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S1PR1 (geneid:1901) - Gene BioActivity Data
Also known as: CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1.
BioActivity Outcomes:
Active(2433)
 
 
Inactive(73354)
 
 
Unspecified(273)
 
 
BioAssay Types:
Screening(72979)
 
 
 
Confirmatory(1962)
 
 
 
 
Literature(960)
 
 
 
 
Summary(3)
 
 
BioActivity Types:
EC50(791)
 
 
 
 
IC50(333)
 
 
 
 
Ki(8)
 
 
Kd(1)
 
 
Substance Types:
Chemical(76052)
 
 
 
 
RNAi(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 144    Data Row: 76060   Total Pages: 3803   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103460256]
[CID11452022]
EC50 1.2e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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2
[SID103745419]
[CID46884020]
EC50 1.8e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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3
[SID103513044]
[CID5283560]
EC50 2.7e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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4
[SID103491468]
[CID44412971]
EC50 3e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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5
[SID160704308]
[CID70695743]
EC50 3.98e-05Agonist activity at human S1P1 receptor expressed in human U2OS cells assessed as beta-arrestin-mediated receptor internalization by beta-lactamase reporter assay [AID652657, Type: Literature] [gi:205371820]
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6
[SID103491422]
[CID44412936]
EC50 7e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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7
[SID103745366]
[CID25192001]
EC50 7.7e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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8
[SID103491625]
[CID11575913]
EC50 8e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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9
[SID103491179]
[CID11689680]
EC50 8e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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10
[SID103491179]
[CID11689680]
EC50 8e-05Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
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11
[SID103491265]
[CID24825338]
EC50 8e-05Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
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12
[SID103745420]
[CID25192005]
EC50 8.8e-05Agonist activity at human S1P1 receptor assessed as effect on calcium mobilization by Gi dependent whole cell assay [AID473717, Type: Literature] [gi:205371820]
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13
[SID103491265]
[CID24825338]
EC50 9e-05Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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14
[SID103491516]
[CID44412994]
EC50 0.0001Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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15
[SID103490983]
[CID11626664]
EC50 0.0001Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
View
16
[SID103491179]
[CID11689680]
EC50 0.0001Agonist activity at S1P1 receptor assessed as induction of [35S]GTP-gamma-S binding [AID268555, Type: Literature] [gi:205371820]
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17
[SID103336777]
[CID44341276]
IC50 0.0001Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes [AID204037, Type: Literature] [gi:205371820]
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18
[SID103491542]
[CID16038017]
EC50 0.00011Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptake [AID268302, Type: Literature] [gi:205371820]
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19
[SID103547870]
[CID11496072]
EC50 0.00012Displacement of [35S]GTPgammaS from human S1P1 receptor expressed in CHO cells [AID305283, Type: Literature] [gi:205371820]
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20
[SID103460316]
[CID11222939]
EC50 0.00014Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS binding [AID466802, Type: Literature] [gi:205371820]
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