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Interleukin-8; IL-8; C-X-C motif chemokine 8;.. [gi:124359] - Target BioActivity Data
Also known as: Interleukin-8; IL-8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor; MDNCF-a; GCP/IL-8 protein IV; IL8/NAP1 form I; Interleukin-8; (Ala-IL-8)77; GCP/IL-8 protein II; IL-8(1-77); IL8/NAP1 form II; MDNCF-b; IL-8(5-77); IL-8(6-77); (Ser-IL-8)72; GCP/IL-8 protein I; IL8/NAP1 form III; Lymphocyte-derived neutrophil-activating f.
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BioActivity Outcomes:
Active(228)
 
 
BioAssay Types:
Confirmatory(209)
 
 
Literature(19)
 
 
BioActivity Types:
IC50(187)
 
 
Potency(41)
 
 
Substance Types:
Chemical(228)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 228   Total Pages: 12   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103191369]
[CID3033]
IC50 0.008Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
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2
[SID103568331]
[CID18546352]
IC50 0.009Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
3
[SID103686313]
[CID45269905]
IC50 0.01Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
4
[SID103684529]
[CID45269050]
IC50 0.012Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
5
[SID103686293]
[CID45269894]
IC50 0.013Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
6
[SID103198657]
[CID13409348]
IC50 0.013Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
7
[SID103460096]
[CID180540]
IC50 0.02Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
8
[SID103688107]
[CID45270722]
IC50 0.02Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
9
[SID103277835]
[CID14076674]
IC50 0.025Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
10
[SID103691580]
[CID45272452]
IC50 0.025Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
11
[SID17389096]
[CID6167]
Potency 0.0473qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]
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12
[SID103459872]
[CID114864]
IC50 0.05Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
13
[SID103163840]
[CID3715]
IC50 0.05Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
14
[SID103686292]
[CID45269893]
IC50 0.05Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
15
[SID17389095]
[CID6167]
Potency 0.0531qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]
View
16
[SID103273527]
[CID5509]
IC50 0.09Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View
17
[SID144089017]
[CID4714904]
IC50_CF-PAF_Mean 0.228SAR analysis of molecule cystic fibrosis induced NFkb Inhibitors in a panel assay [AID651592_8, Type: confirmatory]
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18
[SID121286198]
[CID51361444]
IC50_Mean 0.293Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a PAF-induced IL8 counterscreen [AID624343, Type: confirmatory]
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19
[SID99358358]
[CID303610]
IC50_Mean 0.338Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a PAF-induced IL8 counterscreen [AID624343, Type: confirmatory]
View
20
[SID103277555]
[CID13752584]
IC50 0.4Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]
View