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4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one (CID 9886808) - Compound BioActivity Data
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BioActivity Outcomes:
Active(10)
 
 
Inactive(129)
 
 
Unspecified(1)
 
 
Top Targets:
PKc like(15)
 
 
PKc(13)
 
 
 
PTKc Abl(7)
 
 
STKc AGC(5)
 
 
PTKc Kit(5)
 
 
 
BioAssay Types:
Confirmatory(139)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1    Data Row: 140   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50100092]
0.64Kinase Inhibitor Selectivity Profiling Assay [AID1433_27, Type: confirmatory]receptor-type tyrosine-protein kinase FLT3 [Homo sapiens] [gi:121114304]
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2
[SID50100092]
2Kinase Inhibitor Selectivity Profiling Assay [AID1433_196, Type: confirmatory]myosin light chain kinase 3 [Homo sapiens] [gi:146219832]
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3
[SID50100092]
3.1Kinase Inhibitor Selectivity Profiling Assay [AID1433_39, Type: confirmatory]mast/stem cell growth factor receptor Kit isoform 1 precursor [Homo sapiens] [gi:4557695]
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4
[SID50100092]
3.6Kinase Inhibitor Selectivity Profiling Assay [AID1433_30, Type: confirmatory]receptor-type tyrosine-protein kinase FLT3 [Homo sapiens] [gi:121114304]
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5
[SID50100092]
3.8Kinase Inhibitor Selectivity Profiling Assay [AID1433_56, Type: confirmatory]platelet-derived growth factor receptor beta precursor [Homo sapiens] [gi:4505683]
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6
[SID50100092]
4.8Kinase Inhibitor Selectivity Profiling Assay [AID1433_31, Type: confirmatory]receptor-type tyrosine-protein kinase FLT3 [Homo sapiens] [gi:121114304]
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7
[SID50100092]
5.2Kinase Inhibitor Selectivity Profiling Assay [AID1433_29, Type: confirmatory]receptor-type tyrosine-protein kinase FLT3 [Homo sapiens] [gi:121114304]
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8
[SID50100092]
6.1Kinase Inhibitor Selectivity Profiling Assay [AID1433_28, Type: confirmatory]receptor-type tyrosine-protein kinase FLT3 [Homo sapiens] [gi:121114304]
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9
[SID50100092]
7.2Kinase Inhibitor Selectivity Profiling Assay [AID1433_40, Type: confirmatory]mast/stem cell growth factor receptor Kit isoform 1 precursor [Homo sapiens] [gi:4557695]
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10
[SID50100092]
7.5Kinase Inhibitor Selectivity Profiling Assay [AID1433_36, Type: confirmatory]mast/stem cell growth factor receptor Kit isoform 1 precursor [Homo sapiens] [gi:4557695]
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11
[SID50100092]
Kinase Inhibitor Selectivity Profiling Assay [AID1433, Type: other]
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12
[SID50100092]
24Kinase Inhibitor Selectivity Profiling Assay [AID1433_166, Type: confirmatory]TRAF2 and NCK-interacting protein kinase isoform 1 [Homo sapiens] [gi:55741807]
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13
[SID50100092]
26Kinase Inhibitor Selectivity Profiling Assay [AID1433_38, Type: confirmatory]mast/stem cell growth factor receptor Kit isoform 1 precursor [Homo sapiens] [gi:4557695]
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14
[SID50100092]
44Kinase Inhibitor Selectivity Profiling Assay [AID1433_45, Type: confirmatory]mitogen-activated protein kinase kinase kinase kinase 1 isoform 1 [Homo sapiens] [gi:110611908]
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15
[SID50100092]
47Kinase Inhibitor Selectivity Profiling Assay [AID1433_60, Type: confirmatory]proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor [Homo sapiens] [gi:10862701]
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16
[SID50100092]
54Kinase Inhibitor Selectivity Profiling Assay [AID1433_55, Type: confirmatory]platelet-derived growth factor receptor alpha precursor [Homo sapiens] [gi:5453870]
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17
[SID50100092]
54Kinase Inhibitor Selectivity Profiling Assay [AID1433_203, Type: confirmatory]BMP-2-inducible protein kinase isoform b [Homo sapiens] [gi:38787904]
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18
[SID50100092]
60Kinase Inhibitor Selectivity Profiling Assay [AID1433_16, Type: confirmatory]macrophage colony-stimulating factor 1 receptor precursor [Homo sapiens] [gi:27262659]
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19
[SID50100092]
68Kinase Inhibitor Selectivity Profiling Assay [AID1433_71, Type: confirmatory]vascular endothelial growth factor receptor 2 precursor [Homo sapiens] [gi:11321597]
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20
[SID50100092]
69Kinase Inhibitor Selectivity Profiling Assay [AID1433_26, Type: confirmatory]vascular endothelial growth factor receptor 1 isoform 1 precursor [Homo sapiens] [gi:156104876]
View
21
[SID50100092]
71Kinase Inhibitor Selectivity Profiling Assay [AID1433_59, Type: confirmatory]proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor [Homo sapiens] [gi:10862701]
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22
[SID50100092]
79Kinase Inhibitor Selectivity Profiling Assay [AID1433_102, Type: confirmatory]ankyrin repeat and protein kinase domain-containing protein 1 [Homo sapiens] [gi:30425444]
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23
[SID50100092]
80Kinase Inhibitor Selectivity Profiling Assay [AID1433_242, Type: confirmatory]myosin light chain kinase family member 4 [Homo sapiens] [gi:167466233]
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24
[SID50100092]
92Kinase Inhibitor Selectivity Profiling Assay [AID1433_139, Type: confirmatory]myosin light chain kinase 2, skeletal/cardiac muscle [Homo sapiens] [gi:14993776]
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25
[SID50100092]
100Kinase Inhibitor Selectivity Profiling Assay [AID1433_68, Type: confirmatory]high affinity nerve growth factor receptor isoform 1 precursor [Homo sapiens] [gi:59889558]
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26
[SID50100092]
130Kinase Inhibitor Selectivity Profiling Assay [AID1433_199, Type: confirmatory]NUAK family SNF1-like kinase 2 [Homo sapiens] [gi:13569922]
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27
[SID50100092]
150Kinase Inhibitor Selectivity Profiling Assay [AID1433_84, Type: confirmatory]fibroblast growth factor receptor 1 isoform 3 precursor [Homo sapiens] [gi:13186234]
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28
[SID50100092]
160Kinase Inhibitor Selectivity Profiling Assay [AID1433_137, Type: confirmatory]mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] [gi:22035604]
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29
[SID50100092]
170Kinase Inhibitor Selectivity Profiling Assay [AID1433_200, Type: confirmatory]AP2-associated protein kinase 1 [Homo sapiens] [gi:148277037]
View
30
[SID50100092]
180Kinase Inhibitor Selectivity Profiling Assay [AID1433_231, Type: confirmatory]serine/threonine-protein kinase N1 isoform 1 [Homo sapiens] [gi:47132591]
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31
[SID50100092]
190Kinase Inhibitor Selectivity Profiling Assay [AID1433_74, Type: confirmatory]tyrosine-protein kinase Blk [Homo sapiens] [gi:33469982]
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32
[SID50100092]
190Kinase Inhibitor Selectivity Profiling Assay [AID1433_70, Type: confirmatory]receptor tyrosine kinase TrkC [Homo sapiens] [gi:442390]
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33
[SID50100092]
190Kinase Inhibitor Selectivity Profiling Assay [AID1433_86, Type: confirmatory]tyrosine-protein kinase Fgr [Homo sapiens] [gi:4885235]
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34
[SID50100092]
200Kinase Inhibitor Selectivity Profiling Assay [AID1433_52, Type: confirmatory]serine/threonine-protein kinase 4 [Homo sapiens] [gi:5454096]
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35
[SID50100092]
230Kinase Inhibitor Selectivity Profiling Assay [AID1433_208, Type: confirmatory]fibroblast growth factor receptor 3 isoform 1 precursor [Homo sapiens] [gi:4503711]
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36
[SID50100092]
240Kinase Inhibitor Selectivity Profiling Assay [AID1433_202, Type: confirmatory]NUAK family SNF1-like kinase 1 [Homo sapiens] [gi:7662170]
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37
[SID50100092]
250Kinase Inhibitor Selectivity Profiling Assay [AID1433_89, Type: confirmatory]tyrosine-protein kinase Lck precursor [Homo sapiens] [gi:112789546]
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38
[SID50100092]
250Kinase Inhibitor Selectivity Profiling Assay [AID1433_88, Type: confirmatory]eukaryotic translation initiation factor 2-alpha kinase 4 [Homo sapiens] [gi:65287717]
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39
[SID50100092]
260Kinase Inhibitor Selectivity Profiling Assay [AID1433_230, Type: confirmatory]phosphatidylinositol 5-phosphate 4-kinase type-2 beta [Homo sapiens] [gi:4505819]
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40
[SID50100092]
280Kinase Inhibitor Selectivity Profiling Assay [AID1433_4, Type: confirmatory]Aurora kinase B [Homo sapiens] [gi:127796234]
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41
[SID50100092]
290Kinase Inhibitor Selectivity Profiling Assay [AID1433_241, Type: confirmatory]serine kinase SRPK2 [Homo sapiens] [gi:1857944]
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42
[SID50100092]
300Kinase Inhibitor Selectivity Profiling Assay [AID1433_64, Type: confirmatory]STE20-like serine/threonine-protein kinase [Homo sapiens] [gi:41281453]
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43
[SID50100092]
310Kinase Inhibitor Selectivity Profiling Assay [AID1433_236, Type: confirmatory]ribosomal protein S6 kinase alpha-2 isoform a [Homo sapiens] [gi:19923570]
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44
[SID50100092]
320Kinase Inhibitor Selectivity Profiling Assay [AID1433_61, Type: confirmatory]receptor-interacting serine/threonine-protein kinase 1 [Homo sapiens] [gi:57242761]
View
45
[SID50100092]
350Kinase Inhibitor Selectivity Profiling Assay [AID1433_194, Type: confirmatory]glycogen synthase kinase-3 beta isoform 1 [Homo sapiens] [gi:21361340]
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46
[SID50100092]
350Kinase Inhibitor Selectivity Profiling Assay [AID1433_178, Type: confirmatory]dual specificity mitogen-activated protein kinase kinase 2 [Homo sapiens] [gi:13489054]
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47
[SID50100092]
370Kinase Inhibitor Selectivity Profiling Assay [AID1433_209, Type: confirmatory]fibroblast growth factor receptor 3 isoform 1 precursor [Homo sapiens] [gi:4503711]
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48
[SID50100092]
380Kinase Inhibitor Selectivity Profiling Assay [AID1433_211, Type: confirmatory]tyrosine-protein kinase JAK1 [Homo sapiens] [gi:102469034]
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49
[SID50100092]
410Kinase Inhibitor Selectivity Profiling Assay [AID1433_128, Type: confirmatory]fibroblast growth factor receptor 2 isoform 2 precursor [Homo sapiens] [gi:189083817]
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50
[SID50100092]
420Kinase Inhibitor Selectivity Profiling Assay [AID1433_233, Type: confirmatory]serine/threonine-protein kinase RIO1 isoform 1 [Homo sapiens] [gi:23510356]
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