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VDR (geneid:7421) - Gene BioActivity Data
Also known as: NR1I1, PPP1R163.
BioActivity Outcomes:
Active(5938)
 
 
Inactive(420261)
 
 
Inconclusive(21893)
 
 
Unspecified(500)
 
 
BioAssay Types:
Confirmatory(428843)
 
 
 
 
Summary(18610)
 
 
 
 
Literature(1063)
 
 
 
 
 
Screening(47)
 
 
 
BioActivity Types:
Potency(438148)
 
 
 
 
IC50(296)
 
 
 
 
 
EC50(127)
 
 
 
 
 
Ki(12)
 
 
Substance Types:
Chemical(448580)
 
 
 
 
 
RNAi(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 182    Data Row: 448592   Total Pages: 22430   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103508828]
[CID44420575]
EC50 2e-06Induction of transactivation of human VDR responsive gene in COS7 cells by rat osteopontin luciferase reporter gene assay [AID280115, Type: Literature] [gi:137617]
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2
[SID103508814]
[CID44420574]
EC50 3e-06Induction of transactivation of human VDR responsive gene in COS7 cells by rat osteopontin luciferase reporter gene assay [AID280115, Type: Literature] [gi:137617]
View
3
[SID174512904]
[CID71764798]
EC50 1e-05Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay [AID760217, Type: Literature] [gi:137617]
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4
[SID103221863]
[CID5280453]
EC50 1e-05Activity at human VDR expressed in human HOS cells transfected with pGL3-hOc, pCDNA-hVDR and phRL-TK assessed as assessed as transcriptional activation measured 24 hrs post infection by luciferase reporter gene assay [AID622098, Type: Literature] [gi:137617]
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5
[SID103221863]
[CID5280453]
EC50 1.06e-05Effect on VDR transcriptional activity in human osteosarcoma cells [AID321740, Type: Literature] [gi:137617]
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6
[SID103221863]
[CID5280453]
EC50 2.6e-05Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay [AID760217, Type: Literature] [gi:137617]
View
7
[SID160701469]
[CID57522254]
IC50 2.9e-05Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after 16 hrs [AID673011, Type: Literature] [gi:137617]
View
8
[SID103702411]
[CID45484851]
ED50 3e-05Agonist activity at human VDR expressed in human HOS cells co-transfected with RXR gene assessed as osteocalcin promoter gene transactivation after 24 hrs by luciferase assay [AID447020, Type: Literature] [gi:137617]
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9
[SID103575226]
[CID24936209]
EC50 3.96e-05Effect on VDR transcriptional activity in human osteosarcoma cells [AID321740, Type: Literature] [gi:137617]
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10
[SID103575226]
[CID24936209]
EC50 4e-05Activity at human VDR expressed in human HOS cells transfected with pGL3-hOc, pCDNA-hVDR and phRL-TK assessed as assessed as transcriptional activation measured 24 hrs post infection by luciferase reporter gene assay [AID622098, Type: Literature] [gi:137617]
View
11
[SID174497335]
[CID71764801]
EC50 4.4e-05Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay [AID760217, Type: Literature] [gi:137617]
View
12
[SID134451656]
[CID56603803]
EC50 6e-05Activity at human VDR expressed in human HOS cells transfected with pGL3-hOc, pCDNA-hVDR and phRL-TK assessed as assessed as transcriptional activation measured 24 hrs post infection by luciferase reporter gene assay [AID622098, Type: Literature] [gi:137617]
View
13
[SID103517327]
[CID44423319]
EC50 7e-05Inhibition of human VDR induced-transcriptional transactivation of luciferase reporter gene in COS7 cells after 24 hrs [AID287170, Type: Literature] [gi:137617]
View
14
[SID174524899]
[CID73357083]
EC50 0.0001Agonist activity at VDR ligand binding domain (unknown origin) by reporter gene assay [AID775185, Type: Literature] [gi:137617]
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15
[SID103702429]
[CID44555479]
ED50 0.00012Agonist activity at human VDR expressed in human HOS cells co-transfected with RXR gene assessed as osteocalcin promoter gene transactivation after 24 hrs by luciferase assay [AID447020, Type: Literature] [gi:137617]
View
16
[SID174492258]
[CID71764800]
EC50 0.00015Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay [AID760217, Type: Literature] [gi:137617]
View
17
[SID103508829]
[CID44420576]
EC50 0.0002Induction of transactivation of human VDR responsive gene in COS7 cells by rat osteopontin luciferase reporter gene assay [AID280115, Type: Literature] [gi:137617]
View
18
[SID174523160]
[CID71765011]
EC50 0.00021Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay [AID760217, Type: Literature] [gi:137617]
View
19
[SID174517929]
[CID71764799]
EC50 0.00029Transactivation of VDR-mediated osteocalcin promoter in human HOS/SF cells after 24 hrs by luciferase reporter gene assay [AID760217, Type: Literature] [gi:137617]
View
20
[SID160674578]
[CID57522255]
IC50 0.00038Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after 16 hrs [AID673011, Type: Literature] [gi:137617]
View