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BioActivity Data for Gene MDM2 (Gene ID:4193)

Also known as: ACTFS, HDMX, hdm2.
BioActivity Outcomes:
Active(17688)
 
 
Inactive(534137)
 
 
Inconclusive(17)
 
 
Unspecified(323)
 
 
BioAssay Types:
Screening(550464)
 
 
 
Literature(1371)
 
 
 
 
 
Confirmatory(328)
 
 
 
 
 
BioAssay Categories:
Biochemical(1333)
 
 
 
 
 
Cell-based(246)
 
 
 
 
 
Toxicity(3)
 
 
BioActivity Types:
IC50(1041)
 
 
 
 
 
EC50(280)
 
 
 
Ki(133)
 
 
 
 
Kd(38)
 
 
 
 
Substance Types:
Chemical(552149)
 
 
 
 
 
RNAi(16)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 217    Data Row: 552165   Total Pages: 27609   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID194161063]
[CID68000593]
Kd 3.6e-05Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli after 1 to 2 mins by surface plasmon resonance spectroscopic analysis [AID1128403, Type: Literature] [gi:266516]
View
2
[SID194188518]
[CID58573469]
Kd 4.5e-05Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assay [AID1075196, Type: Literature] [gi:266516]
View
3
[SID194174803]
[CID76329003]
IC50 0.0001Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay [AID1075194, Type: Literature] [gi:266516]
View
4
[SID194161063]
[CID68000593]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
5
[SID242623148]
[CID90655377]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
6
[SID242623444]
[CID90655385]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
7
[SID242623452]
[CID90655406]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
8
[SID194174783]
[CID68001087]
IC50 0.0001Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay [AID1075194, Type: Literature] [gi:266516]
View
9
[SID242623443]
[CID90655398]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
10
[SID242623451]
[CID90655405]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
11
[SID242623450]
[CID90655404]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
12
[SID242623426]
[CID90655382]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
13
[SID194174782]
[CID76328992]
IC50 0.0001Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay [AID1075194, Type: Literature] [gi:266516]
View
14
[SID194161064]
[CID76321813]
IC50 0.0001Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay [AID1075194, Type: Literature] [gi:266516]
View
15
[SID242623145]
[CID90655374]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
16
[SID242623425]
[CID90655381]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
17
[SID242623441]
[CID90655396]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View
18
[SID194161063]
[CID68000593]
IC50 0.0001Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay [AID1075194, Type: Literature] [gi:266516]
View
19
[SID194181677]
[CID76332677]
IC50 0.0001Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay [AID1075194, Type: Literature] [gi:266516]
View
20
[SID242623144]
[CID73386675]
IC50 0.0001Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli assessed as inhibition of interaction with p53 in serum free buffer incubated for 20 mins prior to p53 addition measured after 60 mins by HTRF assay [AID1129363, Type: Literature] [gi:266516]
View