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aurora kinase B isoform 1 [Homo sapiens] [gi:83776600] - Target BioActivity Data
Filters: All Data » Active      
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BioActivity Outcomes:
Active(414)
 
 
BioAssay Types:
Literature(398)
 
 
Confirmatory(16)
 
 
BioActivity Types:
IC50(220)
 
 
Kd(41)
 
 
Ki(37)
 
 
EC50(35)
 
 
AC50(16)
 
 
Substance Types:
Chemical(414)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 66    Data Row: 414   Total Pages: 9   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103748127]
[CID46885626]
Ki 0.00038Competitive inhibition of human Aurora B ATP binding site by rapid dilution method [AID479658, Type: Literature]
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2
[SID103754016]
[CID46888642]
IC50 0.001Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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3
[SID103502373]
[CID10175126]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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4
[SID103502374]
[CID10239873]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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5
[SID103502375]
[CID10153234]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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6
[SID103502376]
[CID10289802]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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7
[SID103502377]
[CID10312249]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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8
[SID103502378]
[CID10311867]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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9
[SID103502379]
[CID10128386]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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10
[SID103502380]
[CID9958417]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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11
[SID103502381]
[CID10239608]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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12
[SID103502383]
[CID10239769]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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13
[SID103502384]
[CID10239891]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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14
[SID103502385]
[CID10196758]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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15
[SID103502385]
[CID10196758]
IC50 0.001Inhibition of aurora B in human SW620 cells assessed as inhibition of histone H3 phosphorylation [AID353654, Type: Literature]
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16
[SID103502386]
[CID16221341]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
View
17
[SID103502387]
[CID16221342]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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18
[SID103502388]
[CID16221343]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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19
[SID103502389]
[CID16007391]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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20
[SID103502390]
[CID16221393]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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21
[SID103502391]
[CID16221394]
Ki 0.001Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
View
22
[SID103754182]
[CID46888746]
IC50 0.0014Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
23
[SID103754228]
[CID46888771]
IC50 0.0015Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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24
[SID103754130]
[CID24816055]
IC50 0.0017Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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25
[SID103757433]
[CID11632150]
Ki 0.002Inhibition of human recombinant Aurora B after 60 mins [AID483577, Type: Literature]
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26
[SID103754017]
[CID46888643]
IC50 0.002Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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27
[SID103748126]
[CID46885625]
IC50 0.002Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
28
[SID103502382]
[CID10311891]
Ki 0.002Inhibition of human recombinant Aurora B [AID273825, Type: Literature]
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29
[SID103754183]
[CID46888747]
IC50 0.0021Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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30
[SID164132841]
[CID5703619]
IC50 0.0023Inhibition of Aurora B (unknown origin) after 10 mins by mobility shift assay [AID739573, Type: Literature]
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31
[SID163330909]
[CID57384257]
EC50 0.003Inhibition of Aurora kinase B in human HCT116 cells assessed as induction of 8N polyploidy [AID698798, Type: Literature]
View
32
[SID163330907]
[CID57384510]
IC50 0.003Inhibition of Aurora kinase B-mediated histone H3 Ser10 phosphorylation in human HCT116 cells after 2 hrs by sandwich ELISA [AID698657, Type: Literature]
View
33
[SID163330907]
[CID57384510]
EC50 0.003Inhibition of Aurora kinase B in human HCT116 cells assessed as induction of 8N polyploidy [AID698798, Type: Literature]
View
34
[SID103754015]
[CID46888641]
IC50 0.003Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
35
[SID103754129]
[CID24815964]
IC50 0.003Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
36
[SID103757434]
[CID11718021]
Ki 0.003Inhibition of human recombinant Aurora B after 60 mins [AID483577, Type: Literature]
View
37
[SID103645273]
[CID10142586]
IC50 0.003Inhibition of human Aurora kinase B/INCEP complex expressed in Escherichia coli BL21 (DE3) using gamma-[32P]ATP incubated for 1 hr by autoradiography [AID706706, Type: Literature]
View
38
[SID103754181]
[CID24815966]
IC50 0.0036Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
39
[SID103757565]
[CID46830768]
Ki 0.0038Inhibition of human recombinant Aurora B after 60 mins [AID483577, Type: Literature]
View
40
[SID103757498]
[CID11646645]
Ki 0.004Inhibition of human recombinant Aurora B after 60 mins [AID483577, Type: Literature]
View
41
[SID103754229]
[CID24816056]
IC50 0.0045Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
42
[SID103502389]
[CID16007391]
Kd 0.0046Binding constant for AURKB kinase domain [AID624772, Type: Literature]
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43
[SID103754231]
[CID24815965]
IC50 0.0047Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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44
[SID103754232]
[CID46888773]
IC50 0.0047Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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45
[SID103754234]
[CID46236622]
IC50 0.005Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
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46
[SID103754236]
[CID46236769]
IC50 0.005Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
47
[SID103754230]
[CID46888772]
IC50 0.005Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
48
[SID103748127]
[CID46885626]
IC50 0.005Inhibition of human Aurora B by rapid dilution method [AID479653, Type: Literature]
View
49
[SID103757435]
[CID11647020]
Ki 0.006Inhibition of human recombinant Aurora B after 60 mins [AID483577, Type: Literature]
View
50
[SID103757501]
[CID10340715]
Ki 0.006Inhibition of human recombinant Aurora B after 60 mins [AID483577, Type: Literature]
View