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MDM2 (geneid:4193) - Gene BioActivity Data
Also known as: ACTFS, HDMX, hdm2.
BioActivity Outcomes:
Active(17284)
 
 
Inactive(534121)
 
 
Inconclusive(16)
 
 
Unspecified(266)
 
 
BioAssay Types:
Screening(550460)
 
 
 
Literature(911)
 
 
 
 
 
Confirmatory(314)
 
 
 
BioActivity Types:
IC50(654)
 
 
 
 
 
EC50(280)
 
 
 
Ki(85)
 
 
 
 
Kd(19)
 
 
Substance Types:
Chemical(551678)
 
 
 
 
 
RNAi(9)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 172    Data Row: 551687   Total Pages: 27585   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID174512652]
[CID53358942]
Kd 0.00015Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assay [AID1075196, Type: Literature] [gi:266516]
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2
[SID160701617]
[CID56965957]
Kd 0.0004Binding affinity to human MDM2 by surface plasmon resonance binding assay [AID671964, Type: Literature] [gi:266516]
View
3
[SID160701617]
[CID56965957]
Kd 0.0004Binding affinity to human MDM2 by SPR analysis [AID706611, Type: Literature] [gi:266516]
View
4
[SID160701617]
[CID56965957]
Kd 0.0004Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assay [AID1075196, Type: Literature] [gi:266516]
View
5
[SID174507369]
[CID53477213]
Ki 0.00044Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
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6
[SID174496944]
[CID71747669]
Ki 0.00061Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
View
7
[SID174496945]
[CID71745133]
Ki 0.00062Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
View
8
[SID174512482]
[CID71747853]
Ki 0.00062Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
View
9
[SID174496943]
[CID69498017]
Ki 0.00086Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
View
10
[SID163331640]
[CID67998380]
IC50 0.0009Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:266516]
View
11
[SID174486835]
[CID71747852]
Ki 0.00094Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
View
12
[SID174502163]
[CID53477213]
Ki 0.00097Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
View
13
[SID160690851]
[CID56591154]
Kd 0.001Binding affinity to human MDM2 by SPR analysis [AID706611, Type: Literature] [gi:266516]
View
14
[SID160701617]
[CID56965957]
IC50 0.0011Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assay [AID1075194, Type: Literature] [gi:266516]
View
15
[SID160701617]
[CID56965957]
IC50 0.0011Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:266516]
View
16
[SID174512481]
[CID71747669]
Ki 0.0011Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assay [AID756869, Type: Literature] [gi:266516]
View
17
[SID163317819]
[CID58573876]
IC50 0.0017Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:266516]
View
18
[SID163314357]
[CID60154126]
IC50 0.0018Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:266516]
View
19
[SID17387810]
[CID1000056]
EC50 0.0021E3 Ligase dose-response_384 [AID1394, Type: confirmatory] [gi:89993689]
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20
[SID160690851]
[CID56591154]
IC50 0.0022Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature] [gi:266516]
View