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TNF (geneid:7124) - Gene BioActivity Data
Also known as: DADB-70P7.1, DIF, TNF-alpha, TNFA, TNFSF2.
BioActivity Outcomes:
Active(1809)
 
 
Inactive(2856)
 
 
Inconclusive(183)
 
 
Unspecified(5)
 
 
BioAssay Types:
Confirmatory(2329)
 
 
 
 
Literature(30)
 
 
 
 
Screening(5)
 
 
BioActivity Types:
Potency(1408)
 
 
 
 
IC50(916)
 
 
 
Kd(11)
 
 
Substance Types:
Chemical(4841)
 
 
 
 
 
RNAi(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 30    Data Row: 4853   Total Pages: 243   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103452885]
[CID44395506]
IC50 0.0104Inhibitory concentration against TNF-alpha release in LPS treated whole blood [AID247750, Type: Literature] [gi:135934]
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2
[SID85248280]
[CID44229055]
IC50_Mean 0.0244SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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3
[SID85176833]
[CID6861088]
IC50_Mean 0.0369SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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4
[SID85176834]
[CID7584226]
IC50_Mean 0.0373SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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5
[SID85176823]
[CID2401486]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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6
[SID85176824]
[CID2409986]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
7
[SID85176828]
[CID3390551]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
8
[SID85176832]
[CID16460826]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
9
[SID85176822]
[CID5057111]
IC50_Mean 0.0456SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
10
[SID103272899]
[CID9886977]
IC50 0.048Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature] [gi:135934]
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11
[SID85176814]
[CID9587731]
IC50_Mean 0.0706SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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12
[SID85176812]
[CID24817336]
IC50_Mean 0.0793SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
13
[SID85248281]
[CID1106361]
IC50_Mean 0.14SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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14
[SID85176810]
[CID24792090]
IC50_Mean 0.179SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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15
[SID85176813]
[CID24793159]
IC50_Mean 0.2SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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16
[SID85176607]
[CID2196728]
IC50_Mean 0.206SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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17
[SID85176798]
[CID7110073]
IC50_Mean 0.23SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
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18
[SID85176785]
[CID44182145]
IC50_Mean 0.236SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
19
[SID85176805]
[CID709072]
IC50_Mean 0.246SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
20
[SID103273474]
[CID9907830]
IC50 0.269Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature] [gi:135934]
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