Bookmark and Share
ADAM17 (geneid:6868) - Gene BioActivity Data
Also known as: ADAM18, CD156B, CSVP, NISBD, TACE.
BioActivity Outcomes:
Active(5618)
 
 
Inactive(370810)
 
 
Inconclusive(13)
 
 
Unspecified(247)
 
 
BioAssay Types:
Screening(375273)
 
 
 
Literature(932)
 
 
 
 
 
Confirmatory(483)
 
 
 
BioActivity Types:
IC50(1137)
 
 
 
 
 
Ki(126)
 
 
 
Substance Types:
Chemical(376681)
 
 
 
 
 
RNAi(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 93    Data Row: 376688   Total Pages: 7534   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124964061]
[CID53320639]
IC50 0.0001Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
2
[SID103606786]
[CID25138228]
Ki 0.00014Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
3
[SID103628924]
[CID44581139]
Ki 0.00014Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
4
[SID103629010]
[CID44581163]
Ki 0.00015Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
5
[SID103629012]
[CID44581165]
Ki 0.00015Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
6
[SID103606787]
[CID24978491]
Ki 0.00018Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
7
[SID103629013]
[CID44581166]
Ki 0.00021Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
8
[SID103627927]
[CID44580803]
Ki 0.00025Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
9
[SID124974652]
[CID15986873]
IC50 0.00027Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
10
[SID124976389]
[CID15986261]
IC50 0.00028Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
11
[SID103627924]
[CID44580800]
Ki 0.00028Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
12
[SID103627926]
[CID44580802]
Ki 0.0003Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
13
[SID124973674]
[CID15986115]
IC50 0.0003Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
14
[SID103627925]
[CID44580801]
Ki 0.00036Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
15
[SID103627928]
[CID44580804]
Ki 0.00038Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
16
[SID103185380]
[CID119031]
Ki 0.0004Inhibition of recombinant human TNF-alpha converting enzyme (TACE) [AID210018, Type: Literature] [gi:14423632]
View
17
[SID103185380]
[CID119031]
Ki 0.0004Inhibition of recombinant human tumor necrosis factor-alpha converting enzyme [AID215597, Type: Literature] [gi:14423632]
View
18
[SID124964058]
[CID53320636]
IC50 0.00046Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
19
[SID103453536]
[CID44395935]
IC50 0.00048Inhibitory concentration against TNF-alpha release in LPS treated whole blood [AID241017, Type: Literature] [gi:14423632]
View
20
[SID103559487]
[CID15986113]
IC50 0.0005Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
21
[SID124958831]
[CID15986257]
IC50 0.00053Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
22
[SID103217475]
[CID11246575]
Ki 0.00053Inhibition of recombinant human TNF-alpha converting enzyme [AID210019, Type: Literature] [gi:14423632]
View
23
[SID103217475]
[CID11246575]
Ki 0.00053Inhibition of human tumor necrosis factor alpha converting enzyme [AID215262, Type: Literature] [gi:14423632]
View
24
[SID103627929]
[CID44580805]
Ki 0.00054Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
25
[SID103217455]
[CID10388523]
Ki 0.00057Inhibition of recombinant human TNF-alpha converting enzyme [AID210019, Type: Literature] [gi:14423632]
View
26
[SID103272899]
[CID9886977]
Ki 0.0006Inhibitory potency against Tumor necrosis factor alpha converting enzyme (TACE) [AID215264, Type: Literature] [gi:14423632]
View
27
[SID103272899]
[CID9886977]
Ki 0.0006Binding affinity to recombinant TACE [AID264666, Type: Literature] [gi:14423632]
View
28
[SID103627930]
[CID44580806]
Ki 0.00063Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
29
[SID124956211]
[CID15986256]
IC50 0.00066Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
30
[SID103746303]
[CID45378253]
IC50 0.0007Inhibition of human recombinant ADAM17 by fluorometric assay [AID473233, Type: Literature] [gi:14423632]
View
31
[SID103629011]
[CID44581164]
Ki 0.00076Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
32
[SID103217476]
[CID44286663]
Ki 0.00084Inhibition of recombinant human TNF-alpha converting enzyme [AID210019, Type: Literature] [gi:14423632]
View
33
[SID124956212]
[CID53316692]
IC50 0.0009Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
34
[SID103494227]
[CID23513825]
IC50 0.001Inhibition of TACE by FRET assay [AID268588, Type: Literature] [gi:14423632]
View
35
[SID103494227]
[CID23513825]
IC50 0.001Inhibition of human TACE catalytic domain expressed in CHO cells by FRET assay [AID375765, Type: Literature] [gi:14423632]
View
36
[SID103494239]
[CID44143475]
IC50 0.001Inhibition of human TACE catalytic domain expressed in CHO cells by FRET assay [AID375765, Type: Literature] [gi:14423632]
View
37
[SID103494254]
[CID44413992]
IC50 0.001Inhibition of TACE by FRET assay [AID268588, Type: Literature] [gi:14423632]
View
38
[SID103494246]
[CID23513795]
IC50 0.001Inhibition of TACE by FRET assay [AID268588, Type: Literature] [gi:14423632]
View
39
[SID103494272]
[CID44414001]
IC50 0.001Inhibition of TACE by FRET assay [AID268588, Type: Literature] [gi:14423632]
View
40
[SID103540565]
[CID24860425]
IC50 0.001Inhibition of human TACE expressed in CHO cells by FRET assay [AID300532, Type: Literature] [gi:14423632]
View
41
[SID103628923]
[CID44581138]
Ki 0.001Inhibition of human recombinant TACE [AID348867, Type: Literature] [gi:14423632]
View
42
[SID103634776]
[CID11698938]
IC50 0.001Inhibition of human TACE catalytic domain expressed in CHO cells by FRET assay [AID375765, Type: Literature] [gi:14423632]
View
43
[SID103634857]
[CID44143478]
IC50 0.001Inhibition of human TACE catalytic domain expressed in CHO cells by FRET assay [AID375765, Type: Literature] [gi:14423632]
View
44
[SID103634936]
[CID44143481]
IC50 0.001Inhibition of human TACE catalytic domain expressed in CHO cells by FRET assay [AID375765, Type: Literature] [gi:14423632]
View
45
[SID103578315]
[CID24799781]
Ki 0.001Inhibition of human recombinant TACE [AID316583, Type: Literature] [gi:14423632]
View
46
[SID124964062]
[CID15986607]
IC50 0.00104Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
47
[SID124958833]
[CID15986703]
IC50 0.00107Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
48
[SID124972058]
[CID15986869]
IC50 0.00107Inhibition of human TACE by fluorescent spectroscopy [AID548722, Type: Literature] [gi:14423632]
View
49
[SID103635120]
[CID44143487]
IC50 0.0012Inhibition of human TACE catalytic domain expressed in CHO cells by FRET assay [AID375765, Type: Literature] [gi:14423632]
View
50
[SID103494273]
[CID44414002]
IC50 0.0014Inhibition of TACE by FRET assay [AID268588, Type: Literature] [gi:14423632]
View