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Phenylalanine (CID 994) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(142)
 
 
Inconclusive(5)
 
 
Unspecified(25)
 
 
Top Targets:
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
 
NR LBD GR(4)
 
 
NR LBD TR(3)
 
 
NR LBD PPAR(2)
 
 
BioAssay Types:
Confirmatory(108)
 
 
 
Literature(27)
 
 
 
Summary(15)
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(62)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 171    Data Row: 173   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48416422]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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2
[SID103194122]
Km 740.5TP_TRANSPORTER: uptake in Xenopus laevis oocytes [AID681145, Type: Literature]SLC16A10 protein [gi:121945115]
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3
[SID103194122]
Km TP_TRANSPORTER: uptake in Xenopus laevis oocytes [AID681174, Type: Literature]Monocarboxylate transporter 8 [gi:81871342]
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4
[SID103194122]
Solubility assay expressed as [HbSdrug/HbS control] at 10 mM concentration [AID21129, Type: Literature]
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5
[SID103194122]
Solubility assay expressed as [HbSdrug/HbS control] at 20 mM concentration [AID21130, Type: Literature]
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6
[SID103194122]
Solubility assay expressed as [HbSdrug/HbS control] at 40 mM concentration [AID21131, Type: Literature]
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7
[SID103194122]
Solubility assay expressed as [HbSdrug/HbS control] at 5 mM concentration [AID21132, Type: Literature]
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8
[SID103194122]
Solubility of Deoxyhemoglobin S (dHbS) concentration after addition dithionite as control [AID21143, Type: Literature]
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9
[SID103194122]
Solubility of Haemoglobin S (HbS) concentration after addition of acid and dithionite [AID21145, Type: Literature]
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10
[SID103194122]
Solubility ratio ([HbS+drug (10 mM)]/[HbS-drug]) [AID22012, Type: Literature]
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11
[SID103194122]
Solubility ratio ([HbS+drug (20 mM)]/[HbS-drug] [AID22013, Type: Literature]
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12
[SID103194122]
Solubility ratio ([HbS+drug (40 mM)]/[HbS-drug]) [AID22148, Type: Literature]
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13
[SID103194122]
Solubility ratio ([HbS+drug (5 mM)]/[HbS-drug]) [AID22149, Type: Literature]
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14
[SID103194122]
Maximal activatory effect against human carbonic anhydrase II (hCA II) [AID47718, Type: Literature]
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15
[SID103194122]
Maximal activatory effect against human carbonic anhydrase I (hCA I) [AID50341, Type: Literature]
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16
[SID103194122]
Evaluated for antisickling activity, and initial HbS concentration was reported, values from different experiments (no. of runs=2) [AID85631, Type: Literature]
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17
[SID103194122]
Control value of dHbS(no. of runs=2) [AID85636, Type: Literature]
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18
[SID103194122]
Antigelling activity expressed as ratio of soluble sickle hemoglobin (HbS) of compound (g/dL) and that of control at 10 mM concentration. [AID91208, Type: Literature]
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19
[SID103194122]
Antigelling activity expressed as ratio of soluble sickle hemoglobin (HbS) of compound (g/dL) and that of control at 20 mM concentration. [AID91210, Type: Literature]
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20
[SID103194122]
Antigelling activity expressed as ratio of soluble sickle hemoglobin (HbS) of compound (g/dL) and that of control at 40 mM concentration [AID91211, Type: Literature]
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