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Pentachlorophenol (CID 992) - Compound BioActivity Data
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BioActivity Outcomes:
Active(100)
 
 
Inactive(742)
 
 
Inconclusive(151)
 
 
Unspecified(48)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
 
7tm 4(26)
 
 
NR LBD AR(18)
 
 
 
NR LBD ER(18)
 
 
 
 
NR LBD TR(16)
 
 
 
 
BioAssay Types:
Confirmatory(510)
 
 
 
 
 
Screening(373)
 
 
 
 
Literature(64)
 
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(426)
 
 
 
 
 
IC50(16)
 
 
 
 
EC50(4)
 
 
 
 
Ki(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 816    Data Row: 1041   Total Pages: 53   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID53812556]
Ki 0.057Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain C, The Crystal Structure Of Nitrate Reductase A, Narghi, In Complex With The Q-Site Inhibitor Pentachlorophenol [gi:62738591]
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2
[SID53812556]
Ki 0.057Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain C, The Crystal Structure Of Nitrate Reductase A, Narghi, In Complex With The Q-Site Inhibitor Pentachlorophenol [gi:62738591]
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3
[SID47193736]
EC50 0.657Fluorescence Cell-Based Retest of C. albicans Growth in the Presence of Fluconazole [AID2467, Type: confirmatory]
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4
[SID144210343]
Potency-Replicate_1 1.532qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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5
[SID144210343]
Ratio Potency (uM) 2.08252qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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6
[SID47193736]
AbsAC1000_uM 2.888In vivo-based yeast HTS to detect compounds rescuing yeast growth/survival of Plasmodium Falciparum HSP40-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-01_Inhibitor_Dose_CherryPick_Activity [AID540271, Type: confirmatory]HSP40, subfamily A, putative [Plasmodium falciparum 3D7] [gi:124809271]
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7
[SID144209329]
Potency-Replicate_1 3.3678qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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8
[SID144209329]
Potency-Replicate_1 3.3678qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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9
[SID144209329]
Potency-Replicate_1 3.3979qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743191, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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10
[SID144210343]
Potency-Replicate_1 3.4297qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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11
[SID144209329]
Potency-Replicate_1 3.7788qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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12
[SID144210343]
Ratio Potency (uM) 3.84819qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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13
[SID144209329]
Ratio Potency (uM) 3.9266qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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14
[SID144209329]
Ratio Potency (uM) 4.57808qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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15
[SID144209329]
Ratio Potency (uM) 4.75718qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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16
[SID47193736]
Potency 8.1995A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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17
[SID144209329]
Potency-Replicate_1 8.4596qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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18
[SID144209329]
Potency-Replicate_1 8.5353qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID144209329]
TR Potency (uM) 8.79055qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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20
[SID47193736]
Potency 10qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen [AID720708, Type: confirmatory]Rap guanine nucleotide exchange factor 4 [gi:32171491]
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