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serine/threonine-protein kinase B-raf [Homo s.. [gi:33188459] - Target BioActivity Data
Also known as: serine/threonine-protein kinase B-raf [Homo sapiens].
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BioActivity Outcomes:
Active(405)
 
 
BioAssay Types:
Literature(401)
 
 
BioActivity Types:
IC50(303)
 
 
Kd(87)
 
 
EC50(3)
 
 
Ki(1)
 
 
Substance Types:
Chemical(405)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 41    Data Row: 405   Total Pages: 9   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103642962]
[CID11616462]
IC50 2e-05Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
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2
[SID103643282]
[CID11653652]
IC50 3e-05Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
3
[SID103643051]
[CID44587047]
IC50 4e-05Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
4
[SID103643223]
[CID44587190]
IC50 5e-05Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
5
[SID103643052]
[CID44587048]
IC50 9e-05Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
6
[SID103643222]
[CID11717001]
IC50 0.00013Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
7
[SID103642961]
[CID11522118]
IC50 0.00015Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
8
[SID103623690]
[CID11316960]
Ki 0.00016Inhibition of N-terminus His-6 tagged human B-Raf expressed in baculovirus infected insect Sf9 cells [AID644002, Type: Literature]
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9
[SID103476069]
[CID11316960]
Kd 0.00016Binding affinity to human N-His6-tagged B-Raf expressed in Sf9 cells [AID632312, Type: Literature]
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10
[SID103643222]
[CID11717001]
Kd 0.00018Binding constant for BRAF(V600E) kinase domain [AID624947, Type: Literature]
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11
[SID103643222]
[CID11717001]
Kd 0.00019Binding constant for BRAF kinase domain [AID624946, Type: Literature]
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12
[SID103643341]
[CID11624965]
IC50 0.00022Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
13
[SID103643343]
[CID44587235]
IC50 0.00023Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
14
[SID103623690]
[CID11316960]
Kd 0.0003Binding affinity at bRaf kinase in fluorescent ligand displacement assay [AID258282, Type: Literature]
View
15
[SID103737886]
[CID44226449]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
16
[SID103738109]
[CID46880076]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
17
[SID103738155]
[CID46880102]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
18
[SID103738156]
[CID46880103]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
19
[SID103738157]
[CID46880104]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
20
[SID103738216]
[CID46880137]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
21
[SID103738217]
[CID46880138]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
22
[SID103738310]
[CID46198375]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
23
[SID103738311]
[CID46880217]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
24
[SID103738312]
[CID46880218]
IC50 0.00032Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
25
[SID103643050]
[CID11545261]
IC50 0.00033Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
26
[SID103643283]
[CID11639637]
IC50 0.00034Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
27
[SID103738215]
[CID46880136]
IC50 0.00038Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
28
[SID103643280]
[CID11660270]
IC50 0.00039Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
29
[SID103737152]
[CID46879452]
IC50 0.00044Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
30
[SID103643281]
[CID44587211]
IC50 0.00047Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
31
[SID103642963]
[CID11536794]
IC50 0.00048Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
32
[SID103738108]
[CID46880075]
IC50 0.00049Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
33
[SID103737150]
[CID46879450]
IC50 0.0005Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
34
[SID103737149]
[CID46879449]
IC50 0.00051Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
35
[SID103643225]
[CID44587191]
IC50 0.00056Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
36
[SID103642964]
[CID44586991]
IC50 0.00057Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
37
[SID103643342]
[CID44587234]
IC50 0.00085Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
38
[SID103643224]
[CID11566757]
IC50 0.00087Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
39
[SID103737884]
[CID44226447]
IC50 0.0009Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
40
[SID103737238]
[CID46879520]
IC50 0.001Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
41
[SID103738107]
[CID46880074]
IC50 0.001Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
42
[SID104240101]
[CID46919121]
IC50 0.001Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assay [AID497610, Type: Literature]
View
43
[SID103643053]
[CID44587049]
IC50 0.00116Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
44
[SID103643340]
[CID11610758]
IC50 0.0012Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
45
[SID103476060]
[CID17950751]
Kd 0.0013Binding affinity at bRaf kinase in fluorescent ligand displacement assay [AID258282, Type: Literature]
View
46
[SID103643543]
[CID25093326]
IC50 0.0015Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View
47
[SID103738017]
[CID46880015]
IC50 0.0015Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
48
[SID103700624]
[CID45484011]
IC50 0.0018Inhibition of Braf in human A375 cells assessed as inhibition of ERK phosphorylation [AID438980, Type: Literature]
View
49
[SID103738016]
[CID46880014]
IC50 0.002Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylation [AID469343, Type: Literature]
View
50
[SID103643474]
[CID11500476]
IC50 0.002Inhibition of human recombinant B-Raf by fluorescence anisotropy [AID362268, Type: Literature]
View