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USP5 (geneid:8078) - Gene BioActivity Data
Also known as: ISOT.
BioActivity Outcomes:
Active(11)
 
 
Inactive(11)
 
 
Unspecified(2)
 
 
BioAssay Types:
Literature(20)
 
 
 
Screening(1)
 
 
BioActivity Types:
IC50(2)
 
 
Ki(1)
 
 
Substance Types:
Chemical(16)
 
 
 
RNAi(8)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 17    Data Row: 24   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136938172]
[CID11222830]
IC50 3Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysis [AID761493, Type: Literature] [gi:1717869]
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2
[SID160677610]
[CID11563133]
IC50 5.9Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis [AID761509, Type: Literature] [gi:1717869]
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3
[SID160677610]
[CID11563133]
Ki 12.5Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate [AID761507, Type: Literature] [gi:1717869]
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4
[SID160677610]
[CID11563133]
Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using K48-linked tetraubiquitin as substrate assessed as substrate hydrolysis at 10 uM after 15 mins by SDS-PAGE analysis [AID761512, Type: Literature] [gi:1717869]
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5
[SID160677610]
[CID11563133]
Competitive binding affinity to human recombinant USP5 after 1 hr by SDS-PAGE analysis in presence of biotin-DMT [AID761516, Type: Literature] [gi:1717869]
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6
[SID160693760]
[CID70691637]
Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using K48-linked tetraubiquitin as substrate assessed as substrate hydrolysis at 5 to 50 uM after 15 mins by SDS-PAGE analysis [AID761510, Type: Literature] [gi:1717869]
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7
[SID160693760]
[CID70691637]
Binding affinity to human recombinant USP5 by SDS-PAGE analysis [AID761518, Type: Literature] [gi:1717869]
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8
[SID160666944]
[CID25191039]
Inhibition of human USP5 using Ub-AMC as substrate at 1 to 20 uM after 10 mins by fluorometric analysis [AID761500, Type: Literature] [gi:1717869]
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9
[SID160666944]
[CID25191039]
Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using K48-linked tetraubiquitin as substrate assessed as substrate hydrolysis at 20 uM after 15 mins by SDS-PAGE analysis [AID761511, Type: Literature] [gi:1717869]
View
10
[SID160666944]
[CID25191039]
Competitive binding affinity to human recombinant USP5 after 1 hr by SDS-PAGE analysis in presence of biotin-DMT [AID761516, Type: Literature] [gi:1717869]
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11
[SID160719608]
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library) [AID651811, Type: Literature] [geneid:8078]
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12
[SID85101787]
siRNA Circadian Assay [AID1904, Type: other] [geneid:8078]
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13
[SID85109010]
siRNA Circadian Assay [AID1904, Type: other] [geneid:8078]
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14
[SID103679414]
[CID45265923]
Inhibition of isopeptidase T at 40 uM [AID307543, Type: Literature] [gi:1717869]
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15
[SID134311515]
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes [AID624099, Type: Literature] [geneid:8078]
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16
[SID103261950]
[CID443118]
Inhibition of human USP5 using Ub4 as substrate at 50 uM after 10 mins by SDS-PAGE analysis [AID761495, Type: Literature] [gi:1717869]
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17
[SID103361782]
[CID10216098]
Inhibition of human USP5 using Ub4 as substrate at 50 uM after 10 mins by SDS-PAGE analysis [AID761495, Type: Literature] [gi:1717869]
View
18
[SID104242449]
[CID49864402]
Inhibition of human USP5 using Ub4 as substrate at 50 uM after 10 mins by SDS-PAGE analysis [AID761495, Type: Literature] [gi:1717869]
View
19
[SID144116952]
[CID60167849]
Inhibitors of USP1/UAF1: SAR in USP5 diubiquitin SDS-PAGE gel assay [AID651625, Type: other] [gi:13477329]
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20
[SID152153707]
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library) [AID651810, Type: Literature] [geneid:8078]
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