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CTSB (geneid:1508) - Gene BioActivity Data
Also known as: APPS, CPSB.
BioActivity Outcomes:
Active(916)
 
 
Inactive(125498)
 
 
Inconclusive(69)
 
 
Unspecified(660)
 
 
BioAssay Types:
Screening(125440)
 
 
 
Literature(1471)
 
 
 
 
 
Confirmatory(158)
 
 
 
 
BioActivity Types:
IC50(903)
 
 
 
 
 
Ki(454)
 
 
 
 
 
Substance Types:
Chemical(127136)
 
 
 
 
 
RNAi(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 168    Data Row: 127143   Total Pages: 2543   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160678338]
[CID10985562]
Ki 3e-05Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
2
[SID103459615]
[CID44398651]
Ki 7.7e-05Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMC [AID239257, Type: Literature] [gi:68067549]
View
3
[SID160699878]
[CID10033311]
Ki 8.8e-05Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
4
[SID160689049]
[CID11061638]
Ki 0.00012Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
5
[SID160694517]
[CID11007209]
Ki 0.00013Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
6
[SID160673007]
[CID10898110]
Ki 0.00025Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
7
[SID103459916]
[CID44398741]
Ki 0.00025Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMC [AID239257, Type: Literature] [gi:68067549]
View
8
[SID160689050]
[CID10887117]
Ki 0.0003Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
9
[SID124969911]
[CID50994142]
Ki 0.00036Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
10
[SID124972506]
[CID50994056]
Ki 0.00038Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
11
[SID103722027]
[CID24897809]
Ki 0.00043Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
12
[SID124967233]
[CID50994055]
Ki 0.00048Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
13
[SID124968203]
[CID50994058]
Ki 0.00065Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
14
[SID103722021]
[CID24898027]
Ki 0.00068Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
15
[SID124964533]
[CID50993974]
Ki 0.00088Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
16
[SID103522963]
[CID16664855]
IC50 0.001Inhibition of human recombinant cathepsin B [AID290151, Type: Literature] [gi:68067549]
View
17
[SID103459612]
[CID44398649]
Ki 0.0013Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMC [AID239257, Type: Literature] [gi:68067549]
View
18
[SID124972507]
[CID50994060]
Ki 0.0013Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
19
[SID124969909]
[CID50994057]
Ki 0.0013Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
20
[SID160678336]
[CID10898089]
Ki 0.00141Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
21
[SID855916]
[CID123664]
IC50 mean 0.00152588Cathepsin B mixture HTS dose-response confirmation [AID830, Type: confirmatory] [gi:63102437]
View
22
[SID160705233]
[CID70696209]
Ki 0.00158Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
23
[SID103570658]
[CID44452938]
Ki 0.002Inhibition of human liver cathepsin B [AID321238, Type: Literature] [gi:68067549]
View
24
[SID103522966]
[CID24901100]
IC50 0.002Inhibition of human recombinant cathepsin B [AID290151, Type: Literature] [gi:68067549]
View
25
[SID103489606]
[CID44412155]
Ki 0.002Inhibition of human cathepsin B [AID266477, Type: Literature] [gi:68067549]
View
26
[SID103446602]
[CID44391474]
IC50 0.0024Inhibitory concentration against human cathepsin B using 10 uM Cbz-Phe-Arg-AMC [AID241949, Type: Literature] [gi:68067549]
View
27
[SID124976380]
[CID50994137]
Ki 0.0024Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
28
[SID124965927]
[CID50994138]
Ki 0.0024Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
29
[SID124969910]
[CID50994059]
Ki 0.0028Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
30
[SID103597366]
[CID44566188]
IC50 0.00311Inhibition of human liver cathepsin B after 30 mins by fluorometric end-point assay [AID350737, Type: Literature] [gi:68067549]
View
31
[SID124975274]
[CID50993973]
Ki 0.0043Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assay [AID554257, Type: Literature] [gi:68067549]
View
32
[SID103522965]
[CID24901099]
IC50 0.005Inhibition of human recombinant cathepsin B [AID290151, Type: Literature] [gi:68067549]
View
33
[SID163316704]
[CID60148519]
Ki 0.0058Inhibition of human cathepsin B using Z-Arg-Arg-pNA as substrate after 80 mins by spectrophotometric analysis [AID691905, Type: Literature] [gi:68067549]
View
34
[SID160705232]
[CID10876251]
Ki 0.00729Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
35
[SID103522967]
[CID24901101]
IC50 0.008Inhibition of human recombinant cathepsin B [AID290151, Type: Literature] [gi:68067549]
View
36
[SID123089573]
[CID42633341]
IC50 0.009Inhibition of human Cat B in HepG2 cells [AID538811, Type: Literature] [gi:68067549]
View
37
[SID124971513]
[CID123985]
IC50 0.01Inhibition of human recombinant cathepsin B after 10 mins [AID360103, Type: Literature] [gi:68067549]
View
38
[SID103604055]
[CID44479637]
IC50 0.011Inhibition of human recombinant cathepsin B [AID339476, Type: Literature] [gi:68067549]
View
39
[SID855920]
[CID439487]
IC50 mean 0.0122833Cathepsin B mixture HTS dose-response confirmation [AID830, Type: confirmatory] [gi:63102437]
View
40
[SID160699877]
[CID11768265]
Ki 0.013Inhibition of Human Cathepsin B [AID50286, Type: Literature] [gi:68067549]
View
41
[SID103531349]
[CID16655063]
IC50 0.013Inhibition of human recombinant cathepsin B [AID293183, Type: Literature] [gi:68067549]
View
42
[SID103481289]
[CID6918602]
Ki 0.013Inhibition of human cathepsin B [AID261377, Type: Literature] [gi:68067549]
View
43
[SID103597365]
[CID44566187]
IC50 0.0142Inhibition of human liver cathepsin B after 30 mins by fluorometric end-point assay [AID350737, Type: Literature] [gi:68067549]
View
44
[SID103468125]
[CID9912381]
IC50 0.017Inhibitory activity against human cathepsin B expressed in HepG2 cells [AID257085, Type: Literature] [gi:68067549]
View
45
[SID103480427]
[CID44408049]
IC50 0.018Inhibition of recombinant human cathepsin B in a fluorescence assay [AID260671, Type: Literature] [gi:68067549]
View
46
[SID103531788]
[CID10146227]
IC50 0.019Inhibition of cathepsin D [AID292706, Type: Literature] [gi:68067549]
View
47
[SID103531761]
[CID44430097]
IC50 0.02Inhibition of cathepsin D [AID292706, Type: Literature] [gi:68067549]
View
48
[SID103531341]
[CID10231379]
IC50 0.02Inhibition of human recombinant cathepsin B [AID293183, Type: Literature] [gi:68067549]
View
49
[SID103484498]
[CID44409753]
Ki 0.02Inhibition of cathepsin B from human brain [AID263485, Type: Literature] [gi:68067549]
View
50
[SID103603996]
[CID44479635]
IC50 0.023Inhibition of human recombinant cathepsin B [AID339476, Type: Literature] [gi:68067549]
View