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thyroid hormone receptor beta [Homo sapiens] [gi:40806162] - Target BioActivity Data
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BioActivity Outcomes:
Probe(1)
 
 
Active(1676)
 
 
BioAssay Types:
Confirmatory(1180)
 
 
Literature(482)
 
 
Summary(6)
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(1186)
 
 
 
IC50(349)
 
 
Ki(64)
 
 
EC50(31)
 
 
Kd(25)
 
 
Substance Types:
Chemical(1677)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 55    Data Row: 1677   Total Pages: 34   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID87550851]
[CID5184800]
Tx-SRC2-2 Potency (uM) 1.4qHTS Assay for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2: Probe Summary [AID2512, Type: summary]
View
2
[SID103219193]
[CID5804]
IC50 1.91e-05Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
3
[SID103219195]
[CID10456830]
IC50 2.51e-05Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
4
[SID103219116]
[CID5803]
IC50 4.79e-05Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
5
[SID103356078]
[CID22339645]
IC50 5.62e-05Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
6
[SID24275635]
[CID15991372]
Potency 5.623e-05Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
7
[SID103481478]
[CID9951790]
IC50 6e-05Inhibition of human TR-beta-1 by radioligand binding assay [AID261713, Type: Literature]
View
8
[SID103570000]
[CID5920]
Kd 8.1e-05Displacement of [125I]T3 from human TRbeta receptor [AID323175, Type: Literature]
View
9
[SID103218344]
[CID9933119]
IC50 9.5e-05Binding affinity at human thyroid hormone receptor beta-1 expressed in CHOK1 cells [AID299561, Type: Literature]
View
10
[SID103218344]
[CID9933119]
IC50 9.55e-05Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
11
[SID103327605]
[CID9862248]
Kd 0.0001Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3 [AID213183, Type: Literature]
View
12
[SID103570000]
[CID5920]
Kd 0.0001Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3 [AID213183, Type: Literature]
View
13
[SID103538695]
[CID6431911]
IC50 0.00011Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
14
[SID103356191]
[CID22339458]
IC50 0.000112Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
15
[SID103570000]
[CID5920]
Kd 0.00014Binding affinity towards thyroid hormone receptor (hTR beta 1) [AID213176, Type: Literature]
View
16
[SID103219085]
[CID10904700]
IC50 0.000151Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
17
[SID103355713]
[CID10390904]
IC50 0.000195Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
18
[SID103327605]
[CID9862248]
Kd 0.0002Binding affinity to human TRbeta1 [AID715452, Type: Literature]
View
19
[SID24407537]
[CID7522100]
Potency 0.0002Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
20
[SID103218312]
[CID9863447]
Ki 0.00024Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assay [AID345696, Type: Literature]
View
21
[SID103570000]
[CID5920]
IC50 0.000257Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
22
[SID103570000]
[CID5920]
IC50 0.00026Inhibitory concentration against cloned human thyroid hormone receptor beta 1 [AID254845, Type: Literature]
View
23
[SID103570000]
[CID5920]
IC50 0.00026Binding affinity at human thyroid hormone receptor beta-1 expressed in CHOK1 cells [AID299561, Type: Literature]
View
24
[SID103178526]
[CID71212]
IC50 0.00026Inhibition of human TR-beta-1 by radioligand binding assay [AID261713, Type: Literature]
View
25
[SID103536318]
[CID23648083]
IC50 0.00027Binding affinity at human thyroid hormone receptor beta-1 expressed in CHOK1 cells [AID299561, Type: Literature]
View
26
[SID103481449]
[CID10479779]
IC50 0.00028Inhibition of human TR-beta-1 by radioligand binding assay [AID261713, Type: Literature]
View
27
[SID103356448]
[CID22339386]
IC50 0.000282Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
28
[SID103469103]
[CID10456672]
IC50 0.0003Inhibitory concentration against cloned human thyroid hormone receptor beta 1 [AID254845, Type: Literature]
View
29
[SID103469110]
[CID10479778]
IC50 0.0003Inhibitory concentration against cloned human thyroid hormone receptor beta 1 [AID254845, Type: Literature]
View
30
[SID103469127]
[CID44403634]
IC50 0.0003Inhibitory concentration against cloned human thyroid hormone receptor beta 1 [AID254845, Type: Literature]
View
31
[SID17513059]
[CID5928009]
Potency 0.0003Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
32
[SID17515268]
[CID2137859]
Potency 0.0003Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
33
[SID103327605]
[CID9862248]
Ki 0.00032Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assay [AID345696, Type: Literature]
View
34
[SID103356391]
[CID22339633]
IC50 0.000363Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
35
[SID17516151]
[CID4876898]
Potency 0.0004Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
36
[SID24275651]
[CID5769582]
Potency 0.0004Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
37
[SID24407569]
[CID16028928]
Potency 0.0004Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
38
[SID160695033]
[CID10299876]
Ki 0.00043Displacement of [125I]T3 from human recombinant thyroid harmone receptor beta after 16 to 48 hrs by gamma-ray detection [AID664440, Type: Literature]
View
39
[SID103538804]
[CID23648136]
IC50 0.000468Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
40
[SID103225357]
[CID9874938]
Ki 0.00047Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assay [AID345696, Type: Literature]
View
41
[SID24404675]
[CID16026224]
Potency 0.0005Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
42
[SID24410465]
[CID16031499]
Potency 0.0005Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
43
[SID103335044]
[CID10413582]
Kd 0.00052Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3 [AID213183, Type: Literature]
View
44
[SID103536321]
[CID23648086]
IC50 0.0006Binding affinity at human thyroid hormone receptor beta-1 expressed in CHOK1 cells [AID299561, Type: Literature]
View
45
[SID24389952]
[CID16013108]
Potency 0.0006Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
46
[SID17508059]
[CID2979650]
Potency 0.0006Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View
47
[SID103538795]
[CID656928]
IC50 0.000617Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
48
[SID103538715]
[CID22339678]
IC50 0.000646Inhibition of human thyroid hormone receptor beta 1 [AID299948, Type: Literature]
View
49
[SID103570000]
[CID5920]
Ki 0.00068Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assay [AID345696, Type: Literature]
View
50
[SID24396336]
[CID16018389]
Potency 0.0007Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]
View