Bookmark and Share
BioActivity Data for Targets
Filters: All Data » Active      
Filter selected
BioActivity Outcomes:
Active(34)
 
 
BioAssay Types:
Literature(34)
 
 
BioActivity Types:
IC50(30)
 
 
Substance Types:
Chemical(34)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 34   Total Pages: 1   
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103259004]
[CID6918572]
IC50 0.066Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
2
[SID160704911]
[CID66561557]
IC50 0.11Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
3
[SID160694242]
[CID66561555]
IC50 0.126Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
4
[SID123095278]
[CID16040457]
IC50 0.67Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
5
[SID160688741]
[CID66561556]
IC50 0.85Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
6
[SID103680228]
[CID45266496]
Km 1.02Activity of mouse FAP assessed as enzyme mediated drug cleavage by measuring increase in fluorescence intensity [AID347008, Type: Literature]
View
7
[SID160699590]
[CID70693953]
IC50 1.3Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
8
[SID160667411]
[CID70681357]
IC50 1.4Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
9
[SID160699586]
[CID70693949]
IC50 1.9Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
10
[SID160667650]
[CID70681469]
IC50 2.4Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
11
[SID160678049]
[CID70685560]
IC50 2.7Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
12
[SID160699588]
[CID70693951]
IC50 2.7Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
13
[SID160689029]
[CID15951642]
IC50 3.5Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
14
[SID160688738]
[CID70689750]
IC50 3.7Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
15
[SID160678047]
[CID70685558]
IC50 3.9Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
16
[SID160699591]
[CID70693954]
IC50 4.1Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
17
[SID160704909]
[CID70696068]
IC50 4.7Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
18
[SID160699587]
[CID70693950]
IC50 5.1Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
19
[SID160672738]
[CID70683455]
IC50 6.7Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
20
[SID160678046]
[CID70685557]
IC50 6.8Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
21
[SID160694238]
[CID70691901]
IC50 7.5Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
22
[SID160704910]
[CID70696069]
IC50 8.1Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
23
[SID160672737]
[CID70683454]
IC50 9.4Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
24
[SID160699589]
[CID70693952]
IC50 10.3Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
25
[SID160694239]
[CID70691902]
IC50 12Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
26
[SID160667651]
[CID70681470]
IC50 14Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
27
[SID160683403]
[CID70687705]
IC50 14.6Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
28
[SID160694240]
[CID70691903]
IC50 17.5Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
29
[SID160678048]
[CID70685559]
IC50 19.9Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
30
[SID160683404]
[CID70687706]
IC50 20Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
31
[SID160694243]
[CID70691905]
IC50 42Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique [AID659183, Type: Literature]
View
32
[SID164137747]
[CID71655266]
Inhibition of mouse FAP expressed in human HEK293 cells using N-terminal blocked Z-GP-AMC substrate at 0.036 uM to 1 uM preincubated for 10 mins prior to substrate addition by fluorescence assay in presence of prolyl endopeptidase [AID736676, Type: Literature]
View
33
[SID103680228]
[CID45266496]
Binding affinity to mouse FAP assessed as enzyme mediated drug cleavage by measuring Pyro fluorescence [AID347011, Type: Literature]
View
34
[SID103680228]
[CID45266496]
Activity of mouse FAP expressed in HEK293 cells assessed as enzyme-mediated drug activation by measuring intracellular fluorescence after 6 hrs by confocal microscopy [AID346998, Type: Literature]
View