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OPRK1 (geneid:4986) - Gene BioActivity Data
Also known as: K-OR-1, KOR, KOR-1, OPRK.
BioActivity Outcomes:
Probe(4)
 
 
Active(3649)
 
 
Inactive(591068)
 
 
Inconclusive(276)
 
 
Unspecified(2456)
 
 
BioAssay Types:
Confirmatory(575578)
 
 
 
Screening(16001)
 
 
 
Literature(4882)
 
 
 
 
 
Summary(4)
 
 
BioActivity Types:
IC50(292290)
 
 
 
 
 
EC50(285207)
 
 
 
 
 
Ki(2036)
 
 
 
 
 
Substance Types:
Chemical(597446)
 
 
 
 
 
 
RNAi(7)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 532    Data Row: 597453   Total Pages: 11950   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87218782]
[CID5236771]
Summary of small molecule agonists of the kappa opioid receptor [AID1786, Type: summary] [gi:39725940]
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2
[SID87218794]
[CID3342390]
Summary of small molecule antagonists of the kappa opioid receptor [AID1785, Type: summary] [gi:39725940]
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3
[SID87334039]
[CID44601470]
Summary of small molecule agonists of the kappa opioid receptor [AID1786, Type: summary] [gi:39725940]
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4
[SID88442997]
[CID44665680]
Summary of small molecule antagonists of the kappa opioid receptor [AID1785, Type: summary] [gi:39725940]
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5
[SID103500899]
[CID16087270]
IC50 3e-06Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding [AID273145, Type: Literature] [gi:116242691]
View
6
[SID134434099]
[CID6602241]
Ki 3e-06Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells [AID259396, Type: Literature] [gi:116242691]
View
7
[SID103500785]
[CID16087283]
IC50 6e-06Activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding [AID273145, Type: Literature] [gi:116242691]
View
8
[SID164132787]
[CID71625152]
EC50 6.1e-06Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
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9
[SID164132788]
[CID71625277]
EC50 7e-06Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
10
[SID164144042]
[CID71625278]
EC50 7.7e-06Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
11
[SID164129948]
[CID71625279]
EC50 9.8e-06Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
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12
[SID164135610]
[CID71624552]
EC50 1.1e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
13
[SID164149695]
[CID71625151]
EC50 1.3e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
14
[SID164146758]
[CID71625027]
Ki 1.5e-05Displacement of [3H]-diprenorphine from human KOR expressed in CHO cells [AID735689, Type: Literature] [gi:116242691]
View
15
[SID164135611]
[CID71624663]
EC50 1.6e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
16
[SID164138476]
[CID71624555]
EC50 1.7e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
17
[SID164149694]
[CID71625028]
Ki 1.9e-05Displacement of [3H]-diprenorphine from human KOR expressed in CHO cells [AID735689, Type: Literature] [gi:116242691]
View
18
[SID164138472]
[CID71625029]
Ki 2e-05Displacement of [3H]-diprenorphine from human KOR expressed in CHO cells [AID735689, Type: Literature] [gi:116242691]
View
19
[SID164138473]
[CID71625393]
EC50 2e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
20
[SID103328513]
[CID44337683]
Ki 2e-05Ratio of kappa/delta-opioid receptors Binding affinity [AID228131, Type: Literature] [gi:116242691]
View
21
[SID164129947]
[CID71625149]
Ki 2.5e-05Displacement of [3H]-diprenorphine from human KOR expressed in CHO cells [AID735689, Type: Literature] [gi:116242691]
View
22
[SID103575487]
[CID6445230]
EC50 2.5e-05Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID321653, Type: Literature] [gi:116242691]
View
23
[SID103698780]
[CID5480230]
Ki 2.7e-05Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cells [AID410720, Type: Literature] [gi:116242691]
View
24
[SID164129951]
[CID71624553]
EC50 2.7e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
25
[SID164149696]
[CID71625280]
EC50 2.9e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
26
[SID103705684]
[CID44627899]
Ki 3e-05Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells [AID445096, Type: Literature] [gi:116242691]
View
27
[SID103328773]
[CID44337800]
Ki 3e-05Ratio of kappa/delta-opioid receptors Binding affinity [AID228131, Type: Literature] [gi:116242691]
View
28
[SID164132792]
[CID71624554]
EC50 3.1e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
29
[SID164149698]
[CID71625148]
Ki 3.3e-05Displacement of [3H]-diprenorphine from human KOR expressed in CHO cells [AID735689, Type: Literature] [gi:116242691]
View
30
[SID103230838]
[CID5359966]
Ki 3.4e-05Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting [AID670111, Type: Literature] [gi:116242691]
View
31
[SID103230838]
[CID5359966]
Ki 3.4e-05Displacement of [3H]U-69593 from human kappa opioid receptors expressed in CHO cell membrane [AID290257, Type: Literature] [gi:116242691]
View
32
[SID103230838]
[CID5359966]
Ki 3.4e-05Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO membrane [AID296054, Type: Literature] [gi:116242691]
View
33
[SID103230838]
[CID5359966]
Ki 3.4e-05Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells [AID445096, Type: Literature] [gi:116242691]
View
34
[SID103242977]
[CID44299063]
Ki 3.4e-05Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells [AID259396, Type: Literature] [gi:116242691]
View
35
[SID103230838]
[CID5359966]
Ki 3.4e-05Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting [AID592432, Type: Literature] [gi:116242691]
View
36
[SID164146755]
[CID71625150]
EC50 3.5e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
37
[SID131283791]
[CID5360515]
Ki 4e-05Ratio of kappa/delta-opioid receptors Binding affinity [AID228131, Type: Literature] [gi:116242691]
View
38
[SID103215239]
[CID3082718]
Ki 4e-05Inhibitory constant against human Opioid receptor kappa using [3H]diprenorphine as radio ligand [AID238876, Type: Literature] [gi:116242691]
View
39
[SID103328085]
[CID4545429]
Ki 4e-05Binding affinity for human Opioid receptor kappa 1 [AID238630, Type: Literature] [gi:116242691]
View
40
[SID103328370]
[CID44337613]
Ki 4e-05Ratio of kappa/delta-opioid receptors Binding affinity [AID228131, Type: Literature] [gi:116242691]
View
41
[SID164132793]
[CID71624556]
EC50 4.1e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
42
[SID164132789]
[CID71625394]
Ki 4.1e-05Displacement of [3H]-diprenorphine from human KOR expressed in CHO cells [AID735689, Type: Literature] [gi:116242691]
View
43
[SID164149698]
[CID71625148]
EC50 4.2e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
44
[SID103594543]
[CID24822299]
Ki 4.3e-05Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counter [AID395280, Type: Literature] [gi:116242691]
View
45
[SID103215239]
[CID3082718]
Ki 4.3e-05In vitro binding affinity for human kappa opioid receptor was determined by using [3H]diprenorphine as radioligand [AID239438, Type: Literature] [gi:116242691]
View
46
[SID103215239]
[CID3082718]
Ki 4.4e-05Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO-K1 cells [AID331198, Type: Literature] [gi:116242691]
View
47
[SID103524965]
[CID44427178]
Ki 4.6e-05Displacement of [3H]U-69593 from human kappa opioid receptors expressed in CHO cell membrane [AID290257, Type: Literature] [gi:116242691]
View
48
[SID103705546]
[CID44627900]
Ki 4.7e-05Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells [AID445096, Type: Literature] [gi:116242691]
View
49
[SID164129949]
[CID71625281]
EC50 4.7e-05Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID735221, Type: Literature] [gi:116242691]
View
50
[SID164144043]
[CID71625395]
Ki 4.7e-05Displacement of [3H]-diprenorphine from human KOR expressed in CHO cells [AID735689, Type: Literature] [gi:116242691]
View