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BioActivity Data for Targets
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BioActivity Outcomes:
Active(80)
 
 
BioAssay Types:
Literature(80)
 
 
BioActivity Types:
IC50(10)
 
 
Substance Types:
Chemical(80)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 16    Data Row: 80   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103769200]
[CID46898044]
IC50 1.6Inhibition of human Gli1 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter gene assay [AID491223, Type: Literature]
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2
[SID103768592]
[CID46898040]
IC50 2.6Inhibition of human Gli1 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter gene assay [AID491223, Type: Literature]
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3
[SID103685698]
[CID44190252]
IC50 6.9Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase reporter gene assay [AID421257, Type: Literature]
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4
[SID103689210]
[CID44189870]
IC50 9.4Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase reporter gene assay [AID421257, Type: Literature]
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5
[SID103680450]
[CID44190064]
IC50 11.4Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase reporter gene assay [AID421257, Type: Literature]
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6
[SID103683909]
[CID45268743]
IC50 11.4Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase reporter gene assay [AID421257, Type: Literature]
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7
[SID103165295]
[CID64971]
IC50 32Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assay [AID389502, Type: Literature]
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8
[SID103595259]
[CID21672700]
IC50 38Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assay [AID389502, Type: Literature]
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9
[SID103596136]
[CID421610]
IC50 40Inhibition of human Gli1-mediated transcriptional activity in human Rh30 cells after 24 hrs by luciferase reporter gene assay [AID491229, Type: Literature]
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10
[SID103595322]
[CID12305768]
IC50 42Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assay [AID389502, Type: Literature]
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11
[SID103596136]
[CID421610]
Reduction of GLI1 mediated transcription in HEK293 cells by luciferase reporter assay [AID358315, Type: Literature]
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12
[SID103595259]
[CID21672700]
Effect on Hh/GLI-mediated transcription in human PANC1 assessed as decrease in PCTH protein expression by Western blot [AID389509, Type: Literature]
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13
[SID103595259]
[CID21672700]
Effect on Hh/GLI-mediated transcription in human PANC1 assessed as decrease in BCL2 protein expression by Western blot [AID389510, Type: Literature]
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14
[SID103165295]
[CID64971]
Effect on Hh/GLI-mediated transcription in human HaCaT cells assessed as reduction of PTCH protein expression by Western blot [AID389506, Type: Literature]
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15
[SID103165295]
[CID64971]
Effect on Hh/GLI-mediated transcription in human HaCaT cells assessed as reduction of BCL2 protein expression by Western blot [AID389507, Type: Literature]
View
16
[SID103165295]
[CID64971]
Effect on Hh/GLI-mediated transcription in human PANC1 assessed as decrease in PCTH protein expression by Western blot [AID389509, Type: Literature]
View
17
[SID103165295]
[CID64971]
Effect on Hh/GLI-mediated transcription in human PANC1 assessed as decrease in BCL2 protein expression by Western blot [AID389510, Type: Literature]
View
18
[SID103595203]
[CID253078]
Reduction of GLI1 mediated transcription in HEK293 cells by luciferase reporter assay [AID358315, Type: Literature]
View
19
[SID103683918]
[CID836999]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
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20
[SID103683918]
[CID836999]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
21
[SID103685675]
[CID45269605]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
22
[SID103685675]
[CID45269605]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
23
[SID103685676]
[CID45269606]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
24
[SID103685676]
[CID45269606]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
25
[SID103685686]
[CID45269611]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
26
[SID103685686]
[CID45269611]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
27
[SID103680450]
[CID44190064]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
28
[SID103680450]
[CID44190064]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
29
[SID103680450]
[CID44190064]
Inhibition of endogenously overexpressed Gli1-mediated transcriptional activity in human Rh30 cells at 10 uM after 24 hrs by luciferase reporter gene assay [AID421282, Type: Literature]
View
30
[SID103680450]
[CID44190064]
Inhibition of endogenously overexpressed Gli1-mediated transcriptional activity in human Rh30 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421283, Type: Literature]
View
31
[SID103680450]
[CID44190064]
Inhibition of endogenously overexpressed Gli1-mediated transcriptional activity in human Rh30 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421284, Type: Literature]
View
32
[SID103680475]
[CID45267048]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
33
[SID103680475]
[CID45267048]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
34
[SID103680486]
[CID44189776]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
35
[SID103680486]
[CID44189776]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
36
[SID103680493]
[CID44189868]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
37
[SID103680493]
[CID44189868]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
38
[SID103680494]
[CID44190251]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
39
[SID103680494]
[CID44190251]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
40
[SID103680504]
[CID44189869]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
41
[SID103680504]
[CID44189869]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
42
[SID103682204]
[CID44189962]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
43
[SID103682204]
[CID44189962]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
44
[SID103680448]
[CID45266983]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
45
[SID103680448]
[CID45266983]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
46
[SID103680449]
[CID44191205]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
47
[SID103680449]
[CID44191205]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
48
[SID103689210]
[CID44189870]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View
49
[SID103689210]
[CID44189870]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 40 uM after 24 hrs by luciferase reporter gene assay [AID421259, Type: Literature]
View
50
[SID103690943]
[CID44190159]
Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay [AID421258, Type: Literature]
View