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Chir 99021 (CID 9956119) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(221)
 
 
Inactive(418)
 
 
Inconclusive(4)
 
 
Unspecified(573)
 
 
Top Targets:
PKc like(20)
 
 
 
PKc(7)
 
 
 
STKc AGC(4)
 
 
STKc JNK(3)
 
 
CYCLIN(2)
 
 
BioAssay Types:
Literature(217)
 
 
 
 
 
Confirmatory(18)
 
 
 
 
BioActivity Types:
IC50(673)
 
 
 
Potency(16)
 
 
 
 
AC50(3)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 777    Data Row: 1216   Total Pages: 25   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134216516]
AC50_uM 2.97e-06PathHunter bCatenin (U2-OS) Measured in Cell-Based System Using Plate Reader - 2133-06_Inhibitor_Dose_DryPowder_Activity [AID624088, Type: confirmatory]
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2
[SID134216516]
AC50_uM 0.002TCF/LEF Reporter Assay Measured in Cell-Based System Using Plate Reader - 2133-01_Inhibitor_Dose_DryPowder_Activity [AID624086, Type: confirmatory]
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3
[SID103566476]
IC50 0.007Inhibition of GSK3-beta [AID512484, Type: Literature]
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4
[SID103566476]
IC50 0.01Inhibition of GSK3alpha [AID512483, Type: Literature]
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5
[SID103566476]
IC50 0.03Inhibition of GSK3-beta [AID641178, Type: Literature]
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6
[SID103566476]
IC50 0.03Inhibition of human recombinant GSK3-beta after 1 hr by KinaseGlo luciferase assay [AID641179, Type: Literature]Glycogen synthase kinase-3 beta [gi:20455502]
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7
[SID103566476]
IC50 0.21416SANGER: Inhibition of human SW982 cell growth in a cell viability assay. [AID741919, Type: other]
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8
[SID103566476]
IC50 0.30672SANGER: Inhibition of human GCT cell growth in a cell viability assay. [AID742176, Type: other]
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9
[SID103566476]
IC50 0.58499SANGER: Inhibition of human 769-P cell growth in a cell viability assay. [AID741936, Type: other]
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10
[SID103566476]
IC50 0.58832SANGER: Inhibition of human LOXIMVI cell growth in a cell viability assay. [AID742321, Type: other]
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11
[SID103566476]
IC50 0.8462SANGER: Inhibition of human D-336MG cell growth in a cell viability assay. [AID742104, Type: other]
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12
[SID134216516]
AC50_uM 0.86Human p-Tau and Total Tau ELISA Measured in Cell-Based System Using Plate Reader - 2133-07_Inhibitor_Dose_DryPowder_Activity [AID624057, Type: confirmatory]
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13
[SID103566476]
IC50 0.92131SANGER: Inhibition of human S-117 cell growth in a cell viability assay. [AID741841, Type: other]
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14
[SID103566476]
IC50 0.94852SANGER: Inhibition of human D-247MG cell growth in a cell viability assay. [AID742101, Type: other]
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15
[SID103566476]
IC50 1.07912SANGER: Inhibition of human TYK-nu cell growth in a cell viability assay. [AID742028, Type: other]
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16
[SID103566476]
IC50 1.30469SANGER: Inhibition of human A498 cell growth in a cell viability assay. [AID741953, Type: other]
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17
[SID103566476]
EC50 1.5Inhibition of GSK3-beta in human HepG2 cells assessed as incorporation of [3H]glucose into glycogen after 3 hrs by liquid scintillation counting [AID641180, Type: Literature]Glycogen synthase kinase-3 beta [gi:20455502]
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18
[SID103566476]
IC50 1.66898SANGER: Inhibition of human BCPAP cell growth in a cell viability assay. [AID741974, Type: other]
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19
[SID103566476]
IC50 1.72788SANGER: Inhibition of human KYSE-180 cell growth in a cell viability assay. [AID742292, Type: other]
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20
[SID103566476]
IC50 1.75977SANGER: Inhibition of human MIA-PaCa-2 cell growth in a cell viability assay. [AID742363, Type: other]
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21
[SID103566476]
IC50 1.78273SANGER: Inhibition of human HCC1395 cell growth in a cell viability assay. [AID742192, Type: other]
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22
[SID103566476]
IC50 1.95415SANGER: Inhibition of human RS4-11 cell growth in a cell viability assay. [AID741834, Type: other]
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23
[SID103566476]
IC50 2.27684SANGER: Inhibition of human NCI-H2122 cell growth in a cell viability assay. [AID741728, Type: other]
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24
[SID103566476]
IC50 2.49787SANGER: Inhibition of human SNU-423 cell growth in a cell viability assay. [AID741889, Type: other]
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25
[SID103566476]
IC50 2.64128SANGER: Inhibition of human SK-LMS-1 cell growth in a cell viability assay. [AID741864, Type: other]
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26
[SID103566476]
IC50 2.70193SANGER: Inhibition of human RPMI-7951 cell growth in a cell viability assay. [AID741830, Type: other]
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27
[SID103566476]
IC50 2.7654SANGER: Inhibition of human COLO-829 cell growth in a cell viability assay. [AID742078, Type: other]
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28
[SID103566476]
IC50 2.95485SANGER: Inhibition of human SCC-9 cell growth in a cell viability assay. [AID741849, Type: other]
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29
[SID103566476]
IC50 3.0812SANGER: Inhibition of human A704 cell growth in a cell viability assay. [AID741956, Type: other]
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30
[SID103566476]
IC50 3.36054SANGER: Inhibition of human HOP-62 cell growth in a cell viability assay. [AID742219, Type: other]
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31
[SID103566476]
IC50 3.48305SANGER: Inhibition of human HCC1569 cell growth in a cell viability assay. [AID742194, Type: other]
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32
[SID103566476]
IC50 3.75498SANGER: Inhibition of human A172 cell growth in a cell viability assay. [AID741942, Type: other]
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33
[SID103566476]
IC50 3.88556SANGER: Inhibition of human MOLT-16 cell growth in a cell viability assay. [AID742373, Type: other]
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34
[SID103566476]
IC50 3.95343SANGER: Inhibition of human TE-15 cell growth in a cell viability assay. [AID742013, Type: other]
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35
[SID103566476]
IC50 3.96451SANGER: Inhibition of human OE19 cell growth in a cell viability assay. [AID741792, Type: other]
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36
[SID103566476]
IC50 4.04545SANGER: Inhibition of human MHH-ES-1 cell growth in a cell viability assay. [AID742360, Type: other]
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37
[SID103566476]
IC50 4.13971SANGER: Inhibition of human NKM-1 cell growth in a cell viability assay. [AID741780, Type: other]
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38
[SID103566476]
IC50 4.29479SANGER: Inhibition of human RCC10RGB cell growth in a cell viability assay. [AID741816, Type: other]
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39
[SID103566476]
IC50 4.70391SANGER: Inhibition of human BxPC-3 cell growth in a cell viability assay. [AID741990, Type: other]
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40
[SID103566476]
IC50 4.83858SANGER: Inhibition of human ALL-PO cell growth in a cell viability assay. [AID741961, Type: other]
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41
[SID103566476]
IC50 4.9934SANGER: Inhibition of human SK-OV-3 cell growth in a cell viability assay. [AID741880, Type: other]
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42
[SID103566476]
IC50 5.42456SANGER: Inhibition of human SW1710 cell growth in a cell viability assay. [AID741904, Type: other]
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43
[SID103566476]
IC50 5.45628SANGER: Inhibition of human NCI-H2452 cell growth in a cell viability assay. [AID741742, Type: other]
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44
[SID103566476]
IC50 5.49145SANGER: Inhibition of human D-392MG cell growth in a cell viability assay. [AID742105, Type: other]
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45
[SID103566476]
IC50 5.72627SANGER: Inhibition of human LB2518-MEL cell growth in a cell viability assay. [AID742306, Type: other]
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46
[SID103566476]
IC50 5.81266SANGER: Inhibition of human BL-41 cell growth in a cell viability assay. [AID741981, Type: other]
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47
[SID103566476]
IC50 5.81509SANGER: Inhibition of human WM-115 cell growth in a cell viability assay. [AID742045, Type: other]
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48
[SID103566476]
IC50 6.38344SANGER: Inhibition of human SK-MEL-2 cell growth in a cell viability assay. [AID741867, Type: other]
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49
[SID103566476]
IC50 6.417SANGER: Inhibition of human CGTH-W-1 cell growth in a cell viability assay. [AID742061, Type: other]
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50
[SID103566476]
IC50 6.53195SANGER: Inhibition of human BB65-RCC cell growth in a cell viability assay. [AID741971, Type: other]
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