001706587 uM (0.000170659μM**)% Activity at given concentration.57Float%
1760ICS-Activity at 0.0003678000 uM (0.0003678μM**)% Activity at given concentration.57Float%
1761ICS-Activity at 0.0008533627 uM (0.000853363μM**)% Activity at given concentration.57Float%
1762ICS-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.57Float%
1763ICS-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.57Float%
1764ICS-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.57Float%
1765ICS-Activity at 0.021 uM (0.0213331μM**)% Activity at given concentration.57Float%
1766ICS-Activity at 0.046 uM (0.04598μM**)% Activity at given concentration.57Float%
1767ICS-Activity at 0.107 uM (0.106685μM**)% Activity at given concentration.57Float%
1768ICS-Activity at 0.230 uM (0.2299μM**)% Activity at given concentration.57Float%
1769ICS-Activity at 0.533 uM (0.533347μM**)% Activity at given concentration.57Float%
1770ICS-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.57Float%
1771ICS-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.57Float%
1772ICS-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.57Float%
1773ICS-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.57Float%
1774ICS-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.57Float%
1775CP260-Outcome58Outcome
1776CP260-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.58String
1777CP260-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.58FloatμM
1778CP260-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.58Float%
1779CP260-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.58String
1780CP260-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.58String
1781CP260-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).58Float
1782CP260-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.58Float
1783CP260-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.58Float
1784CP260-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.58Float%
1785CP260-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.58Float%
1786CP260-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.58Float
1787CP260-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.58String
1788CP260-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).58Float%
1789CP260-Activity at 0.0000367800 uM (3.678e-05μM**)% Activity at given concentration.58Float%
1790CP260-Activity at 0.0001706587 uM (0.000170659μM**)% Activity at given concentration.58Float%
1791CP260-Activity at 0.0003678000 uM (0.0003678μM**)% Activity at given concentration.58Float%
1792CP260-Activity at 0.0008533627 uM (0.000853363μM**)% Activity at given concentration.58Float%
1793CP260-Activity at 0.00184 uM (0.001839μM**)% Activity at given concentration.58Float%
1794CP260-Activity at 0.00427 uM (0.00426662μM**)% Activity at given concentration.58Float%
1795CP260-Activity at 0.00919 uM (0.009195μM**)% Activity at given concentration.58Float%
1796CP260-Activity at 0.021 uM (0.0213331μM**)% Activity at given concentration.58Float%
1797CP260-Activity at 0.046 uM (0.04598μM**)% Activity at given concentration.58Float%
1798CP260-Activity at 0.107 uM (0.106685μM**)% Activity at given concentration.58Float%
1799CP260-Activity at 0.230 uM (0.2299μM**)% Activity at given concentration.58Float%
1800CP260-Activity at 0.533 uM (0.533347μM**)% Activity at given concentration.58Float%
1801CP260-Activity at 1.149 uM (1.149μM**)% Activity at given concentration.58Float%
1802CP260-Activity at 2.667 uM (2.66689μM**)% Activity at given concentration.58Float%
1803CP260-Activity at 5.747 uM (5.747μM**)% Activity at given concentration.58Float%
1804CP260-Activity at 12.84 uM (12.84μM**)% Activity at given concentration.58Float%
1805CP260-Activity at 28.74 uM (28.74μM**)% Activity at given concentration.58Float%
1806CP315-Outcome59Outcome
1807CP315-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.59String
1808CP315-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.59FloatμM
1809CP315-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.59Float%
1810CP315-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.59String
1811CP315-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.59String
1812CP315-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).59Float
1813CP315-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.59Float
1814CP315-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.59Float
1815CP315-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.59Float%
1816CP315-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.59Float%
1817CP315-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.59Float
1818CP315-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.59String
1819CP315-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).59Float%
1820CP315-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.59Float%
1821CP315-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.59Float%
1822CP315-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.59Float%
1823CP315-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.59Float%
1824CP315-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.59Float%
1825CP315-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.59Float%
1826CP315-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.59Float%
1827CP315-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.59Float%
1828CP315-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.59Float%
1829CP315-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.59Float%
1830CP315-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.59Float%
1831CP315-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.59Float%
1832CP315-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.59Float%
1833CP315-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.59Float%
1834CP315-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.59Float%
1835CP315-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.59Float%
1836CP315-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.59Float%
1837CP297-Outcome60Outcome
1838CP297-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.60String
1839CP297-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.60FloatμM
1840CP297-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.60Float%
1841CP297-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.60String
1842CP297-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.60String
1843CP297-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).60Float
1844CP297-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.60Float
1845CP297-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.60Float
1846CP297-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.60Float%
1847CP297-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.60Float%
1848CP297-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.60Float
1849CP297-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.60String
1850CP297-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).60Float%
1851CP297-Activity at 0.0000368000 uM (3.68e-05μM**)% Activity at given concentration.60Float%
1852CP297-Activity at 0.0001704127 uM (0.000170413μM**)% Activity at given concentration.60Float%
1853CP297-Activity at 0.0003680000 uM (0.000368μM**)% Activity at given concentration.60Float%
1854CP297-Activity at 0.0008534482 uM (0.000853448μM**)% Activity at given concentration.60Float%
1855CP297-Activity at 0.00184 uM (0.00184μM**)% Activity at given concentration.60Float%
1856CP297-Activity at 0.00427 uM (0.00426724μM**)% Activity at given concentration.60Float%
1857CP297-Activity at 0.00920 uM (0.0092μM**)% Activity at given concentration.60Float%
1858CP297-Activity at 0.021 uM (0.0213708μM**)% Activity at given concentration.60Float%
1859CP297-Activity at 0.046 uM (0.046μM**)% Activity at given concentration.60Float%
1860CP297-Activity at 0.107 uM (0.106854μM**)% Activity at given concentration.60Float%
1861CP297-Activity at 0.230 uM (0.23μM**)% Activity at given concentration.60Float%
1862CP297-Activity at 0.534 uM (0.533578μM**)% Activity at given concentration.60Float%
1863CP297-Activity at 1.150 uM (1.15μM**)% Activity at given concentration.60Float%
1864CP297-Activity at 2.666 uM (2.66634μM**)% Activity at given concentration.60Float%
1865CP297-Activity at 5.750 uM (5.75μM**)% Activity at given concentration.60Float%
1866CP297-Activity at 12.80 uM (12.8μM**)% Activity at given concentration.60Float%
1867CP297-Activity at 28.70 uM (28.7μM**)% Activity at given concentration.60Float%
1868JCK-Outcome61Outcome
1869JCK-PhenotypeIndicates type of activity observed: inhibitor, activator, fluorescent, cytotoxic, inactive, or inconclusive.61String
1870JCK-PotencyConcentration at which compound exhibits half-maximal efficacy, AC50. Extrapolated AC50s also include the highest efficacy observed and the concentration of compound at which it was observed.61FloatμM
1871JCK-EfficacyMaximal efficacy of compound, reported as a percentage of control. These values are estimated based on fits of the Hill equation to the dose-response curves.61Float%
1872JCK-Analysis CommentAnnotation/notes on a particular compound's data or its analysis.61String
1873JCK-Curve_DescriptionA description of dose-response curve quality. A complete curve has two observed asymptotes; a partial curve may not have attained its second asymptote at the highest concentration tested. High efficacy curves exhibit efficacy greater than 80% of control. Partial efficacies are statistically significant, but below 80% of control.61String
1874JCK-Fit_LogAC50The logarithm of the AC50 from a fit of the data to the Hill equation (calculated based on Molar Units).61Float
1875JCK-Fit_HillSlopeThe Hill slope from a fit of the data to the Hill equation.61Float
1876JCK-Fit_R2R^2 fit value of the curve. Closer to 1.0 equates to better Hill equation fit.61Float
1877JCK-Fit_InfiniteActivityThe asymptotic efficacy from a fit of the data to the Hill equation.61Float%
1878JCK-Fit_ZeroActivityEfficacy at zero concentration of compound from a fit of the data to the Hill equation.61Float%
1879JCK-Fit_CurveClassNumerical encoding of curve description for the fitted Hill equation.61Float
1880JCK-Excluded_PointsWhich dose-response titration points were excluded from analysis based on outlier analysis. Each number represents whether a titration point was (1) or was not (0) excluded, for the titration series going from smallest to highest compound concentrations.61String
1881JCK-Max_ResponseMaximum activity observed for compound (usually at highest concentration tested).61Float%
1882JCK-Activity at 0.0000367816 uM (3.67816e-05μM**)% Activity at given concentration.61Float%
1883JCK-Activity at 0.0001706787 uM (0.000170679μM**)% Activity at given concentration.61Float%
1884JCK-Activity at 0.0003678161 uM (0.000367816μM**)% Activity at given concentration.61Float%
1885JCK-Activity at 0.0008533935 uM (0.000853393μM**)% Activity at given concentration.61Float%
1886JCK-Activity at 0.00184 uM (0.00183908μM**)% Activity at given concentration.61Float%
1887JCK-Activity at 0.00427 uM (0.00426597μM**)% Activity at given concentration.61Float%
1888JCK-Activity at 0.00920 uM (0.0091954μM**)% Activity at given concentration.61Float%
1889JCK-Activity at 0.021 uM (0.0213338μM**)% Activity at given concentration.61Float%
1890JCK-Activity at 0.046 uM (0.045977μM**)% Activity at given concentration.61Float%
1891JCK-Activity at 0.107 uM (0.106669μM**)% Activity at given concentration.61Float%
1892JCK-Activity at 0.230 uM (0.229885μM**)% Activity at given concentration.61Float%
1893JCK-Activity at 0.533 uM (0.533346μM**)% Activity at given concentration.61Float%
1894JCK-Activity at 1.149 uM (1.14943μM**)% Activity at given concentration.61Float%
1895JCK-Activity at 2.667 uM (2.66673μM**)% Activity at given concentration.61Float%
1896JCK-Activity at 5.747 uM (5.74713μM**)% Activity at given concentration.61Float%
1897JCK-Activity at 12.84 uM (12.8448μM**)% Activity at given concentration.61Float%
1898JCK-Activity at 28.74 uM (28.7356μM**)% Activity at given concentration.61Float%

** Test Concentration. § Panel component ID.

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