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BioActivity Data for Gene S1PR1 (Gene ID:1901)

Also known as: CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1.
BioActivity Outcomes:
Active(2692)
 
 
Inactive(73402)
 
 
Unspecified(352)
 
 
BioAssay Types:
Screening(72983)
 
 
 
Confirmatory(1913)
 
 
 
 
Literature(1477)
 
 
 
 
Summary(3)
 
 
BioAssay Categories:
Biochemical(990)
 
 
 
 
Cell-based(18840)
 
 
 
 
Toxicity(3)
 
 
In vitro(145)
 
 
 
 
BioActivity Types:
EC50(1054)
 
 
 
 
IC50(366)
 
 
 
 
Ki(8)
 
 
Kd(1)
 
 
Substance Types:
Chemical(76431)
 
 
 
 
RNAi(15)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 154    Data Row: 76446   Total Pages: 3823   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103460256]
[CID11452022]
EC50 1.2e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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2
[SID103745419]
[CID46884020]
EC50 1.8e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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3
[SID103513044]
[CID5283560]
EC50 2.7e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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4
[SID103491468]
[CID44412971]
EC50 3e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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5
[SID160704308]
[CID70695743]
EC50 3.98e-05Agonist activity at human S1P1 receptor expressed in human U2OS cells assessed as beta-arrestin-mediated receptor internalization by beta-lactamase reporter assay [AID652657, Type: Literature] [gi:205371820]
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6
[SID103491422]
[CID44412936]
EC50 7e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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7
[SID103745366]
[CID25192001]
EC50 7.7e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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8
[SID103491625]
[CID11575913]
EC50 8e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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9
[SID103491179]
[CID11689680]
EC50 8e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
10
[SID103491179]
[CID11689680]
EC50 8e-05Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
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11
[SID103491265]
[CID24825338]
EC50 8e-05Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
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12
[SID103745420]
[CID25192005]
EC50 8.8e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
View
13
[SID103491265]
[CID24825338]
EC50 9e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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14
[SID103490983]
[CID11626664]
EC50 0.0001Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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15
[SID103491516]
[CID44412994]
EC50 0.0001Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
16
[SID103491179]
[CID11689680]
EC50 0.0001Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
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17
[SID103336777]
[CID44341276]
IC50 0.0001Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID204037, Type: Literature] [gi:205371820]
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18
[SID194147327]
[CID76314622]
EC50 0.0001Agonist activity at human recombinant S1P1 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 hr by topcount scintillation counting analysis [AID1073714, Type: Literature] [gi:205371820]
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19
[SID194140491]
[CID76310992]
EC50 0.0001Agonist activity at human recombinant S1P1 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 hr by topcount scintillation counting analysis [AID1073714, Type: Literature] [gi:205371820]
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20
[SID194154186]
[CID68555865]
EC50 0.0001Agonist activity at human recombinant S1P1 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 hr by topcount scintillation counting analysis [AID1073714, Type: Literature] [gi:205371820]
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