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PTGS2 (geneid:5743) - Gene BioActivity Data
Also known as: COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2.
BioActivity Outcomes:
Active(1323)
 
 
Inactive(120)
 
 
Inconclusive(101)
 
 
Unspecified(2261)
 
 
BioAssay Types:
Literature(2809)
 
 
 
 
 
BioActivity Types:
IC50(2454)
 
 
 
 
 
Ki(4)
 
 
 
EC50(1)
 
 
Substance Types:
Chemical(3798)
 
 
 
 
 
RNAi(7)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 320    Data Row: 3805   Total Pages: 77   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136940759]
[CID56924662]
IC50 0.0002Inhibition of human recombinant COX2 [AID648862, Type: Literature] [gi:3915797]
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2
[SID103687210]
[CID9931215]
IC50 0.00025Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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3
[SID103690694]
[CID10180742]
IC50 0.00028Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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4
[SID103576401]
[CID24882361]
IC50 0.0003Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
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5
[SID103576701]
[CID44456883]
IC50 0.0004Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
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6
[SID103452140]
[CID11395292]
IC50 0.00044Inhibition of human cyclooxygenase-2 expressed in COS cells [AID241308, Type: Literature] [gi:3915797]
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7
[SID103682006]
[CID9930803]
IC50 0.0005Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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8
[SID103297833]
[CID9851770]
IC50 0.0011Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: other] [gi:3915797]
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9
[SID103299365]
[CID9817667]
IC50 0.0012Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: other] [gi:3915797]
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10
[SID103576617]
[CID44456839]
IC50 0.0012Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
View
11
[SID103576569]
[CID44456825]
IC50 0.0012Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
View
12
[SID103687227]
[CID45270348]
IC50 0.0013Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
View
13
[SID103687228]
[CID45270349]
IC50 0.0014Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
View
14
[SID103497297]
[CID16007065]
IC50 0.0018Inhibition of COX2 [AID270014, Type: Literature] [gi:3915797]
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15
[SID103497298]
[CID16007066]
IC50 0.0019Inhibition of COX2 [AID270014, Type: Literature] [gi:3915797]
View
16
[SID103471304]
[CID44404327]
IC50 0.002Inhibitory activity against human recombinant cyclooxygenase 2 [AID254750, Type: Literature] [gi:3915797]
View
17
[SID103450939]
[CID44394196]
IC50 0.002Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
18
[SID103450980]
[CID44394229]
IC50 0.002Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
19
[SID103452362]
[CID11725371]
IC50 0.002Inhibition of human cyclooxygenase-2 expressed in COS cells [AID241308, Type: Literature] [gi:3915797]
View
20
[SID103223949]
[CID3177]
IC50 0.002Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassay [AID432572, Type: Literature] [gi:3915797]
View
21
[SID103683704]
[CID45268661]
IC50 0.002Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
View
22
[SID103576520]
[CID24205505]
IC50 0.0021Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
View
23
[SID103223949]
[CID3177]
IC50 0.0021Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: other] [gi:3915797]
View
24
[SID103181002]
[CID2662]
IC50 0.0022Inhibition of COX2 [AID270014, Type: Literature] [gi:3915797]
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25
[SID103299681]
[CID18969715]
IC50 0.0022Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: other] [gi:3915797]
View
26
[SID103576355]
[CID44456711]
IC50 0.0024Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
View
27
[SID103685415]
[CID45269513]
IC50 0.0024Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
View
28
[SID103299685]
[CID9883822]
IC50 0.0028Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: other] [gi:3915797]
View
29
[SID103452401]
[CID9832687]
IC50 0.003Inhibition of human cyclooxygenase-2 expressed in COS cells [AID241308, Type: Literature] [gi:3915797]
View
30
[SID103685291]
[CID45269433]
IC50 0.003Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
View
31
[SID123094129]
[CID10064144]
IC50 0.003Inhibition of human COX-2 [AID539220, Type: Literature] [gi:3915797]
View
32
[SID103450788]
[CID44394101]
IC50 0.00302Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
33
[SID103450833]
[CID44394134]
IC50 0.00302Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
34
[SID103450740]
[CID44394065]
IC50 0.00398Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
35
[SID103450697]
[CID44394041]
IC50 0.00398Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
36
[SID103451022]
[CID44394264]
IC50 0.00398Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
37
[SID103576703]
[CID44456885]
IC50 0.0041Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
View
38
[SID103293849]
[CID60726]
IC50 0.0048DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) [AID625244, Type: other] [gi:3915797]
View
39
[SID103681879]
[CID45267710]
IC50 0.005Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
View
40
[SID103694284]
[CID45273829]
IC50 0.005Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
View
41
[SID103299653]
[CID18969710]
IC50 0.005Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: other] [gi:3915797]
View
42
[SID103225393]
[CID119607]
IC50 0.005Inhibitory activity against human recombinant cyclooxygenase 2 [AID254750, Type: Literature] [gi:3915797]
View
43
[SID103191369]
[CID3033]
IC50 0.005Inhibitory concentration against COX-2 upon incubation for 15 minutes at 37 degree C [AID254882, Type: Literature] [gi:3915797]
View
44
[SID124956101]
[CID53316646]
IC50 0.005Inhibition of human COX2 [AID547806, Type: Literature] [gi:3915797]
View
45
[SID124969290]
[CID9905741]
IC50 0.005Inhibition of human COX2 [AID547806, Type: Literature] [gi:3915797]
View
46
[SID103450984]
[CID44394233]
IC50 0.00501Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
47
[SID103450951]
[CID44394205]
IC50 0.00501Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
48
[SID103450864]
[CID44394151]
IC50 0.00501Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
View
49
[SID103575957]
[CID44456510]
IC50 0.0051Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
View
50
[SID103576053]
[CID44456567]
IC50 0.0054Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
View