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TNF (geneid:7124) - Gene BioActivity Data
Also known as: DADB-70P7.1, DIF, TNF-alpha, TNFA, TNFSF2.
BioActivity Outcomes:
Active(1809)
 
 
Inactive(2851)
 
 
Inconclusive(183)
 
 
Unspecified(5)
 
 
BioAssay Types:
Confirmatory(2318)
 
 
 
 
Literature(31)
 
 
 
 
BioActivity Types:
Potency(1408)
 
 
 
 
IC50(916)
 
 
 
Kd(11)
 
 
Substance Types:
Chemical(4841)
 
 
 
 
 
RNAi(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 28    Data Row: 4848   Total Pages: 97   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103452885]
[CID44395506]
IC50 0.0104Inhibitory concentration against TNF-alpha releasein LPS treated whole blood [AID247750, Type: Literature] [gi:135934]
View
2
[SID85248280]
[CID44229055]
IC50_Mean 0.0244SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
3
[SID85176833]
[CID6861088]
IC50_Mean 0.0369SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
4
[SID85176834]
[CID7584226]
IC50_Mean 0.0373SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
5
[SID85176823]
[CID2401486]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
6
[SID85176824]
[CID2409986]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
7
[SID85176828]
[CID3390551]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
8
[SID85176832]
[CID16460826]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
9
[SID85176822]
[CID5057111]
IC50_Mean 0.0456SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
10
[SID103272899]
[CID9886977]
IC50 0.048Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature] [gi:135934]
View
11
[SID85176814]
[CID9587731]
IC50_Mean 0.0706SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
12
[SID85176812]
[CID24817336]
IC50_Mean 0.0793SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
13
[SID85248281]
[CID1106361]
IC50_Mean 0.14SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
14
[SID85176810]
[CID24792090]
IC50_Mean 0.179SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
15
[SID85176813]
[CID24793159]
IC50_Mean 0.2SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
16
[SID85176607]
[CID2196728]
IC50_Mean 0.206SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
17
[SID85176798]
[CID7110073]
IC50_Mean 0.23SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
18
[SID85176785]
[CID44182145]
IC50_Mean 0.236SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
19
[SID85176805]
[CID709072]
IC50_Mean 0.246SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
20
[SID103273474]
[CID9907830]
IC50 0.269Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature] [gi:135934]
View
21
[SID49728459]
[CID9566902]
IC50 0.3125HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
22
[SID3716460]
[CID2524461]
IC50 0.3125HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
23
[SID17386369]
[CID1014820]
IC50 0.3125HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
24
[SID24832798]
[CID5057111]
IC50 0.3125HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
25
[SID26671426]
[CID16410414]
IC50 0.3125HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
26
[SID47200829]
[CID1106361]
IC50 0.3125HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
27
[SID26660424]
[CID1967479]
IC50 0.34475HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
28
[SID85176795]
[CID44182149]
IC50_Mean 0.372SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
29
[SID17389540]
[CID2724385]
Potency 0.3758qHTS assay to identify small molecules that stimulate Tumor Necrosis Factor-alpha (TNF-alpha) secretion [AID651757, Type: confirmatory] [gi:25952111]
View
30
[SID85176821]
[CID6297486]
IC50_Mean 0.414SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
31
[SID49666789]
[CID786617]
IC50 0.451HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
32
[SID85176803]
[CID12006093]
IC50_Mean 0.462SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
33
[SID26664329]
[CID233874]
IC50 0.47775HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
34
[SID85248285]
[CID1106353]
IC50_Mean 0.491SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
35
[SID85176783]
[CID44182143]
IC50_Mean 0.584SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
36
[SID85176595]
[CID2279440]
IC50_Mean 0.616SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
37
[SID85176608]
[CID1288978]
IC50_Mean 0.627SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
38
[SID85176609]
[CID2211281]
IC50_Mean 0.639SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
39
[SID85248289]
[CID1360138]
IC50_Mean 0.65SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
40
[SID22402176]
[CID7110073]
IC50 0.66625HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
41
[SID14740639]
[CID2263502]
IC50 0.70275HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
42
[SID85176626]
[CID24791863]
IC50_Mean 0.703SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
43
[SID85176826]
[CID2524412]
IC50_Mean 0.704SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
44
[SID85176811]
[CID24793944]
IC50_Mean 0.712SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
45
[SID17410873]
[CID2763795]
IC50 0.7485HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
46
[SID85176825]
[CID5214280]
IC50_Mean 0.752SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
47
[SID85176829]
[CID16954]
IC50_Mean 0.762SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
48
[SID7970738]
[CID866501]
IC50 0.78325HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
49
[SID24823151]
[CID15996839]
IC50 0.84175HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction [AID2485, Type: confirmatory] [gi:25952111]
View
50
[SID85176591]
[CID830837]
IC50_Mean 0.87SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View