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BioActivity Data for Gene AR (Gene ID:367)

Also known as: AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM.
BioActivity Outcomes:
Active(6263)
 
 
Inactive(62822)
 
 
Inconclusive(12957)
 
 
Unspecified(1626)
 
 
BioAssay Types:
Confirmatory(47700)
 
 
 
 
 
Summary(31458)
 
 
 
 
Literature(4447)
 
 
 
 
 
Screening(22)
 
 
 
 
BioAssay Categories:
Biochemical(241)
 
 
 
 
 
Cell-based(205)
 
 
 
 
 
Toxicity(3)
 
 
ADME(27)
 
 
 
In vitro(24)
 
 
 
BioActivity Types:
Potency(79118)
 
 
 
 
IC50(1647)
 
 
 
 
 
Ki(659)
 
 
 
 
 
EC50(329)
 
 
 
 
Kd(13)
 
 
Substance Types:
Chemical(83654)
 
 
 
 
 
RNAi(14)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 504    Data Row: 83668   Total Pages: 4184   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103455152]
[CID10472575]
IC50 9e-06Inhibition of AR-dimerization in CHO-K1 cells expressing human androgen receptor [AID242094, Type: Literature] [gi:113830]
View
2
[SID103447644]
[CID44392243]
Ki 1e-05Binding affinity for mutant T877A Androgen receptor in human LNCaP cells [AID253455, Type: Literature] [gi:113830]
View
3
[SID103537871]
[CID24180647]
IC50 2e-05Antagonist activity against human androgen receptor expressed in human MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced effect by luciferase receptor gene assay [AID389975, Type: Literature] [gi:113830]
View
4
[SID103537871]
[CID24180647]
IC50 2e-05Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assay [AID301208, Type: Literature] [gi:113830]
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5
[SID242625099]
[CID90655075]
EC50 3.9e-05Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay [AID1128317, Type: Literature] [gi:113830]
View
6
[SID123099348]
[CID10635]
IC50 5e-05Activity at androgen receptor in human Saos2 cells assessed as IL6 repression [AID319592, Type: Literature] [gi:113830]
View
7
[SID242625098]
[CID90655074]
EC50 6e-05Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay [AID1128317, Type: Literature] [gi:113830]
View
8
[SID242625095]
[CID90655071]
EC50 7.4e-05Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay [AID1128317, Type: Literature] [gi:113830]
View
9
[SID164142695]
[CID71550737]
EC50 0.0001Agonist activity at androgen receptor (unknown origin) expressed in HeLa cells co-expressing PSA-(ARE)4-Luc13 assessed as induction of DHT-induced luciferase activity after 20 mins by luciferase reporter gene assay [AID729242, Type: Literature] [gi:113830]
View
10
[SID103455152]
[CID10472575]
IC50 0.0001Inhibition of human androgen receptor expressed in Escherichia coli [AID242138, Type: Literature] [gi:113830]
View
11
[SID242619826]
[CID90655082]
EC50 0.00011Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay [AID1128317, Type: Literature] [gi:113830]
View
12
[SID242625099]
[CID90655075]
EC50 0.00014Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by androgenic assay [AID1128318, Type: Literature] [gi:113830]
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13
[SID164142698]
[CID71523527]
EC50 0.00014Agonist activity at androgen receptor (unknown origin) expressed in HeLa cells co-expressing PSA-(ARE)4-Luc13 assessed as induction of DHT-induced luciferase activity after 20 mins by luciferase reporter gene assay [AID729242, Type: Literature] [gi:113830]
View
14
[SID103163840]
[CID3715]
EC50 0.00014Agonist activity at androgen receptor (unknown origin) expressed in HeLa cells co-expressing PSA-(ARE)4-Luc13 assessed as induction of DHT-induced luciferase activity after 20 mins by luciferase reporter gene assay [AID729242, Type: Literature] [gi:113830]
View
15
[SID164142697]
[CID57563344]
EC50 0.00015Agonist activity at androgen receptor (unknown origin) expressed in HeLa cells co-expressing PSA-(ARE)4-Luc13 assessed as induction of DHT-induced luciferase activity after 20 mins by luciferase reporter gene assay [AID729242, Type: Literature] [gi:113830]
View
16
[SID242625094]
[CID90655070]
EC50 0.00015Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay [AID1128317, Type: Literature] [gi:113830]
View
17
[SID103500322]
[CID11560224]
EC50 0.0002Agonist activity at human androgen receptor in CV1 cells measured as stimulation of luciferase reporter gene activity by cotransfection assay [AID272946, Type: Literature] [gi:113830]
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18
[SID103500322]
[CID11560224]
EC50 0.0002Agonist activity at human androgen receptor by luciferase reporter gene assay [AID298545, Type: Literature] [gi:113830]
View
19
[SID103525144]
[CID44427279]
EC50 0.0002Agonist activity at human androgen receptor expressed in CV1 cells [AID290227, Type: Literature] [gi:113830]
View
20
[SID123099348]
[CID10635]
Ki 0.0002Binding affinity to human AR [AID298549, Type: Literature] [gi:113830]
View