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BioActivity Data for Gene USP8 (Gene ID:9101)

Also known as: HumORF8, SPG59, UBPY.
BioActivity Outcomes:
Inactive(16)
 
 
Unspecified(13)
 
 
BioAssay Types:
Literature(22)
 
 
 
Screening(4)
 
 
BioAssay Categories:
Biochemical(14)
 
 
 
Toxicity(3)
 
 
BioActivity Types:
IC50(5)
 
 
Substance Types:
Chemical(15)
 
 
 
RNAi(14)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 13    Data Row: 29   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103617247]
[CID10634145]
IC50 31.6Inhibition of core catalytic domain of USP8 (unknown origin) using ubiquitin-Rh110 as substrate [AID755341, Type: Literature] [gi:731046]
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2
[SID103769288]
[CID46174170]
IC50 100Inhibition of human USP8 using Ub-rhodamine 110 as substrate [AID1128606, Type: Literature] [gi:731046]
View
3
[SID242620571]
[CID86276129]
IC50 100Inhibition of human USP8 using Ub-rhodamine 110 as substrate [AID1128606, Type: Literature] [gi:731046]
View
4
[SID242620576]
[CID73659185]
IC50 100Inhibition of human USP8 using Ub-rhodamine 110 as substrate [AID1128606, Type: Literature] [gi:731046]
View
5
[SID242620577]
[CID73659186]
IC50 100Inhibition of human USP8 using Ub-rhodamine 110 as substrate [AID1128606, Type: Literature] [gi:731046]
View
6
[SID242633875]
[CID90675742]
Binding affinity to deubiquitinase USP08 (unknown origin) assessed as labeling after 4 hrs incubation [AID1143899, Type: Literature] [gi:731046]
View
7
[SID242633878]
[CID90675745]
Binding affinity to deubiquitinase USP08 (unknown origin) assessed as labeling after 4 hrs incubation [AID1143899, Type: Literature] [gi:731046]
View
8
[SID103769288]
[CID46174170]
Inhibition of human USP8 using Ub-rhodamine 110 as substrate at 31 uM [AID1128597, Type: Literature] [gi:731046]
View
9
[SID242620571]
[CID86276129]
Inhibition of human USP8 using Ub-rhodamine 110 as substrate at 31 uM [AID1128597, Type: Literature] [gi:731046]
View
10
[SID242620576]
[CID73659185]
Inhibition of human USP8 using Ub-rhodamine 110 as substrate at 31 uM [AID1128597, Type: Literature] [gi:731046]
View
11
[SID242620577]
[CID73659186]
Inhibition of human USP8 using Ub-rhodamine 110 as substrate at 31 uM [AID1128597, Type: Literature] [gi:731046]
View
12
[SID85108909]
siRNA Circadian Assay [AID1904, Type: other] [geneid:9101]
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13
[SID85101686]
siRNA Circadian Assay [AID1904, Type: other] [geneid:9101]
View
14
[SID160677610]
[CID11563133]
Inhibition of human USP8 using Ub-AMC as substrate at 1 to 30 uM after 60 mins by fluorometric analysis [AID761503, Type: Literature] [gi:731046]
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15
[SID160721475]
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity [AID1117281, Type: Literature] [geneid:9101]
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16
[SID160721476]
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity [AID1117281, Type: Literature] [geneid:9101]
View
17
[SID160721477]
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity [AID1117281, Type: Literature] [geneid:9101]
View
18
[SID144116952]
[CID60167849]
Inhibitors of USP1/UAF1: SAR in USP8 diubiquitin SDS-PAGE gel assay [AID651623, Type: other] [gi:116283245]
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19
[SID134310802]
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library) [AID651810, Type: Literature] [geneid:9101]
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20
[SID160721475]
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library) [AID651811, Type: Literature] [geneid:9101]
View