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TP53 (geneid:7157) - Gene BioActivity Data
Also known as: BCC7, LFS1, P53, TRP53.
BioActivity Outcomes:
Active(6151)
 
 
Inactive(679517)
 
 
Inconclusive(38596)
 
 
Unspecified(520)
 
 
BioAssay Types:
Confirmatory(696802)
 
 
 
 
 
Screening(16964)
 
 
 
Summary(10488)
 
 
 
 
Literature(528)
 
 
 
 
BioActivity Types:
Potency(707290)
 
 
 
 
 
IC50(342)
 
 
 
Ki(58)
 
 
 
 
Kd(4)
 
 
EC50(2)
 
 
Substance Types:
Chemical(724769)
 
 
 
 
 
RNAi(15)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 126    Data Row: 724784   Total Pages: 36240   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID163331640]
[CID67998380]
IC50 0.0009Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View
2
[SID160701617]
[CID56965957]
IC50 0.0011Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View
3
[SID163317819]
[CID58573876]
IC50 0.0017Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View
4
[SID163314357]
[CID60154126]
IC50 0.0018Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View
5
[SID144207181]
[CID43116]
Potency-Replicate_1 0.0021qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory] [gi:269849759]
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6
[SID160690851]
[CID56591154]
IC50 0.0022Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View
7
[SID144209680]
[CID457193]
Ratio Potency (uM) 0.00227757qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary] [gi:269849759]
View
8
[SID144209680]
[CID457193]
Potency-Replicate_1 0.0027qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory] [gi:269849759]
View
9
[SID144206639]
[CID148124]
Potency-Replicate_1 0.0027qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory] [gi:269849759]
View
10
[SID163335100]
[CID56591137]
IC50 0.0028Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View
11
[SID160701617]
[CID56965957]
IC50 0.0042Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay in presence of 15% human serum [AID706602, Type: Literature] [gi:269849759]
View
12
[SID163317818]
[CID56591324]
IC50 0.0042Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View
13
[SID144206334]
[CID148124]
Potency-Replicate_1 0.0042qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory] [gi:269849759]
View
14
[SID103441496]
[CID11250180]
Kd 0.0048Binding affinity against p53-binding site of Benzodiazepinedione HDM2 [AID238133, Type: Literature] [gi:269849759]
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15
[SID144205550]
[CID457193]
Potency-Replicate_1 0.0053qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory] [gi:269849759]
View
16
[SID144206334]
[CID148124]
Ratio Potency (uM) 0.00530804qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary] [gi:269849759]
View
17
[SID144206639]
[CID148124]
Ratio Potency (uM) 0.00562256qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary] [gi:269849759]
View
18
[SID144205550]
[CID457193]
Ratio Potency (uM) 0.00630862qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary] [gi:269849759]
View
19
[SID163317819]
[CID58573876]
IC50 0.0068Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay in presence of 15% human serum [AID706602, Type: Literature] [gi:269849759]
View
20
[SID163314356]
[CID56591304]
IC50 0.0076Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:269849759]
View