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GW583373A (CID 9937660) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(3)
 
 
Inconclusive(3)
 
 
Top Targets:
PTKc HER2(1)
 
 
PTKc EGFR(1)
 
 
PTKc Src like(1)
 
 
Firefly Luc l..(1)
 
 
MPP superfami..(1)
 
 
BioAssay Types:
Literature(6)
 
 
Confirmatory(5)
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
IC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103498679]
IC50 0.012Inhibition of ErbB1 [AID270617, Type: Literature]Epidermal growth factor receptor [gi:2811086]
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2
[SID103498679]
IC50 0.023Inhibition of ErbB2 [AID270616, Type: Literature]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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3
[SID103498679]
IC50 0.32Inhibition of HN5 cell growth after 72 hrs [AID270618, Type: Literature]
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4
[SID124350082]
Potency 0.3675qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]tyrosine-protein kinase Yes [Homo sapiens] [gi:4885661]
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5
[SID103498679]
IC50 0.42Inhibition of BT474 cell growth after 72 hrs [AID270619, Type: Literature]
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6
[SID103498679]
IC50 0.46Inhibition of N87 cell growth after 72 hrs [AID270620, Type: Literature]
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7
[SID124350082]
Potency 0.0005qHTS Assay for Inhibitors of Sea Pansy Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652015, Type: confirmatory]Renilla-luciferin 2-monooxygenase (EC 1.13.12.5) - sea pansy (Renilla reniformis) (fragment) [gi:84399]
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8
[SID124350082]
Potency 1.9872qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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9
[SID124350082]
Potency qHTS for small molecule inhibitors of Yes1 kinase: Counter Assay [AID686950, Type: other]
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10
[SID124350082]
Potency 1.9872qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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11
[SID124350082]
Potency 14.5659qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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12
[SID124350082]
Potency 25.0176qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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