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dual specificity mitogen-activated protein ki.. [gi:13489054] - Target BioActivity Data
Also known as: dual specificity mitogen-activated protein kinase kinase 2 [Homo sapiens].
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BioActivity Outcomes:
Active(75)
 
 
BioAssay Types:
Literature(74)
 
 
BioActivity Types:
Kd(43)
 
 
Ki(14)
 
 
IC50(2)
 
 
Substance Types:
Chemical(75)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 75   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID164133368]
[CID71717270]
Kd 0.0039Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
2
[SID103220856]
[CID5328940]
Kd 0.0099Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
3
[SID136938397]
[CID57399640]
Kd 0.013Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
4
[SID103441767]
[CID9915743]
Kd 0.026Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
5
[SID103243222]
[CID44299148]
Kd 0.028Binding constant for full-length MEK2 [AID435169, Type: Literature]
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6
[SID103243222]
[CID44299148]
Kd 0.028Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
7
[SID136935277]
[CID57397989]
Kd 0.042Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
8
[SID103175813]
[CID5329102]
Kd 0.11Binding constant for full-length MEK2 [AID435169, Type: Literature]
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9
[SID103175813]
[CID5329102]
Kd 0.11Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
10
[SID131277755]
[CID10138259]
Kd 0.12Binding constant for full-length MEK2 [AID435169, Type: Literature]
View
11
[SID131277755]
[CID10138259]
Kd 0.12Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
12
[SID123092542]
[CID24905147]
Kd 0.21Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
13
[SID103628628]
[CID9977819]
Kd 0.35Binding constant for full-length MEK2 [AID435169, Type: Literature]
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14
[SID103628628]
[CID9977819]
Kd 0.35Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
15
[SID103320975]
[CID6918454]
Kd 0.37Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
16
[SID136941612]
[CID44551653]
Kd 0.42Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
17
[SID124963590]
[CID10127622]
Kd 0.53Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
18
[SID103583785]
[CID16038120]
Kd 0.63Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
19
[SID103704523]
[CID45485677]
Ki 0.67Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
20
[SID103704453]
[CID45485625]
Ki 0.71Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
21
[SID103596121]
[CID11213558]
Kd 0.73Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
22
[SID103730344]
[CID6445562]
Kd 0.81Binding constant for full-length MEK2 [AID435169, Type: Literature]
View
23
[SID136944791]
[CID11427553]
Kd 0.85Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
24
[SID103583760]
[CID10461815]
Kd 0.98Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
25
[SID103194628]
[CID3081361]
Kd 1.1Binding constant for full-length MEK2 [AID435169, Type: Literature]
View
26
[SID103194628]
[CID3081361]
Kd 1.1Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
27
[SID104246213]
[CID24180719]
Kd 1.1Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
28
[SID103704480]
[CID45485645]
Ki 1.4Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
29
[SID103704533]
[CID45485687]
Ki 1.4Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
30
[SID103704505]
[CID45485664]
Ki 1.4Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
31
[SID103501621]
[CID3062316]
Kd 1.4Binding constant for full-length MEK2 [AID435169, Type: Literature]
View
32
[SID103501621]
[CID3062316]
Kd 1.4Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
33
[SID103202250]
[CID156414]
Kd 1.6Binding constant for full-length MEK2 [AID435169, Type: Literature]
View
34
[SID103202250]
[CID156414]
Kd 1.6Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
35
[SID103501621]
[CID3062316]
IC50 1.7Inhibition of MEK [AID282239, Type: Literature]
View
36
[SID103704506]
[CID45485665]
Ki 1.8Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
37
[SID103704481]
[CID45485646]
Ki 1.8Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
38
[SID103499403]
[CID447077]
Kd 1.9Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
39
[SID103573134]
[CID5494449]
Kd 2Binding constant for full-length MEK2 [AID435169, Type: Literature]
View
40
[SID103573134]
[CID5494449]
Kd 2Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
41
[SID103704507]
[CID45485666]
Ki 2.1Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
42
[SID103704474]
[CID45485640]
Ki 2.4Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
43
[SID123098392]
[CID6450551]
Kd 2.6Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
44
[SID136931825]
[CID9869779]
Kd 2.8Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
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45
[SID103592924]
[CID9933475]
Kd 3.1Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
46
[SID123089189]
[CID16722836]
Kd 3.1Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
47
[SID103704490]
[CID45485654]
Ki 3.7Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells [AID447515, Type: Literature]
View
48
[SID134449640]
[CID25126798]
Kd 4Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
49
[SID103502389]
[CID16007391]
Kd 4.2Binding constant for MEK2 kinase domain [AID625137, Type: Literature]
View
50
[SID103459325]
[CID5330790]
Kd 5.6Binding constant for full-length MEK2 [AID435169, Type: Literature]
View