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S1PR1 (geneid:1901) - Gene BioActivity Data
Also known as: CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1.
BioActivity Outcomes:
Active(2426)
 
 
Inactive(73352)
 
 
Unspecified(273)
 
 
BioAssay Types:
Screening(72978)
 
 
 
Confirmatory(1822)
 
 
 
 
Literature(955)
 
 
 
 
Summary(3)
 
 
BioActivity Types:
EC50(787)
 
 
 
 
IC50(334)
 
 
 
 
Ki(8)
 
 
Kd(1)
 
 
Substance Types:
Chemical(76044)
 
 
 
 
RNAi(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 134    Data Row: 76051   Total Pages: 1522   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103460256]
[CID11452022]
EC50 1.2e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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2
[SID103745419]
[CID46884020]
EC50 1.8e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
View
3
[SID103513044]
[CID5283560]
EC50 2.7e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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4
[SID103491468]
[CID44412971]
EC50 3e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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5
[SID160704308]
[CID70695743]
EC50 3.98e-05Agonist activity at human S1P1 receptor expressed in human U2OS cells assessed as beta-arrestin-mediated receptor internalization by beta-lactamase reporter assay [AID652657, Type: Literature] [gi:205371820]
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6
[SID103491422]
[CID44412936]
EC50 7e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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7
[SID103745366]
[CID25192001]
EC50 7.7e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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8
[SID103491265]
[CID24825338]
EC50 8e-05Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
View
9
[SID103491179]
[CID11689680]
EC50 8e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
10
[SID103491179]
[CID11689680]
EC50 8e-05Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
View
11
[SID103491625]
[CID11575913]
EC50 8e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
12
[SID103745420]
[CID25192005]
EC50 8.8e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
View
13
[SID103491265]
[CID24825338]
EC50 9e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
14
[SID103491179]
[CID11689680]
EC50 0.0001Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
View
15
[SID103490983]
[CID11626664]
EC50 0.0001Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
16
[SID103491516]
[CID44412994]
EC50 0.0001Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
17
[SID103336777]
[CID44341276]
IC50 0.0001Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID204037, Type: Literature] [gi:205371820]
View
18
[SID103491542]
[CID16038017]
EC50 0.00011Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
19
[SID103547870]
[CID11496072]
EC50 0.00012Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
View
20
[SID103651326]
[CID44591250]
IC50 0.00014Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor [AID392389, Type: Literature] [gi:205371820]
View
21
[SID103460316]
[CID11222939]
EC50 0.00014Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS binding [AID466802, Type: Literature] [gi:205371820]
View
22
[SID103491237]
[CID11603726]
EC50 0.00015Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
View
23
[SID103491208]
[CID44412828]
EC50 0.00016Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
View
24
[SID103336850]
IC50 0.00016Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID204037, Type: Literature] [gi:205371820]
View
25
[SID103337224]
[CID9885762]
IC50 0.00016Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID204037, Type: Literature] [gi:205371820]
View
26
[SID103450933]
[CID44394191]
IC50 0.00016Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID241959, Type: Literature] [gi:205371820]
View
27
[SID103451033]
[CID44394273]
IC50 0.00016Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID241959, Type: Literature] [gi:205371820]
View
28
[SID103513044]
[CID5283560]
IC50 0.00016Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID204037, Type: Literature] [gi:205371820]
View
29
[SID103460316]
[CID11222939]
IC50 0.00016Displacement of [33P]-S1P1 from human S1P1 receptor expressed in CHO cells [AID466807, Type: Literature] [gi:205371820]
View
30
[SID103490934]
[CID11654374]
EC50 0.00018Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
View
31
[SID103491178]
[CID44412813]
EC50 0.0002Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
View
32
[SID103491237]
[CID11603726]
EC50 0.0002Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
33
[SID103491267]
[CID11646599]
EC50 0.0002Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
34
[SID103512956]
[CID10174255]
EC50 0.0002Activity at human S1P1 receptor expressed in CHO cells by [35S]GTPgammaS binding assay [AID282274, Type: Literature] [gi:205371820]
View
35
[SID103595653]
[CID44565739]
IC50 0.0002Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor [AID351684, Type: Literature] [gi:205371820]
View
36
[SID136928502]
[CID57335019]
EC50 0.0002Agonist activity at eGFP-tagged human S1P1 receptor expressed in U2OS cells assessed as receptor internalization after 1 hr by Hoechst dye-based microscopic analysis [AID647953, Type: Literature] [gi:205371820]
View
37
[SID103547872]
[CID44439850]
EC50 0.00021Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
View
38
[SID103595228]
[CID44565597]
IC50 0.00021Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor [AID351684, Type: Literature] [gi:205371820]
View
39
[SID103490984]
[CID44412704]
EC50 0.00023Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
View
40
[SID103748440]
[CID25008420]
IC50 0.00023Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor expressed in HEK293T cells after 60 mins by scintillation counting [AID476457, Type: Literature] [gi:205371820]
View
41
[SID103748376]
[CID46885796]
IC50 0.00024Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor expressed in HEK293T cells after 60 mins by scintillation counting [AID476457, Type: Literature] [gi:205371820]
View
42
[SID160690403]
[CID44138103]
EC50 0.00025Agonist activity against human S1P1 assessed as accumulation of cAMP by HTRF assay [AID671344, Type: Literature] [gi:205371820]
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43
[SID103651376]
[CID44591265]
IC50 0.00026Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor [AID392389, Type: Literature] [gi:205371820]
View
44
[SID103761777]
[CID46905530]
IC50 0.00028Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID241959, Type: Literature] [gi:205371820]
View
45
[SID103491626]
[CID44413039]
EC50 0.00028Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
View
46
[SID103337104]
[CID9908268]
IC50 0.00028Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID204037, Type: Literature] [gi:205371820]
View
47
[SID103337104]
[CID9908268]
IC50 0.00028Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cells [AID282267, Type: Literature] [gi:205371820]
View
48
[SID103460256]
[CID11452022]
IC50 0.00028Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranes [AID553425, Type: other] [gi:205371820]
View
49
[SID136941511]
[CID57401335]
EC50 0.0003Agonist activity at eGFP-tagged human S1P1 receptor expressed in U2OS cells assessed as receptor internalization after 1 hr by Hoechst dye-based microscopic analysis [AID647953, Type: Literature] [gi:205371820]
View
50
[SID103337104]
[CID9908268]
EC50 0.0003Activity at human S1P1 receptor expressed in CHO cells by [35S]GTPgammaS binding assay [AID282274, Type: Literature] [gi:205371820]
View