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E3 ubiquitin-protein ligase Mdm2 isoform a [H.. [gi:89993689] - Target BioActivity Data
Also known as: E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens].
BioActivity Outcomes:
Active(16700)
 
 
Inactive(534058)
 
 
BioAssay Types:
Screening(550458)
 
 
 
Confirmatory(300)
 
 
 
BioActivity Types:
EC50(280)
 
 
 
IC50(20)
 
 
 
Substance Types:
Chemical(550758)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 550758   Total Pages: 11016   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID17387810]
[CID1000056]
EC50 0.0021E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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2
[SID17510464]
[CID3380837]
IC50_Mean 0.00374Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction in luminescent format [AID504593, Type: confirmatory]
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3
[SID22414387]
[CID6875148]
EC50 0.02E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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4
[SID22414387]
[CID6875148]
Mean Wild-type EC50 0.04E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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5
[SID17506129]
[CID741762]
Mean Wild-type EC50 0.05E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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6
[SID17508313]
[CID741765]
Mean Wild-type EC50 0.06E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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7
[SID17508313]
[CID741765]
EC50 0.07E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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8
[SID11532980]
[CID5455]
Mean Mutant EC50 0.08E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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9
[SID17433488]
[CID2165997]
Mean Wild-type EC50 0.09E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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10
[SID17506129]
[CID741762]
EC50 0.1E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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11
[SID26665014]
[CID360474]
Mean Mutant EC50 0.1E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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12
[SID17433488]
[CID2165997]
EC50 0.16E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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13
[SID26725306]
[CID23205]
Mean Wild-type EC50 0.18E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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14
[SID11532980]
[CID5455]
EC50 0.18E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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15
[SID26665014]
[CID360474]
Mean Wild-type EC50 0.2E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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16
[SID26727177]
[CID5703458]
Mean Wild-type EC50 0.22E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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17
[SID17406707]
[CID7285210]
EC50 0.24E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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18
[SID26665014]
[CID360474]
EC50 0.26E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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19
[SID17414371]
[CID5737516]
EC50 0.27E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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20
[SID26664802]
[CID5382674]
Mean Wild-type EC50 0.29E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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21
[SID24836573]
[CID2376815]
EC50 0.38E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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22
[SID11532980]
[CID5455]
Mean Wild-type EC50 0.4E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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23
[SID17406707]
[CID7285210]
Mean Wild-type EC50 0.41E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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24
[SID26725306]
[CID23205]
EC50 0.42E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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25
[SID14726177]
[CID3154392]
Mean Wild-type EC50 0.43E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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26
[SID24817414]
[CID1472220]
Mean Mutant EC50 0.46E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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27
[SID24836573]
[CID2376815]
Mean Wild-type EC50 0.48E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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28
[SID24817234]
[CID1472222]
Mean Wild-type EC50 0.54E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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29
[SID24817234]
[CID1472222]
EC50 0.56E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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30
[SID858026]
[CID659383]
EC50 0.56E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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31
[SID26664802]
[CID5382674]
Mean Mutant EC50 0.58E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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32
[SID17433012]
[CID5346526]
Mean Wild-type EC50 0.58E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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33
[SID14729678]
[CID3490047]
Mean Mutant EC50 0.6E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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34
[SID26665082]
[CID5388001]
EC50 0.61E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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35
[SID24817414]
[CID1472220]
EC50 0.62E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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36
[SID24787085]
[CID5733483]
Mean Wild-type EC50 0.72E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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37
[SID22408699]
[CID2423595]
Mean Mutant EC50 0.73E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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38
[SID26664410]
[CID230812]
EC50 0.78E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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39
[SID26665082]
[CID5388001]
Mean Wild-type EC50 0.79E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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40
[SID26726824]
[CID5713202]
Mean Mutant EC50 0.79E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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41
[SID26726913]
[CID5713207]
EC50 0.81E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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42
[SID14729216]
[CID1472225]
Mean Mutant EC50 0.84E3 Ligase_Mutant_Dose Response [AID1442, Type: confirmatory]
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43
[SID14743125]
[CID1883255]
EC50 0.84E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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44
[SID26726824]
[CID5713202]
Mean Wild-type EC50 0.88E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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45
[SID24817414]
[CID1472220]
Mean Wild-type EC50 0.89E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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46
[SID22408699]
[CID2423595]
EC50 0.94E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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47
[SID14729216]
[CID1472225]
EC50 0.96E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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48
[SID26726409]
[CID5713206]
EC50 1E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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49
[SID26665155]
[CID371271]
EC50 1.03E3 Ligase dose-response_384 [AID1394, Type: confirmatory]
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50
[SID26664410]
[CID230812]
Mean Wild-type EC50 1.06E3 Ligase_WT_Dose Response [AID1444, Type: confirmatory]
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