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tyrosine-protein kinase Yes [Homo sapiens] [gi:4885661] - Target BioActivity Data
Filters: All Data » Active      
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BioActivity Outcomes:
Active(502)
 
 
BioAssay Types:
Literature(483)
 
 
Confirmatory(18)
 
 
BioActivity Types:
Potency(378)
 
 
Kd(67)
 
 
IC50(47)
 
 
Ki(1)
 
 
Substance Types:
Chemical(502)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 22    Data Row: 502   Total Pages: 26   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID137275855]
[CID5311382]
Potency 9.72e-06qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]
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2
[SID124898784]
[CID24821094]
Potency 5e-05qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]
View
3
[SID137275915]
[CID57519527]
Potency 0.0002qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]
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4
[SID137275996]
[CID24826799]
Potency 0.0002qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]
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5
[SID137276000]
[CID56965894]
Potency 0.0002qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]
View
6
[SID99460834]
[CID25256849]
Potency 0.0002qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]
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7
[SID103501621]
[CID3062316]
Kd 0.0003Binding constant for YES kinase domain [AID435328, Type: Literature]
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8
[SID103501621]
[CID3062316]
Kd 0.0003Binding constant for YES kinase domain [AID625018, Type: Literature]
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9
[SID137275855]
[CID5311382]
Potency 0.0004qHTS for small molecule inhibitors of Yes1 kinase: Confirmatory screen on the cherrypicks [AID686948, Type: confirmatory]
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10
[SID137275842]
[CID10302451]
Potency 0.0004qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]
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11
[SID103501621]
[CID3062316]
IC50 0.0005Inhibition of Yes [AID271968, Type: Literature]
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12
[SID103501621]
[CID3062316]
IC50 0.0005Inhibition of yes kinase [AID282232, Type: Literature]
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13
[SID103501621]
[CID3062316]
IC50 0.0005Inhibition of Yes1 (unknown origin) assessed as kinase-dependent enzymatic production of ADP from ATP using coupled luminescence-based reaction by ADP-Glo kinase assay [AID761478, Type: Literature]
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14
[SID137276050]
[CID16086114]
Potency 0.0007qHTS for small molecule inhibitors of Yes1 kinase: Confirmatory screen on the cherrypicks [AID686948, Type: confirmatory]
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15
[SID103501598]
[CID10302451]
IC50 0.0007Inhibition of Yes1 (unknown origin) by [gamma-33P]-ATP radiolabeled enzyme activity assay [AID761477, Type: Literature]
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16
[SID103501621]
[CID3062316]
IC50 0.001Inhibition of Yes1 (unknown origin) by [gamma-33P]-ATP radiolabeled enzyme activity assay [AID761477, Type: Literature]
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17
[SID103506891]
[CID11719421]
IC50 0.001Inhibition of Yes [AID276183, Type: Literature]
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18
[SID103551373]
[CID25138012]
Kd 0.001Binding affinity to human YES [AID389065, Type: Literature]
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19
[SID103628628]
[CID9977819]
IC50 0.0014Inhibition of Yes1 (unknown origin) by [gamma-33P]-ATP radiolabeled enzyme activity assay [AID761477, Type: Literature]
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20
[SID124958086]
[CID25066467]
IC50 0.0015Inhibition of Yes1 (unknown origin) by [gamma-33P]-ATP radiolabeled enzyme activity assay [AID761477, Type: Literature]
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