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Cyproterone Acetate (CID 9880) - Compound BioActivity Data
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BioActivity Outcomes:
Active(97)
 
 
Inactive(1240)
 
 
Inconclusive(202)
 
 
Unspecified(411)
 
 
Top Targets:
7TM GPCR Srx(53)
 
 
 
 
 
7TM GPCR Srsx(47)
 
 
 
 
NR LBD PPAR(34)
 
 
 
NR LBD AR(28)
 
 
 
 
 
NR LBD ER(28)
 
 
 
 
 
BioAssay Types:
Confirmatory(785)
 
 
 
 
 
Screening(650)
 
 
 
Literature(135)
 
 
 
 
 
Summary(72)
 
 
 
 
BioActivity Types:
Potency(655)
 
 
 
 
 
IC50(154)
 
 
 
 
Ki(5)
 
 
EC50(4)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1196    Data Row: 1950   Total Pages: 98   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103382993]
Ki 0.00076Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand. [AID32025, Type: Literature]
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2
[SID103382993]
Ki 0.0013Adenosine A1 receptor binding was measured in adenosine deaminase (ADA) pretreated rat cortical membranes using [3H]cyclohexyladenosine in the presence of 2-chloroadenosine [AID31717, Type: Literature]
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3
[SID103382993]
IC50 0.005Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes without GTP [AID31540, Type: Literature]Adenosine receptor A1 [gi:2827766]
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4
[SID103382993]
Ki 0.014Binding affinity for human androgen receptor in transiently-transfected COS-1 cells. [AID39147, Type: Literature]
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5
[SID103382993]
IC50 0.023Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells. [AID38975, Type: Literature]
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6
[SID103382993]
IC50 0.037DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) [AID625172, Type: confirmatory]Progesterone receptor [gi:75071465]
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7
[SID103382993]
IC50 0.047DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: confirmatory]Androgen receptor [gi:113832]
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8
[SID144208884]
Potency-Replicate_1 0.0616qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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9
[SID103382993]
IC50 0.125Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes with GTP [AID31541, Type: Literature]Adenosine receptor A1 [gi:2827766]
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10
[SID103382993]
IC50 0.225DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) [AID625263, Type: confirmatory]Glucocorticoid receptor [gi:121069]
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11
[SID103382993]
Ki 0.336Binding affinity against adenosine A2 receptor from rat striatum using [3H]NECA as radioligand. [AID33574, Type: Literature]
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12
[SID103382993]
IC50 0.63096Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881) [AID255211, Type: Literature]
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13
[SID103382993]
Ki 0.636Binding to Adenosine A2 receptor was measured in ADA-pretreated rat striatal membranes using [3H]-CGS- 21680 [AID33592, Type: Literature]
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14
[SID144208884]
Potency-Replicate_1 0.9679qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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15
[SID144213258]
Ratio Potency (uM) 1.05507qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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16
[SID144213258]
Ratio Potency (uM) 1.27825qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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17
[SID144204615]
Potency-Replicate_1 1.5089qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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18
[SID144204615]
Ratio Potency (uM) 1.5089qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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19
[SID144208884]
Ratio Potency (uM) 1.54788qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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20
[SID144208884]
Potency-Replicate_1 1.7367qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View