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3-Cl-AHPC (CID 9866186) - Compound BioActivity Data
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BioActivity Outcomes:
Active(34)
 
 
Inactive(4)
 
 
Inconclusive(4)
 
 
Unspecified(78)
 
 
Top Targets:
NR LBD SHP(4)
 
 
 
PTPc(1)
 
 
STKc IKK beta(1)
 
 
UBL TBK1 like(1)
 
 
STKc IKK alph..(1)
 
 
BioAssay Types:
Literature(120)
 
 
 
 
 
BioActivity Types:
IC50(22)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 120    Data Row: 120   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103437115]
IC50 0.047Antiproliferative activity against mouse MMTV-Wnt-1 cells assessed as cell viability after 72 hrs by DAPI staining method [AID646009, Type: Literature]
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2
[SID103437115]
IC50 0.16Antiproliferative activity against human MOLT4 cells assessed as cell viability after 72 hrs by luciferase assay [AID646005, Type: Literature]
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3
[SID103437115]
IC50 0.17Antiproliferative activity against human OCI-AML2 cells assessed as cell viability after 72 hrs by luciferase assay [AID646004, Type: Literature]
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4
[SID103437115]
IC50 0.2Concentration of compound required for inhibition of (NB4) human promyelocytic leukemia cell growth by 50% [AID248352, Type: Literature]
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5
[SID103437115]
IC50 0.281Induction of apoptosis in mouse MMTV-Wnt-1 cells assessed as cell viability after 72 hrs by DAPI staining based cell counting [AID610164, Type: Literature]
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6
[SID103437115]
IC50 0.3Antiproliferative activity against HMVE cells [AID288576, Type: Literature]
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7
[SID103437115]
IC50 0.3Growth inhibition of primary HMVE cells after 72 hrs [AID288596, Type: Literature]
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8
[SID103437115]
IC50 0.3Inhibition of cell proliferation in retinoid-resistant KG1 cells after 48 hrs [AID288590, Type: Literature]
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9
[SID103437115]
IC50 0.4Growth inhibition of retinoid-resistant H292 cells after 72 hrs [AID288586, Type: Literature]
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10
[SID103437115]
IC50 0.4Antiproliferative activity against human H292 cells after 72 hrs by MTT assay [AID365048, Type: Literature]
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11
[SID103437115]
IC50 0.48Antiproliferative activity against human DU145 cells after 72 hrs by MTT assay [AID365046, Type: Literature]
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12
[SID103437115]
IC50 0.5Growth inhibition of retinoid-resistant DU145 cells after 72 hrs [AID288588, Type: Literature]
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13
[SID103437115]
IC50 0.54Antiproliferative activity against human K562 cells assessed as cell viability after 72 hrs by luciferase assay [AID646003, Type: Literature]
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14
[SID103437115]
IC50 0.58Concentration of compound required for inhibition of (IGROV-1) human ovarian carcinoma cell growth by 50% [AID248330, Type: Literature]
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15
[SID103437115]
IC50 0.73Concentration of compound required for inhibition of (IGROV-1/Pt1) human cisplatin resistant ovarian carcinoma cell growth by 50% [AID248756, Type: Literature]
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16
[SID103437115]
IC50 0.95Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay [AID365047, Type: Literature]
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17
[SID103437115]
IC50 1.4Antiproliferative activity against human KG1 AML cells after 48 hrs by MTT assay [AID365045, Type: Literature]
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18
[SID103437115]
IC50 1.8Growth inhibition of retinoid-resistant MDA-MB-231 cells after 72 hrs [AID288584, Type: Literature]
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19
[SID103437115]
IC50 2.1Inhibition of SHP2 overexpressed in human KG1 cells [AID364175, Type: Literature]Tyrosine-protein phosphatase non-receptor type 11 [gi:84028248]
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20
[SID103437115]
IC50 2.5Displacement of [5,5'-3H2]AHPN from human recombinant GST-SHP by liquid scintillation counting relative to 3-Cl-AHPC [AID364173, Type: Literature]Nuclear receptor subfamily 0 group B member 2 [gi:9978744]
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