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E3 ubiquitin-protein ligase Mdm2 isoform a [H.. [gi:89993689] - Target BioActivity Data
Also known as: E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens].
BioActivity Outcomes:
Active(16700)
 
 
Inactive(534058)
 
 
BioAssay Types:
Screening(550458)
 
 
 
Confirmatory(300)
 
 
 
BioActivity Types:
EC50(280)
 
 
 
IC50(20)
 
 
 
Substance Types:
Chemical(550758)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 550758   Total Pages: 27538   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID17387810]
[CID1000056]
EC50 0.0021E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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2
[SID17510464]
[CID3380837]
IC50_Mean 0.00374Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction in luminescent format [AID504593, Type: confirmatory]
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3
[SID22414387]
[CID6875148]
EC50 0.02E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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4
[SID22414387]
[CID6875148]
Mean Wild-type EC50 0.04E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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5
[SID17506129]
[CID741762]
Mean Wild-type EC50 0.05E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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6
[SID17508313]
[CID741765]
Mean Wild-type EC50 0.06E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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7
[SID17508313]
[CID741765]
EC50 0.07E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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8
[SID11532980]
[CID5455]
Mean Mutant EC50 0.08E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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9
[SID17433488]
[CID2165997]
Mean Wild-type EC50 0.09E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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10
[SID17506129]
[CID741762]
EC50 0.1E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
View
11
[SID26665014]
[CID360474]
Mean Mutant EC50 0.1E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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12
[SID17433488]
[CID2165997]
EC50 0.16E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
View
13
[SID26725306]
[CID23205]
Mean Wild-type EC50 0.18E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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14
[SID11532980]
[CID5455]
EC50 0.18E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
View
15
[SID26665014]
[CID360474]
Mean Wild-type EC50 0.2E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
View
16
[SID26727177]
[CID5703458]
Mean Wild-type EC50 0.22E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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17
[SID17406707]
[CID7285210]
EC50 0.24E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
View
18
[SID26665014]
[CID360474]
EC50 0.26E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
View
19
[SID17414371]
[CID5737516]
EC50 0.27E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
View
20
[SID26664802]
[CID5382674]
Mean Wild-type EC50 0.29E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
View