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GSR (geneid:2936) - Gene BioActivity Data
Also known as: HEL-75.
BioActivity Outcomes:
Active(48)
 
 
Inactive(58)
 
 
Inconclusive(2)
 
 
Unspecified(75)
 
 
BioAssay Types:
Literature(129)
 
 
 
 
Confirmatory(53)
 
 
 
BioActivity Types:
IC50(87)
 
 
 
Potency(53)
 
 
 
Ki(11)
 
 
 
Substance Types:
Chemical(176)
 
 
 
 
 
RNAi(7)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 50    Data Row: 183   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160696715]
IC50 0.001Inhibitory concentration against human glutathione reductase [AID254839, Type: Literature] [gi:14916998]
View
2
[SID103347788]
[CID11595259]
IC50 0.0041Inhibitory concentration against human glutathione reductase [AID254839, Type: Literature] [gi:14916998]
View
3
[SID134442633]
[CID2724179]
Ki 0.211Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis [AID617312, Type: Literature] [gi:14916998]
View
4
[SID134442633]
[CID2724179]
IC50 0.344Inhibition of human erythrocyte Glutathione reductase [AID617311, Type: Literature] [gi:14916998]
View
5
[SID103372348]
[CID10708341]
IC50 2.7Inhibitory concentration against human glutathione reductase in the the presence of 200 uM exogenous NADP [AID242434, Type: Literature] [gi:14916998]
View
6
[SID103372348]
[CID10708341]
IC50 2.7Inhibitory concentration against human glutathione reductase in the absence of glucose-6-phosphate dehydrogenase (G6PDH) [AID242621, Type: Literature] [gi:14916998]
View
7
[SID103372348]
[CID10708341]
IC50 3.2Inhibitory concentration against human glutathione reductase [AID241335, Type: Literature] [gi:14916998]
View
8
[SID103372348]
[CID10708341]
Ki 3.7Inhibitory concentration against human glutathione reductase [AID238539, Type: Literature] [gi:14916998]
View
9
[SID134458071]
[CID56678909]
Ki 4.16Non-Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis [AID617313, Type: Literature] [gi:14916998]
View
10
[SID134438752]
[CID40727263]
Ki 4.57Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis [AID617312, Type: Literature] [gi:14916998]
View
11
[SID103513606]
[CID11665560]
IC50 5Inhibition of human glutathione reductase after 5 mins pre-incubation with NADPH in presence of 500 uM GSSG substrate [AID282990, Type: Literature] [gi:14916998]
View
12
[SID103568829]
[CID6099]
Km 6.3Activity at human recombinant glutathione reductase at pH 6.9 [AID423544, Type: Literature] [gi:14916998]
View
13
[SID103753590]
[CID44511333]
IC50 6.81Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
14
[SID103682267]
[CID45267884]
IC50 7.13Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
15
[SID103692802]
[CID45273032]
IC50 7.17Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
16
[SID124968087]
[CID11588031]
IC50 7.6Inhibition of human glutathione reductase by spectrophotometer [AID580672, Type: Literature] [gi:14916998]
View
17
[SID103685715]
[CID45269616]
IC50 8.1Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
18
[SID103682266]
[CID45267883]
IC50 8.71Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
19
[SID103690973]
[CID45272169]
IC50 10.3Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
20
[SID103683961]
[CID45268768]
IC50 11Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
21
[SID103181569]
[CID4055]
Ki 12.1Inhibitory concentration against human glutathione reductase (In presence of glutathione disulfide) [AID239442, Type: Literature] [gi:14916998]
View
22
[SID134438752]
[CID40727263]
IC50 13.3Inhibition of human erythrocyte Glutathione reductase [AID617311, Type: Literature] [gi:14916998]
View
23
[SID103692792]
[CID45273021]
IC50 14.2Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
24
[SID134458071]
[CID56678909]
IC50 15.4Inhibition of human erythrocyte Glutathione reductase [AID617311, Type: Literature] [gi:14916998]
View
25
[SID103692791]
[CID45273020]
IC50 16Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
26
[SID103568829]
[CID6099]
IC50 16Inhibitory concentration against human glutathione reductase [AID241792, Type: Literature] [gi:14916998]
View
27
[SID103181569]
[CID4055]
Ki 16.1Inhibitory concentration against human glutathione reductase (In presence of NADPH) [AID239237, Type: Literature] [gi:14916998]
View
28
[SID103568829]
[CID6099]
IC50 16.4Inhibition of human recombinant glutathione reductase at pH 6.9 [AID423559, Type: Literature] [gi:14916998]
View
29
[SID103557046]
[CID4485]
Ki 17.4Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis [AID617312, Type: Literature] [gi:14916998]
View
30
[SID103513606]
[CID11665560]
IC50 18.5Inhibition of human glutathione reductase in presence of 50 uM GSSG substrate [AID282989, Type: Literature] [gi:14916998]
View
31
[SID103676527]
[CID458984]
IC50 20.3Inhibition of human GR [AID298762, Type: Literature] [gi:14916998]
View
32
[SID103675809]
[CID20788690]
IC50 20.4Inhibition of human GR [AID298762, Type: Literature] [gi:14916998]
View
33
[SID103683960]
[CID10964817]
IC50 21Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
34
[SID103458682]
[CID11290283]
IC50 22.7Inhibitory concentration against human glutathione reductase [AID241792, Type: Literature] [gi:14916998]
View
35
[SID103163815]
[CID5281855]
IC50 22.8Inhibition of human glutathione reductase by spectrophotometer [AID580672, Type: Literature] [gi:14916998]
View
36
[SID103683959]
[CID45268767]
IC50 23Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
37
[SID103557046]
[CID4485]
IC50 23.4Inhibition of human erythrocyte Glutathione reductase [AID617311, Type: Literature] [gi:14916998]
View
38
[SID103679442]
[CID2836776]
IC50 24.9Inhibition of human GR [AID298762, Type: Literature] [gi:14916998]
View
39
[SID124965386]
[CID5384468]
IC50 26.7Inhibition of human glutathione reductase by spectrophotometer [AID580672, Type: Literature] [gi:14916998]
View
40
[SID103458585]
[CID11416788]
IC50 27Inhibitory concentration against human glutathione reductase [AID241792, Type: Literature] [gi:14916998]
View
41
[SID103680524]
[CID45266944]
IC50 29Inhibition of human erythrocyte glutathione reductase [AID420294, Type: Literature] [gi:14916998]
View
42
[SID103181569]
[CID4055]
Km 31.2Michaelis menton constant against human glutathione reductase [AID239743, Type: Literature] [gi:14916998]
View
43
[SID103700477]
[CID10352496]
IC50 35.2Inhibition of human recombinant GR after 15 mins in presence of NADPH [AID438771, Type: Literature] [gi:14916998]
View
44
[SID103700542]
[CID25269388]
IC50 35.7Inhibition of human recombinant GR after 15 mins in presence of NADPH [AID438771, Type: Literature] [gi:14916998]
View
45
[SID103699331]
[CID33032]
Ki 42.7Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis [AID617312, Type: Literature] [gi:14916998]
View
46
[SID103700575]
[CID25269732]
IC50 45.3Inhibition of human recombinant GR after 15 mins in presence of NADPH [AID438771, Type: Literature] [gi:14916998]
View
47
[SID103173718]
[CID2578]
Glutathione reductase inhibitor [AID742965, Type: other] [gi:14916998]
View
48
[SID160774639]
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library) [AID651811, Type: Literature] [geneid:2936]
View
49
[SID103700577]
[CID25269394]
IC50 50Inhibition of human recombinant GR after 15 mins in presence of NADPH [AID438771, Type: Literature] [gi:14916998]
View
50
[SID103700587]
[CID25269392]
IC50 50Inhibition of human recombinant GR after 15 mins in presence of NADPH [AID438771, Type: Literature] [gi:14916998]
View