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BioActivity Data for Gene EPHX2 (Gene ID:2053)

Also known as: CEH, SEH.
BioActivity Outcomes:
Active(1785)
 
 
Inactive(181218)
 
 
Inconclusive(52)
 
 
Unspecified(180)
 
 
BioAssay Types:
Screening(181302)
 
 
 
Literature(1587)
 
 
 
 
 
Confirmatory(311)
 
 
 
BioActivity Types:
IC50(1819)
 
 
 
 
 
EC50(9)
 
 
Ki(2)
 
 
Substance Types:
Chemical(183224)
 
 
 
 
 
RNAi(11)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 80    Data Row: 183235   Total Pages: 9162   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103708651]
[CID45487839]
IC50 0.0001Inhibition of soluble EH in human HepG2 cells by cellular assay [AID446441, Type: Literature] [gi:67476665]
View
2
[SID194180530]
[CID71679348]
IC50 0.000125Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as substrate preincubated for 30 mins followed by substrate addition measured after 20 to 45 mins by fluorescence assay [AID1064059, Type: Literature] [gi:67476665]
View
3
[SID103694059]
[CID16725330]
EC50 0.00014Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA [AID431445, Type: Literature] [gi:67476665]
View
4
[SID174519618]
[CID72376135]
IC50 0.0002Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
5
[SID174524894]
[CID72376133]
IC50 0.0002Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
6
[SID174524895]
[CID72376213]
IC50 0.0002Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
7
[SID174493902]
[CID71566536]
IC50 0.0003Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
8
[SID174499049]
[CID72374649]
IC50 0.0003Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
9
[SID174519617]
[CID72376134]
IC50 0.0003Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
10
[SID174504303]
[CID71566538]
IC50 0.0003Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
11
[SID103694058]
[CID44475367]
EC50 0.0003Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA [AID431445, Type: Literature] [gi:67476665]
View
12
[SID103692217]
[CID44475063]
EC50 0.0003Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA [AID431445, Type: Literature] [gi:67476665]
View
13
[SID103681760]
[CID44475368]
EC50 0.0004Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA [AID431445, Type: Literature] [gi:67476665]
View
14
[SID164127927]
[CID71540714]
IC50 0.0004Inhibition of human sEH assessed as 6-methoxy-2-naphthaldehyde generation preincubated for 10 before addition of cyano(2-methyl-oxynaphthalen-6-yl)methyl trans-(3-phenyloxyran-2-yl) methyl carbonate by fluorescence analysis [AID721547, Type: Literature] [gi:67476665]
View
15
[SID103507447]
[CID11596176]
IC50 0.0004Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins by fluorescence analysis [AID661405, Type: Literature] [gi:67476665]
View
16
[SID194173605]
[CID71679838]
IC50 0.0004Inhibition of human recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as substrate preincubated for 30 mins followed by substrate addition measured after 20 to 45 mins by fluorescence assay [AID1064059, Type: Literature] [gi:67476665]
View
17
[SID174509417]
[CID72376212]
IC50 0.0004Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
18
[SID174514591]
[CID71566537]
IC50 0.0004Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
19
[SID174519615]
[CID71522732]
IC50 0.0004Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by fluorescence assay [AID775173, Type: Literature] [gi:67476665]
View
20
[SID134443628]
[CID3754047]
IC50 0.0004Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins by fluorescence analysis [AID661405, Type: Literature] [gi:67476665]
View