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HNF4A (geneid:3172) - Gene BioActivity Data
Also known as: RP5-1013A22.1, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14.
BioActivity Outcomes:
Active(1918)
 
 
Inactive(712)
 
 
Unspecified(14)
 
 
BioAssay Types:
Screening(2267)
 
 
 
Confirmatory(336)
 
 
 
Literature(38)
 
 
 
 
BioActivity Types:
IC50(336)
 
 
 
EC50(8)
 
 
 
Substance Types:
Chemical(2633)
 
 
 
 
RNAi(11)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 26    Data Row: 2644   Total Pages: 133   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID121282725]
[CID51358972]
IC50 0.81365Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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2
[SID125306005]
[CID53383332]
IC50 0.81658Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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3
[SID99357620]
[CID288873]
IC50 0.82821Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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4
[SID125305822]
[CID53383152]
IC50 0.97Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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5
[SID160657964]
[CID32080031]
IC50 1.145Late stage counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization (ROUND 2) [AID652123, Type: confirmatory] [gi:31077205]
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6
[SID103165148]
[CID56909]
EC50 1.22Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells co-transfected with LexADBD assessed as increase in transcriptional activity after 16 hrs by beta-galactosidase one hybrid assay [AID455458, Type: Literature] [gi:148886624]
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7
[SID103165383]
[CID55508]
EC50 1.28Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells co-transfected with LexADBD assessed as increase in transcriptional activity after 16 hrs by beta-galactosidase one hybrid assay [AID455458, Type: Literature] [gi:148886624]
View
8
[SID125305834]
[CID53383164]
IC50 1.303Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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9
[SID125305843]
[CID53383173]
IC50 1.341Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
View
10
[SID160657938]
[CID16446691]
IC50 1.348Late stage counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization (ROUND 2) [AID652123, Type: confirmatory] [gi:31077205]
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11
[SID160657963]
[CID2989871]
IC50 1.376Late stage counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization (ROUND 2) [AID652123, Type: confirmatory] [gi:31077205]
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12
[SID26664761]
[CID312601]
IC50 1.38Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
View
13
[SID125306016]
[CID53383343]
IC50 1.401Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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14
[SID24797084]
[CID6403907]
IC50 1.417Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
View
15
[SID103165400]
[CID100603]
EC50 1.47Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells co-transfected with LexADBD assessed as increase in transcriptional activity after 16 hrs by beta-galactosidase one hybrid assay [AID455458, Type: Literature] [gi:148886624]
View
16
[SID125306020]
[CID53383347]
IC50 1.475Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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17
[SID125306004]
[CID53383331]
IC50 1.483Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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18
[SID22408699]
[CID2423595]
IC50 1.506Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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19
[SID22409494]
[CID6377798]
IC50 1.556Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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20
[SID24803540]
[CID1908237]
IC50 1.588Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization [AID651720, Type: confirmatory] [gi:31077205]
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