Bookmark and Share
GW0742 (CID 9934458) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(45)
 
 
Inactive(145)
 
 
Inconclusive(84)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(35)
 
 
 
 
 
NR LBD VDR(11)
 
 
 
 
NR LBD TR(11)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
 
BioAssay Types:
Confirmatory(202)
 
 
 
 
Literature(31)
 
 
 
 
 
Summary(24)
 
 
 
 
Screening(12)
 
 
 
BioActivity Types:
Potency(219)
 
 
 
 
EC50(11)
 
 
 
 
Kd(3)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 242    Data Row: 279   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103215363]
Kd 0.0004Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assay [AID731520, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
2
[SID103215363]
EC50 0.001Maximum transcriptional activation of human PPAR delta receptor [AID156617, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
3
[SID103215363]
IC50 0.001Binding affinity for human PPAR delta receptor [AID156625, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
4
[SID144212728]
Ratio Potency (uM) 0.001qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
5
[SID103215363]
EC50 0.0029Displacement of pan-PPAR fluormone from PPARdelta LBD by TR-FRET based LanthaScreen assay [AID675855, Type: Literature]
View
6
[SID103215363]
EC50 0.03Activity against murine PPAR delta receptor [AID156784, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:548577]
View
7
[SID103215363]
EC50 0.3Agonist activity at human PPARdelta LBD by cell based luciferase reporter gene assay [AID569828, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
8
[SID103215363]
EC50 0.92Displacement of pan-PPAR fluormone from PPARalpha LBD by TR-FRET based LanthaScreen assay [AID675854, Type: Literature]
View
9
[SID103215363]
EC50 1.1Maximum transcriptional activation of human PPAR alpha receptor [AID156147, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
10
[SID144212728]
Ratio Potency (uM) 1.1391qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
11
[SID26753244]
Potency 1.9953qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
12
[SID103215363]
EC50 2Maximum transcriptional activation of human PPAR gamma receptor [AID156945, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
View
13
[SID144212728]
Potency-Replicate_1 2.4541qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
14
[SID26753243]
Potency 7.9433qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
15
[SID103215363]
EC50 8.8Activity against murine PPAR alpha receptor [AID156452, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:1709728]
View
16
[SID26753243]
Potency 10qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
View
17
[SID144212728]
Potency-Replicate_1 12.2998qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
View
18
[SID26753243]
Potency 18.6548Cell Proliferation Assay Versus the ED40515 IL2 Dependent ATL cell lines [AID1053195, Type: confirmatory]
View
19
[SID29215130]
Potency 19.9526Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View
20
[SID144212728]
Potency-Replicate_1 21.8724qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
View