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peroxisome proliferator-activated receptor ga.. [gi:20336229] - Target BioActivity Data
Also known as: peroxisome proliferator-activated receptor gamma isoform 2 [Homo sapiens].
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BioActivity Outcomes:
Probe(1)
 
 
Active(8046)
 
 
BioAssay Types:
Literature(3049)
 
 
Screening(3040)
 
 
Confirmatory(428)
 
 
BioActivity Types:
EC50(2032)
 
 
IC50(996)
 
 
Ki(153)
 
 
Kd(15)
 
 
Substance Types:
Chemical(8047)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 319    Data Row: 8047   Total Pages: 161   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID124349301]
[CID53239856]
Late stage assay provider counterscreen results from the probe development effort to identify non-agonists of the peroxisome proliferator-activated receptor gamma (PPARg): chemiluminescence-based biochemical western blot assay for inhibitors of phosphorylation of PPARG protein levels [AID504938, Type: other]
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2
[SID134447814]
[CID56669690]
EC50 1e-07Transactivation of human PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610311, Type: Literature]
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3
[SID134436215]
[CID56659348]
EC50 2e-07Transactivation of human PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610311, Type: Literature]
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4
[SID134459372]
[CID56679849]
EC50 3e-07Transactivation of human PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610311, Type: Literature]
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5
[SID134436214]
[CID56659347]
EC50 1.5e-06Transactivation of human PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610311, Type: Literature]
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6
[SID134455510]
[CID53233135]
EC50 1.8e-05Transactivation of human PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610311, Type: Literature]
View
7
[SID134447813]
[CID56669689]
EC50 5e-05Transactivation of human PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610311, Type: Literature]
View
8
[SID103521630]
[CID25263407]
EC50 0.0001Agonist activity at human PPARgamma in HepG2 cells by PPAR-GAL4 transactivation assay [AID289933, Type: Literature]
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9
[SID103521626]
[CID25263404]
EC50 0.00019Agonist activity at human PPARgamma in HepG2 cells by PPAR-GAL4 transactivation assay [AID289933, Type: Literature]
View
10
[SID103453949]
[CID446642]
EC50 0.0002Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assay [AID240313, Type: Literature]
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11
[SID103569797]
[CID446642]
EC50 0.00028Agonist activity at human PPARgamma [AID330492, Type: Literature]
View
12
[SID103521625]
[CID25263403]
EC50 0.0003Agonist activity at human PPARgamma in HepG2 cells by PPAR-GAL4 transactivation assay [AID289933, Type: Literature]
View
13
[SID103521628]
[CID25263406]
EC50 0.00031Agonist activity at human PPARgamma in HepG2 cells by PPAR-GAL4 transactivation assay [AID289933, Type: Literature]
View
14
[SID103324541]
[CID170364]
EC50 0.00034Agonist activity for Human PPAR gamma receptor in transcriptional activation assay [AID91246, Type: Literature]
View
15
[SID103521627]
[CID25263405]
EC50 0.00036Agonist activity at human PPARgamma in HepG2 cells by PPAR-GAL4 transactivation assay [AID289933, Type: Literature]
View
16
[SID124349300]
IC50 0.00037Late stage assay provider results from the probe development effort to identify non-agonists of the peroxisome proliferator-activated receptor gamma (PPARg): TR-FRET-based biochemical dose response competitive binding lanthascreen assay for non-agonists of the PPARg [AID504943, Type: confirmatory]
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17
[SID103261196]
[CID18944089]
Ki 0.0004inhibition of [125I]SB 236636 binding to human PPAR gamma receptor [AID156385, Type: other]
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18
[SID103316922]
[CID44331685]
EC50 0.0005Agonistic transcriptional activity in CV-1 cells expressing Gal4-PPAR gamma chimera [AID156798, Type: Literature]
View
19
[SID104223102]
EC50 0.0005Late stage assay provider results from the probe development effort to identify non-agonists of the peroxisome proliferator-activated receptor gamma (PPARg): Luminescence-based cell-based dose response assay to identify transactivation inhibitor of PPRE (PPARG response element) [AID504939, Type: confirmatory]
View
20
[SID134435271]
[CID44132339]
EC50 0.000501Partial agonist activity at human PPARgamma by luciferase reporter gene assay [AID617443, Type: Literature]
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21
[SID134461452]
[CID44132175]
EC50 0.000501Partial agonist activity at human PPARgamma by luciferase reporter gene assay [AID617443, Type: Literature]
View
22
[SID103521658]
[CID25263408]
EC50 0.00054Agonist activity at human PPARgamma in HepG2 cells by PPAR-GAL4 transactivation assay [AID289933, Type: Literature]
View
23
[SID104223102]
IC50 0.00054Late stage assay provider results from the probe development effort to identify non-agonists of the peroxisome proliferator-activated receptor gamma (PPARg): TR-FRET-based biochemical dose response competitive binding lanthascreen assay for non-agonists of the PPARg [AID504943, Type: confirmatory]
View
24
[SID124349300]
EC50 0.00054Late stage assay provider results from the probe development effort to identify non-agonists of the peroxisome proliferator-activated receptor gamma (PPARg): Luminescence-based cell-based dose response assay to identify transactivation inhibitor of PPRE (PPARG response element) [AID504939, Type: confirmatory]
View
25
[SID103521624]
[CID11751301]
EC50 0.00055Agonist activity at human PPARgamma in HepG2 cells by PPAR-GAL4 transactivation assay [AID289933, Type: Literature]
View
26
[SID103324541]
[CID170364]
EC50 0.0006Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assay [AID306521, Type: Literature]
View
27
[SID134459373]
[CID56679850]
EC50 0.0006Transactivation of human PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-Luc by luciferase reporter gene assay [AID610311, Type: Literature]
View
28
[SID103324548]
[CID9870584]
EC50 0.00071Agonist activity for Human PPAR gamma receptor in transcriptional activation assay [AID91246, Type: Literature]
View
29
[SID103486120]
[CID2742759]
EC50 0.00078Effect on Gal4/PPAR-gamma-LBD construct transactivation in Huh7 cells [AID264336, Type: Literature]
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30
[SID134446057]
[CID44132174]
EC50 0.000794Partial agonist activity at human PPARgamma by luciferase reporter gene assay [AID617443, Type: Literature]
View
31
[SID103728922]
[CID46233002]
EC50 0.0008Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay [AID459526, Type: Literature]
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32
[SID160690077]
[CID16064276]
EC50 0.00094Modulation of full-length human pSG5-fused PPARgamma expressed in MG-63 cells co-expressing pGV-P2-PPRE after 24 hrs by luciferase reporter gene based transactivation assay [AID666690, Type: Literature]
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33
[SID136941043]
[CID9845965]
EC50 0.001Partial agonist activity at human PPARgamma LBD assessed as activation of PBP by HTRF assay [AID643841, Type: Literature]
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34
[SID136941043]
[CID9845965]
EC50 0.001Partial agonist activity at human PPARgamma LBD assessed as activation of CBP1-453 by HTRF assay [AID643835, Type: Literature]
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35
[SID136941043]
[CID9845965]
EC50 0.001Partial agonist activity at human PPARgamma LBD assessed as activation of PGC1 by HTRF assay [AID643837, Type: Literature]
View
36
[SID103728989]
[CID46233039]
EC50 0.001Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay [AID459526, Type: Literature]
View
37
[SID103651812]
[CID44591474]
IC50 0.001Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from GST-fused human PPARgamma expressed in Escherichia coli BL21 cells by scintillation proximity assay [AID354041, Type: Literature]
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38
[SID103683985]
[CID44190764]
EC50 0.001Agonist activity at human PPARgamma receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation assay [AID421049, Type: Literature]
View
39
[SID103690975]
[CID45272171]
IC50 0.001Inhibition of human PPARgamma receptor by scintillation proximity assay [AID421047, Type: Literature]
View
40
[SID103586566]
[CID44190592]
IC50 0.001Displacement of [3H]2AD-5075 from GST-tagged human PPARgamma receptor expressed in Escherichia coli BL21 [AID364412, Type: Literature]
View
41
[SID103586566]
[CID44190592]
EC50 0.001Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assay [AID364413, Type: Literature]
View
42
[SID103586566]
[CID44190592]
IC50 0.001Inhibition of human PPARgamma receptor by scintillation proximity assay [AID421047, Type: Literature]
View
43
[SID103586566]
[CID44190592]
EC50 0.001Agonist activity at human PPARgamma receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation assay [AID421049, Type: Literature]
View
44
[SID103586783]
[CID25164959]
EC50 0.001Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assay [AID364413, Type: Literature]
View
45
[SID103586784]
[CID25164960]
IC50 0.001Displacement of [3H]2AD-5075 from GST-tagged human PPARgamma receptor expressed in Escherichia coli BL21 [AID364412, Type: Literature]
View
46
[SID103586784]
[CID25164960]
EC50 0.001Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assay [AID364413, Type: Literature]
View
47
[SID103586786]
[CID25165359]
IC50 0.001Displacement of [3H]2AD-5075 from GST-tagged human PPARgamma receptor expressed in Escherichia coli BL21 [AID364412, Type: Literature]
View
48
[SID103586786]
[CID25165359]
EC50 0.001Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assay [AID364413, Type: Literature]
View
49
[SID103630491]
[CID25147933]
EC50 0.001Agonist activity at human PPARgamma in U2OS cells by transactivation assay [AID396054, Type: Literature]
View
50
[SID103630492]
[CID25149129]
EC50 0.001Agonist activity at human PPARgamma in U2OS cells by transactivation assay [AID396054, Type: Literature]
View