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NR3C1 (geneid:2908) - Gene BioActivity Data
Also known as: GCCR, GCR, GR, GRL.
BioActivity Outcomes:
Active(4359)
 
 
Inactive(55892)
 
 
Inconclusive(10607)
 
 
Unspecified(2971)
 
 
BioAssay Types:
Confirmatory(47268)
 
 
 
 
 
Summary(20972)
 
 
 
 
Literature(5530)
 
 
 
 
 
Screening(20)
 
 
 
 
BioActivity Types:
Potency(37174)
 
 
 
 
IC50(2484)
 
 
 
 
 
EC50(1021)
 
 
 
 
 
Ki(632)
 
 
 
 
Substance Types:
Chemical(73816)
 
 
 
 
 
RNAi(13)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 532    Data Row: 73829   Total Pages: 3692   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103539175]
[CID444036]
IC50 7.5e-05Transrepression activity at glucocorticoid receptor in human H292 cells assessed as inhibition of TNF-stimulated IL-6 cytokine synthesis [AID629915, Type: Literature] [gi:121069]
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2
[SID124966655]
[CID53321912]
IC50 7.94e-05Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay [AID568216, Type: Literature] [gi:121069]
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3
[SID104234229]
[CID5743]
ED50 0.0001Activity at human glucocorticoid receptor expressed in CV1 cells assessed as repression of TNF and IL-1-beta-induced E-selectin gene expression by luciferase reporter gene assay [AID330359, Type: Literature] [gi:121069]
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4
[SID103527549]
[CID17758234]
EC50 0.0001Agonist activity at human GR expressed in CV1 cells by GRE activation assay [AID297837, Type: Literature] [gi:121069]
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5
[SID103507979]
[CID44420057]
IC50 0.0001Binding affinity to human GR [AID276767, Type: Literature] [gi:121069]
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6
[SID103281800]
[CID9820558]
Ki 0.0001Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptor [AID74223, Type: Literature] [gi:121069]
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7
[SID103282420]
[CID44317747]
Ki 0.0001Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptor [AID74223, Type: Literature] [gi:121069]
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8
[SID123086577]
[CID55245]
Ki 0.0001Inhibition of human glucocorticoid receptor [AID238476, Type: Literature] [gi:121069]
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9
[SID103282420]
[CID44317747]
Ki 0.0001Displacement of [3H]DEX from human glucocorticoid receptor [AID473409, Type: Literature] [gi:121069]
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10
[SID103281800]
[CID9820558]
Ki 0.0001Displacement of [3H]DEX from human glucocorticoid receptor [AID473409, Type: Literature] [gi:121069]
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11
[SID174488365]
[CID72736045]
EC50 0.0001Transactivation of glucocorticoid receptor ligand binding domain (unknown origin) transfected in human HeLa cells assessed as activation of NP-1 by GAL4 luciferase reporter gene assay [AID770291, Type: Literature] [gi:121069]
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12
[SID103454385]
[CID44396329]
Ki 0.00011Inhibition of human glucocorticoid receptor [AID238476, Type: Literature] [gi:121069]
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13
[SID124958765]
[CID53317966]
IC50 0.000126Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay [AID568216, Type: Literature] [gi:121069]
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14
[SID103454185]
[CID44396253]
Ki 0.00016Inhibition of human glucocorticoid receptor [AID238476, Type: Literature] [gi:121069]
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15
[SID103281799]
[CID9819614]
Ki 0.00017Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptor [AID74224, Type: Literature] [gi:121069]
View
16
[SID103281799]
[CID9819614]
Ki 0.00017Displacement of [3H]DEX from human glucocorticoid receptor [AID473409, Type: Literature] [gi:121069]
View
17
[SID160676237]
[CID70685018]
Ki 0.00017Inhibition of human glucocorticoid receptor [AID238476, Type: Literature] [gi:121069]
View
18
[SID103454186]
[CID44396254]
Ki 0.00018Inhibition of human glucocorticoid receptor [AID238476, Type: Literature] [gi:121069]
View
19
[SID103527538]
[CID11213029]
EC50 0.0002Agonist activity at human GR expressed in CV1 cells by GRE activation assay [AID297837, Type: Literature] [gi:121069]
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20
[SID103527539]
[CID11155441]
EC50 0.0002Agonist activity at human GR expressed in CV1 cells by GRE activation assay [AID297837, Type: Literature] [gi:121069]
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