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BioActivity Data for Gene TNF (Gene ID:7124)

Also known as: DIF, TNF-alpha, TNFA, TNFSF2.
BioActivity Outcomes:
Active(1821)
 
 
Inactive(2859)
 
 
Inconclusive(183)
 
 
Unspecified(5)
 
 
BioAssay Types:
Confirmatory(2318)
 
 
 
 
Literature(58)
 
 
 
 
Screening(5)
 
 
BioAssay Categories:
Biochemical(43)
 
 
 
 
Cell-based(18)
 
 
 
 
Toxicity(3)
 
 
BioActivity Types:
Potency(1408)
 
 
 
 
IC50(916)
 
 
 
Kd(23)
 
 
Substance Types:
Chemical(4853)
 
 
 
 
 
RNAi(15)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 32    Data Row: 4868   Total Pages: 244   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136923167]
[CID20055989]
Kd 0.00245Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
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2
[SID103599915]
[CID23247895]
Kd 0.00269Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
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3
[SID103562257]
[CID5327044]
Kd 0.00381Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
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4
[SID136932883]
[CID57396771]
Kd 0.00839Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
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5
[SID103728848]
[CID471002]
Kd 0.00853Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
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6
[SID103740635]
[CID10098048]
Kd 0.00881Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
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7
[SID103452885]
[CID44395506]
IC50 0.0104Inhibitory concentration against TNF-alpha release in LPS treated whole blood [AID247750, Type: Literature] [gi:135934]
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8
[SID242648413]
[CID90645096]
Kd 0.0129Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
View
9
[SID136930782]
[CID471008]
Kd 0.0168Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
View
10
[SID163322113]
[CID14109406]
Kd 0.0186Binding affinity to TNF-alpha (unknown origin) [AID1156798, Type: Literature] [gi:135934]
View
11
[SID85248280]
[CID44229055]
IC50_Mean 0.0244SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
12
[SID85176833]
[CID6861088]
IC50_Mean 0.0369SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
13
[SID85176834]
[CID7584226]
IC50_Mean 0.0373SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
14
[SID85176823]
[CID2401486]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
15
[SID85176824]
[CID2409986]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
16
[SID85176828]
[CID3390551]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
17
[SID85176832]
[CID16460826]
IC50_Mean 0.0391SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
18
[SID85176822]
[CID5057111]
IC50_Mean 0.0456SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View
19
[SID103272899]
[CID9886977]
IC50 0.048Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCs [AID210150, Type: Literature] [gi:135934]
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20
[SID85176814]
[CID9587731]
IC50_Mean 0.0706SAR analysis of inhibitors of TNFa specific NF-kB induction revised [AID2337, Type: confirmatory] [gi:25952111]
View