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NR5A2 (geneid:2494) - Gene BioActivity Data
Also known as: B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2.
BioActivity Outcomes:
Active(2655)
 
 
Inactive(364341)
 
 
Unspecified(56)
 
 
BioAssay Types:
Screening(366487)
 
 
 
Confirmatory(355)
 
 
 
Literature(147)
 
 
 
 
BioActivity Types:
IC50(355)
 
 
 
EC50(70)
 
 
 
 
Substance Types:
Chemical(367045)
 
 
 
 
RNAi(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 26    Data Row: 367052   Total Pages: 7342   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103501333]
[CID24825422]
EC50 0.012Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
2
[SID160644425]
[CID4789729]
IC50 0.0164Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
3
[SID103501320]
[CID11132282]
EC50 0.022Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
4
[SID103501357]
[CID24825437]
EC50 0.03Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
5
[SID103501444]
[CID24825431]
EC50 0.03162Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
6
[SID103501444]
[CID24825431]
EC50 0.034Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
7
[SID103501366]
[CID24825425]
EC50 0.06Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
8
[SID103501422]
[CID24825428]
EC50 0.07Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
9
[SID103501310]
[CID24825421]
EC50 0.09Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
10
[SID103501356]
[CID24825424]
EC50 0.1Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
11
[SID131278911]
[CID52937033]
EC50 0.1Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
12
[SID93375307]
[CID45382271]
Average IC50 0.11Center Based Initiative to identify novel inverse agonists of the liver receptor homolog-1 (LRH1; NR5A2): Luminescence-based dose response assay to identify LRH1 inhibitors (Cyp19 aromatase-luciferase reporter) [AID488782, Type: confirmatory] [gi:4504343]
View
13
[SID26727554]
[CID9566278]
IC50 0.14349Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
14
[SID49640875]
[CID958637]
IC50 0.14761Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
15
[SID160644426]
[CID774017]
IC50 0.14762Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
16
[SID160644434]
[CID952237]
IC50 0.14762Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
17
[SID103501321]
[CID24825434]
EC50 0.15Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
18
[SID131272874]
[CID52937355]
EC50 0.15849Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
19
[SID103501344]
[CID24825423]
EC50 0.16Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
20
[SID49825032]
[CID8069390]
IC50 0.16785Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
21
[SID57256177]
[CID4789729]
IC50 0.16881Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
22
[SID26730794]
[CID9566279]
IC50 0.19793Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
23
[SID131282925]
[CID52937353]
EC50 0.19953Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
24
[SID103501454]
[CID24825432]
EC50 0.23Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
25
[SID131284888]
[CID52937450]
EC50 0.25119Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
26
[SID131276891]
[CID52937246]
EC50 0.25119Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
27
[SID131272875]
[CID54580360]
EC50 0.25119Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
28
[SID131272872]
[CID52937034]
EC50 0.25119Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
29
[SID131274842]
[CID52936713]
EC50 0.25119Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
30
[SID49821770]
[CID4911805]
IC50 0.29186Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
31
[SID131276887]
[CID52937035]
EC50 0.31623Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
32
[SID131278913]
[CID52937447]
EC50 0.31623Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
33
[SID92092843]
[CID45100448]
Average IC50 0.32Center Based Initiative to identify novel inverse agonists of the liver receptor homolog-1 (LRH1; NR5A2): Luminescence-based dose response assay to identify LRH1 inhibitors (Cyp19 aromatase-luciferase reporter) [AID488782, Type: confirmatory] [gi:4504343]
View
34
[SID103501431]
[CID24825429]
EC50 0.32Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
35
[SID103501334]
[CID24825435]
EC50 0.33Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
36
[SID160644473]
[CID2948274]
IC50 0.38559Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
37
[SID131278914]
[CID52936816]
EC50 0.39811Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
38
[SID131286941]
[CID52937449]
EC50 0.39811Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature] [gi:7676156]
View
39
[SID92092844]
[CID45100455]
Average IC50 0.43Center Based Initiative to identify novel inverse agonists of the liver receptor homolog-1 (LRH1; NR5A2): Luminescence-based dose response assay to identify LRH1 inhibitors (Cyp19 aromatase-luciferase reporter) [AID488782, Type: confirmatory] [gi:4504343]
View
40
[SID103501294]
[CID10883540]
EC50 0.43Binding affinity to human LRH1 by FRET-based peptide recruitment assay [AID271721, Type: Literature] [gi:7676156]
View
41
[SID3712332]
[CID2094416]
IC50 0.43717Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
42
[SID17414198]
[CID1287749]
IC50 0.44283Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory] [gi:4504343]
View
43
[SID160644493]
[CID24892601]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
44
[SID160644484]
[CID4147163]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
45
[SID160644485]
[CID7502918]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
46
[SID160644486]
[CID7855787]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
47
[SID160644503]
[CID2089406]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
48
[SID160644415]
[CID24892565]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
49
[SID160644457]
[CID958637]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View
50
[SID160644465]
[CID4905846]
IC50 0.44285Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory] [gi:4504343]
View