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BioActivity Data for Target methionyl-tRNA synthetase [Trypanosoma brucei.. [gi:71746704]

Also known as: methionyl-tRNA synthetase [Trypanosoma brucei brucei strain 927/4 GUTat10.1].
BioActivity Outcomes:
Active(3757)
 
 
Inactive(363902)
 
 
Unspecified(375)
 
 
BioAssay Types:
Screening(367135)
 
 
 
 
Confirmatory(899)
 
 
 
 
BioAssay Categories:
Biochemical(367605)
 
 
 
Cell-based(429)
 
 
 
 
BioActivity Types:
IC50(899)
 
 
 
 
Substance Types:
Chemical(368034)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 17    Data Row: 368034   Total Pages: 18402   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID162012461]
[CID24793614]
IC50 0.04413Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID686967, Type: confirmatory]
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2
[SID49734825]
[CID24793614]
IC50 0.04831Luminescence-based biochemical high throughput dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID651971, Type: confirmatory]
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3
[SID172125843]
[CID72720410]
IC50 0.05814Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round3) [AID1053132, Type: confirmatory]
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4
[SID162012461]
[CID24793614]
IC50 0.07509Late stage counterscreen for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS): Fluorescent Polarization-based biochemical dose response orthogonal assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID686969, Type: confirmatory]
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5
[SID164117574]
[CID2229551]
IC50 0.09949Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round2) [AID743300, Type: confirmatory]
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6
[SID49734825]
[CID24793614]
IC50 0.10055Counterscreen Fluorescent Polarization-based biochemical high throughput orthogonal dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID651989, Type: confirmatory]
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7
[SID164117574]
[CID2229551]
IC50 0.11036Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round001) [AID743153, Type: confirmatory]
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8
[SID164117574]
[CID2229551]
IC50 0.12782Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round3) [AID1053132, Type: confirmatory]
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9
[SID175606750]
[CID73438599]
IC50 0.13279Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round3) [AID1053132, Type: confirmatory]
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10
[SID172125843]
[CID72720410]
IC50 0.14504Late stage counterscreen for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS): Fluorescent Polarization-based biochemical dose response orthogonal assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS)(Round 3) [AID1053134, Type: confirmatory]
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11
[SID162012433]
[CID707837]
IC50 0.1475Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID686967, Type: confirmatory]
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12
[SID175606784]
[CID73438627]
IC50 0.16147Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round3) [AID1053132, Type: confirmatory]
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13
[SID17407303]
[CID11958558]
IC50 0.16292Counterscreen Fluorescent Polarization-based biochemical high throughput orthogonal dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID651989, Type: confirmatory]
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14
[SID164117574]
[CID2229551]
IC50 0.16711Late stage counterscreen for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS): Fluorescent Polarization-based biochemical dose response orthogonal assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS)(Round001) [AID743154, Type: confirmatory]
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15
[SID175606783]
[CID73438603]
IC50 0.16821Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round3) [AID1053132, Type: confirmatory]
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16
[SID17432769]
[CID707837]
IC50 0.17037Luminescence-based biochemical high throughput dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID651971, Type: confirmatory]
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17
[SID162012474]
[CID2973195]
IC50 0.17182Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) [AID686967, Type: confirmatory]
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18
[SID164117574]
[CID2229551]
IC50 0.18131Late stage counterscreen for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS): Fluorescent Polarization-based biochemical dose response orthogonal assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS)(Round2) [AID743299, Type: confirmatory]
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19
[SID175606743]
[CID73438629]
IC50 0.18787Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round3) [AID1053132, Type: confirmatory]
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20
[SID164117561]
[CID2869023]
IC50 0.19169Late stage luminescence-based biochemical dose response assay to identify inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) (Round001) [AID743153, Type: confirmatory]
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