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blaVIM-2 (geneid:14678525) - Gene BioActivity Data
Also known as: D703_p16.
BioActivity Outcomes:
Probe(6)
 
 
Active(4354)
 
 
Inactive(289584)
 
 
Inconclusive(8)
 
 
Unspecified(108)
 
 
BioAssay Types:
Screening(293423)
 
 
 
Confirmatory(351)
 
 
 
 
Literature(131)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
IC50(348)
 
 
 
 
Ki(3)
 
 
 
 
Substance Types:
Chemical(294060)
 
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 33    Data Row: 294060   Total Pages: 14703   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134220672]
[CID53362017]
Ki 0.183Late stage assay provider results from the probe development efforts to identify nonselective inhibitors of VIM-2 metallo-beta-lactamase: Absorbance-based biochemical assays to determine the ability of probe candidates and selected analogs to inhibit VIM-2 [AID624083, Type: confirmatory] [gi:7381449]
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2
[SID134220672]
[CID53362017]
MIC [4 fold reduction] 0.391Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective): Growth inhibition of clinically relevant VIM-2-transformed Acinetobacter species (YMC07/8/B3323) in the presence of imipenem (synergy) [AID624096, Type: other] [gi:7381449]
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3
[SID125264855]
[CID53362017]
IC50 0.5481Late stage assay provider results from the probe development efforts to identify nonselective inhibitors of VIM-2 metallo-beta-lactamase: Absorbance-based biochemical assays to determine the ability of probe candidates and selected analogs to inhibit VIM-2 [AID624079, Type: confirmatory] [gi:7381449]
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4
[SID125264855]
[CID53362017]
MIC [4 fold reduction] 0.781Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective): Growth inhibition of clinically relevant VIM-2-transformed Acinetobacter species (YMC07/8/B3323) in the presence of imipenem (synergy) [AID624096, Type: other] [gi:7381449]
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5
[SID125264855]
[CID53362017]
MIC [4 fold reduction] 3.125Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective): VIM-2-transformed E. coli growth inhibition in the presence of imipenem (synergy) [AID624081, Type: other] [gi:7381449]
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6
[SID85856282]
[CID4870494]
Summary of probe development efforts to identify selective inhibitors of VIM-2 metallo-beta-lactamase [AID1854, Type: summary] [gi:7381449]
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7
[SID24790728]
[CID4870494]
IC50 0.03394FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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8
[SID24790728]
[CID4870494]
IC50 0.05435Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase [AID1919, Type: confirmatory] [gi:7381449]
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9
[SID24707842]
[CID11834391]
IC50 0.12018FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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10
[SID135383770]
[CID56851709]
MIC [4 fold reduction] 0.195Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective): Growth inhibition of clinically relevant VIM-2-transformed Acinetobacter species (YMC07/8/B3323) in the presence of imipenem (synergy) [AID624096, Type: other] [gi:7381449]
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11
[SID85856282]
[CID4870494]
0.223Late stage results from the probe development efforts to identify selective inhibitors of VIM-2 metallo-beta-lactamase: probe results [AID2128_2, Type: other] [gi:7381449]
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12
[SID26666672]
[CID302501]
IC50 0.24479FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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13
[SID92192479]
[CID45105307]
IC50 0.2454Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of VIM-2 metallo-beta-lactamase [AID2769, Type: confirmatory] [gi:7381449]
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14
[SID47197611]
[CID6863594]
IC50 0.33229FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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15
[SID24837288]
[CID9643280]
IC50 0.33463FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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16
[SID26671366]
[CID1547995]
IC50 0.37361FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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17
[SID49679995]
[CID2818392]
IC50 0.37422Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase [AID2754, Type: confirmatory] [gi:7381449]
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18
[SID49668006]
[CID1427313]
IC50 0.43308FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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19
[SID24707842]
[CID11834391]
IC50 0.45301Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase [AID1919, Type: confirmatory] [gi:7381449]
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20
[SID49822987]
[CID16406937]
IC50 0.525FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory] [gi:7381449]
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