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3-phosphoinositide-dependent protein kinase 1.. [gi:4505695] - Target BioActivity Data
Also known as: 3-phosphoinositide-dependent protein kinase 1 isoform 1 [Homo sapiens].
Filters: All Data » Active      
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BioActivity Outcomes:
Active(168)
 
 
BioAssay Types:
Literature(161)
 
 
Confirmatory(7)
 
 
BioActivity Types:
IC50(137)
 
 
Kd(17)
 
 
AC50(2)
 
 
Substance Types:
Chemical(168)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 34    Data Row: 168   Total Pages: 9   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103243222]
[CID44299148]
Kd 0.0017Binding constant for full-length PDPK1 [AID435189, Type: Literature]
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2
[SID103243222]
[CID44299148]
Kd 0.0017Binding constant for PDPK1 kinase domain [AID624876, Type: Literature]
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3
[SID163339605]
[CID10347359]
IC50 0.0023Displacement of [gamma33P]ATP from human TBK1 expressed in insect sf21 cells measured for 30 mins [AID729483, Type: Literature]
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4
[SID103536234]
[CID11738018]
IC50 0.003Inhibition of PDK1 mediated cAKT2 phosphorylation by AKT2 activation assay [AID299513, Type: Literature]
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5
[SID103749805]
[CID25060409]
IC50 0.003Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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6
[SID103749823]
[CID46192858]
IC50 0.003Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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7
[SID103749845]
[CID46192989]
IC50 0.003Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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8
[SID164133368]
[CID71717270]
Kd 0.0034Binding constant for PDPK1 kinase domain [AID624876, Type: Literature]
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9
[SID103749803]
[CID46192856]
IC50 0.005Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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10
[SID103524347]
[CID11161844]
IC50 0.005Inhibition of PDK1 mediated cAKT2 phosphorylation by AKT2 activation assay [AID299513, Type: Literature]
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11
[SID103524347]
[CID11161844]
IC50 0.006Inhibition of PDK1 (unknown origin) [AID729480, Type: Literature]
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12
[SID103749804]
[CID25060410]
IC50 0.006Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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13
[SID103749806]
[CID46192857]
IC50 0.006Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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14
[SID103749869]
[CID46193129]
IC50 0.006Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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15
[SID103749936]
[CID46193132]
IC50 0.006Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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16
[SID103749894]
[CID46193131]
IC50 0.008Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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17
[SID103749895]
[CID25060411]
IC50 0.008Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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18
[SID103749826]
[CID44608012]
IC50 0.008Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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19
[SID103749937]
[CID46193133]
IC50 0.009Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells [AID477040, Type: Literature]
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20
[SID131274687]
[CID54581311]
IC50 0.009Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISA [AID592183, Type: Literature]
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