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PTGS2 (geneid:5743) - Gene BioActivity Data
Also known as: COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2.
BioActivity Outcomes:
Active(1467)
 
 
Inactive(130)
 
 
Inconclusive(101)
 
 
Unspecified(2401)
 
 
BioAssay Types:
Literature(2992)
 
 
 
 
 
Confirmatory(1012)
 
 
 
Screening(4)
 
 
BioActivity Types:
IC50(2614)
 
 
 
 
 
Ki(9)
 
 
 
Kd(3)
 
 
EC50(1)
 
 
Substance Types:
Chemical(4088)
 
 
 
 
 
RNAi(11)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 367    Data Row: 4099   Total Pages: 205   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136940759]
[CID56924662]
IC50 0.0002Inhibition of human recombinant COX2 [AID648862, Type: Literature] [gi:3915797]
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2
[SID103687210]
[CID9931215]
IC50 0.00025Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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3
[SID103690694]
[CID10180742]
IC50 0.00028Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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4
[SID103576401]
[CID24882361]
IC50 0.0003Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
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5
[SID103576701]
[CID44456883]
IC50 0.0004Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
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6
[SID103452140]
[CID11395292]
IC50 0.00044Inhibition of human cyclooxygenase-2 expressed in COS cells [AID241308, Type: Literature] [gi:3915797]
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7
[SID103682006]
[CID9930803]
IC50 0.0005Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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8
[SID103297833]
[CID9851770]
IC50 0.0011Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: confirmatory] [gi:3915797]
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9
[SID103299365]
[CID9817667]
IC50 0.0012Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2 [AID162474, Type: confirmatory] [gi:3915797]
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10
[SID103576617]
[CID44456839]
IC50 0.0012Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
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11
[SID103576569]
[CID44456825]
IC50 0.0012Inhibition of human COX2 in human whole blood [AID319991, Type: Literature] [gi:3915797]
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12
[SID103687227]
[CID45270348]
IC50 0.0013Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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13
[SID103687228]
[CID45270349]
IC50 0.0014Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 hr before arachidonic acid challenge by enzyme immunoassay [AID432545, Type: Literature] [gi:3915797]
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14
[SID103497297]
[CID16007065]
IC50 0.0018Inhibition of COX2 [AID270014, Type: Literature] [gi:3915797]
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15
[SID103497298]
[CID16007066]
IC50 0.0019Inhibition of COX2 [AID270014, Type: Literature] [gi:3915797]
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16
[SID103471304]
[CID44404327]
IC50 0.002Inhibitory activity against human recombinant cyclooxygenase 2 [AID254750, Type: Literature] [gi:3915797]
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17
[SID103450939]
[CID44394196]
IC50 0.002Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
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18
[SID103450980]
[CID44394229]
IC50 0.002Binding affinity for Prostaglandin G/H synthase 2 (COX-2) [AID241424, Type: Literature] [gi:3915797]
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19
[SID103452362]
[CID11725371]
IC50 0.002Inhibition of human cyclooxygenase-2 expressed in COS cells [AID241308, Type: Literature] [gi:3915797]
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20
[SID103223949]
[CID3177]
IC50 0.002Inhibition of human COX2 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassay [AID432572, Type: Literature] [gi:3915797]
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