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PPARA (geneid:5465) - Gene BioActivity Data
Also known as: SC22CB-5E3.5, NR1C1, PPAR, PPARalpha, hPPAR.
BioActivity Outcomes:
Active(2427)
 
 
Inactive(3088)
 
 
Inconclusive(201)
 
 
Unspecified(1730)
 
 
BioAssay Types:
Literature(4389)
 
 
 
 
 
Confirmatory(3031)
 
 
 
 
 
Screening(18)
 
 
 
BioActivity Types:
Potency(2864)
 
 
 
 
EC50(2330)
 
 
 
 
 
IC50(781)
 
 
 
 
 
Ki(60)
 
 
 
 
 
Kd(17)
 
 
 
Substance Types:
Chemical(7434)
 
 
 
 
 
RNAi(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 424    Data Row: 7446   Total Pages: 373   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103283308]
[CID10004270]
EC50 2e-11Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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2
[SID103282873]
[CID9890585]
EC50 4e-11Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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3
[SID103422205]
[CID11049998]
EC50 9.77e-09Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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4
[SID134436215]
[CID56659348]
EC50 5e-08Transactivation of human PPARalpha expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610309, Type: Literature] [gi:3041727]
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5
[SID134459372]
[CID56679849]
EC50 6e-08Transactivation of human PPARalpha expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610309, Type: Literature] [gi:3041727]
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6
[SID103295006]
[CID446758]
EC50 6.17e-08Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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7
[SID134447814]
[CID56669690]
EC50 7e-08Transactivation of human PPARalpha expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610309, Type: Literature] [gi:3041727]
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8
[SID103295111]
[CID44321572]
EC50 2.69e-07Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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9
[SID134455510]
[CID53233135]
EC50 3.1e-07Transactivation of human PPARalpha expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610309, Type: Literature] [gi:3041727]
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10
[SID103294065]
[CID44320978]
EC50 5.37e-07Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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11
[SID103422072]
[CID10896153]
EC50 7.94e-07Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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12
[SID103295062]
[CID44321548]
EC50 1.2e-06Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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13
[SID103293909]
[CID44320897]
EC50 1.66e-06Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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14
[SID103194827]
[CID447458]
EC50 1.82e-06Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
View
15
[SID103295113]
[CID44321573]
EC50 2.19e-06Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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16
[SID103610257]
[CID44571517]
EC50 3.8e-06Agonist activity at human PPARalpha transactivation expressed in human HePG2 cells [AID371249, Type: Literature] [gi:3041727]
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17
[SID103294918]
[CID44321463]
EC50 4.9e-06Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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18
[SID103294875]
[CID44321441]
EC50 9.55e-06Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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19
[SID103294438]
[CID44321201]
EC50 1.29e-05Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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20
[SID103295005]
[CID44321517]
EC50 1.48e-05Transactivation of GAL4-fused Homo sapiens (human) PPARalpha/PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter gene assay [AID1105617, Type: confirmatory] [gi:3041727]
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