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phenanthrene (CID 995) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(716)
 
 
Inconclusive(34)
 
 
Unspecified(26)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD AR(18)
 
 
 
NR LBD ER(18)
 
 
 
7TM GPCR Srx(14)
 
 
NR LBD TR(14)
 
 
 
BioAssay Types:
Confirmatory(401)
 
 
 
 
 
Screening(266)
 
 
Summary(48)
 
 
 
Literature(44)
 
 
 
 
BioActivity Types:
Potency(392)
 
 
 
 
 
IC50(11)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 603    Data Row: 782   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103225480]
IC50 26Inhibitory concentration against mouse cytochrome P450 2A5 [AID241174, Type: Literature]
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2
[SID103225480]
IC50 26.0016Inhibition of mouse CYP2A5 [AID420670, Type: Literature]Cytochrome P450 2A5 [gi:117196]
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3
[SID144210890]
Potency-Replicate_1 30.6379qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID144208836]
Potency-Replicate_1 59.4559qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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5
[SID144210890]
Potency-Replicate_1 68.5896qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID17388787]
Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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7
[SID103225480]
LC50 10Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay [AID762061, Type: Literature]
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8
[SID103225480]
LC50 10Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay [AID762062, Type: Literature]
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9
[SID103225480]
IC50 97Inhibitory concentration against human cytochrome P450 2A6 [AID241172, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
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10
[SID103225480]
IC50 97.051Inhibition of human CYP2A6 [AID420671, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
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11
[SID85272564]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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12
[SID103225480]
Antifungal activity against Microsporum canis C 112 by agar dilution method [AID376055, Type: Literature]
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13
[SID103225480]
Ratio of IC50 for human CYP2A6 to that of mouse CYP2A5 was determined [AID242975, Type: Literature]
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14
[SID103225480]
Antifungal activity against Microsporum gypseum C 115 by agar dilution method [AID376045, Type: Literature]
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15
[SID103225480]
Antifungal activity against Trichophyton mentagrophytes ATCC by agar dilution method [AID376046, Type: Literature]
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16
[SID103225480]
Antifungal activity against Trichophyton rubrum C 113 by agar dilution method [AID376047, Type: Literature]
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17
[SID103225480]
Antifungal activity against Epidermophyton floccosum C 114 by agar dilution method [AID376048, Type: Literature]
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18
[SID103225480]
Cytotoxicity against human THP1 cells assessed as cell viability at 1 uM after 24 hrs by CCK-8 assay relative to untreated control [AID767437, Type: Literature]
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19
[SID103225480]
Cytotoxicity against human THP1 cells assessed as cell viability at 10 uM after 24 hrs by CCK-8 assay relative to untreated control [AID767438, Type: Literature]
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20
[SID103225480]
Cytotoxicity against human THP1 cells assessed as cell viability at 50 uM after 24 hrs by CCK-8 assay relative to untreated control [AID767439, Type: Literature]
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