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hypoxia-inducible factor 1-alpha isoform 1 [H.. [gi:4504385] - Target BioActivity Data
Also known as: hypoxia-inducible factor 1-alpha isoform 1 [Homo sapiens].
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BioActivity Outcomes:
Active(2431)
 
 
BioAssay Types:
Screening(1262)
 
 
Confirmatory(879)
 
 
Literature(290)
 
 
BioActivity Types:
Potency(685)
 
 
IC50(347)
 
 
EC50(72)
 
 
Ki(7)
 
 
Substance Types:
Chemical(2431)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 56    Data Row: 2431   Total Pages: 122   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID134459781]
[CID53248886]
IC50 0.001Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay [AID603554, Type: Literature]
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2
[SID855515]
[CID443958]
Potency 0.0013qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
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3
[SID11110860]
[CID11972586]
Potency 0.0016qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
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4
[SID11112841]
[CID11972600]
Potency 0.0025qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
5
[SID163322205]
[CID59504627]
IC50 0.003Inhibition of HIF-1alpha in human HCT116 cells under hypoxia condition by HRE-luciferase reporter gene assay [AID714182, Type: Literature]
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6
[SID134459779]
[CID53306270]
IC50 0.0042Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay [AID603554, Type: Literature]
View
7
[SID855924]
[CID5311067]
Potency 0.005qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
8
[SID11110856]
[CID6603742]
Potency 0.0063qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
9
[SID134444378]
[CID42604718]
IC50 0.00676Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay [AID603554, Type: Literature]
View
10
[SID103481840]
[CID14539883]
IC50 0.00676Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay [AID603554, Type: Literature]
View
11
[SID134448296]
[CID53306435]
IC50 0.007Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay [AID603554, Type: Literature]
View
12
[SID26751135]
[CID16758549]
Potency 0.0079qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
13
[SID855773]
[CID236702]
Potency 0.0079qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
14
[SID4253755]
[CID3246454]
Potency 0.01qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
15
[SID134436661]
[CID53306268]
IC50 0.01Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay [AID603554, Type: Literature]
View
16
[SID103684211]
[CID25208124]
IC50 0.0107Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assay [AID603554, Type: Literature]
View
17
[SID4254404]
[CID461805]
Potency 0.0126qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
18
[SID164134339]
[CID71625259]
IC50 0.014Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc after 12 hrs by luciferase reporter gene assay [AID726052, Type: Literature]
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19
[SID4254426]
[CID3246735]
Potency 0.0158qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View
20
[SID4254063]
[CID3246585]
Potency 0.0158qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]
View