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Metaproterenol (CID 9861452) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(568)
 
 
Inconclusive(22)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(19)
 
 
 
G-alpha(7)
 
 
 
Tryp SPc(7)
 
 
 
RGS RGS4(7)
 
 
 
BioAssay Types:
Screening(398)
 
 
 
 
Confirmatory(182)
 
 
 
 
Literature(8)
 
 
 
BioActivity Types:
Potency(133)
 
 
 
 
IC50(36)
 
 
EC50(7)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 552    Data Row: 604   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26732609]
Counterscreen for antagonists of the galanin Receptor 3 (GalR3): Fluorescence-based cell-based high throughput screening assay to identify non specific agonists of the parental HEK-CNG cells [AID652268, Type: screening]
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2
[SID26732609]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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3
[SID26732609]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]galanin receptor type 3 [Homo sapiens] [gi:4503907]
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4
[SID26732609]
Fluorescence-based cell-based primary high throughput confirmation assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID652245, Type: screening]galanin receptor type 3 [Homo sapiens] [gi:4503907]
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5
[SID26732609]
Primary cell-based high-throughput screening assay for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4) [AID463165, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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6
[SID26732609]
Validation assay for identification of compounds that inhibit the regulator of G-protein signaling 4 (RGS4) [AID492999, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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7
[SID26732609]
Counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay [AID493000, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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8
[SID26732609]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Secondary Assay 3 with KCC2 cells [AID1714, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
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9
[SID26732609]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Primary Screen [AID1456, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
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10
[SID26732609]
Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [AID940, Type: screening]prostaglandin E2 receptor EP2 subtype [Homo sapiens] [gi:31881630]
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11
[SID103770795]
Beta-2 adrenergic receptor agonist [AID742548, Type: other]Beta-2 adrenergic receptor [gi:296439450]
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12
[SID26732609]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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13
[SID103770795]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
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14
[SID103770795]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
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15
[SID26732609]
Potency 8.9125qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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16
[SID26732609]
Potency 15.8489qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
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17
[SID26732609]
Potency 20.7865Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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18
[SID26732609]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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19
[SID26732609]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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20
[SID103770795]
Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay [AID521220, Type: Literature]
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21
[SID26732609]
qHTS Assay for Inhibitors of the Six1/Eya2 Interaction [AID651725, Type: screening]six1 [Homo sapiens] [gi:1246761]
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22
[SID26732609]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ MEP2_MLPCN. [AID2016, Type: screening]MEP2 [Saccharomyces cerevisiae] [gi:1302091]
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23
[SID26732609]
uHTS for Calpain Inhibitors [AID1236, Type: screening]calpain II, partial [Sus scrofa] [gi:1628587]
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24
[SID26732609]
Potency qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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25
[SID26732609]
uHTS identification of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay [AID651560, Type: screening]Low molecular weight phosphotyrosine protein phosphatase [gi:1709543]
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26
[SID26732609]
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate regulator of G-protein signaling 4 (RGS4) [AID463111, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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27
[SID26732609]
Second counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay without carbachol activation [AID493001, Type: screening]regulator of G-protein signaling 4 isoform 2 [Homo sapiens] [gi:5032039]
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28
[SID26732609]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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29
[SID26732609]
Counterscreen for PME1 inhibitors: fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of lysophospholipase 1 (LYPLA1). [AID2174, Type: screening]acyl-protein thioesterase 1 isoform 1 [Homo sapiens] [gi:5453722]
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30
[SID26732609]
Potency qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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31
[SID26732609]
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity [AID623870, Type: screening]transforming acidic coiled-coil-containing protein 3 [Homo sapiens] [gi:5454102]
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32
[SID26732609]
Potency qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101 [AID493005, Type: confirmatory]tumor susceptibility gene 101 protein [Homo sapiens] [gi:5454140]
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33
[SID26732609]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2) [AID651957, Type: screening]nuclear receptor coactivator 2 [Homo sapiens] [gi:5729858]
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34
[SID26732609]
Potency qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
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35
[SID26732609]
uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]C-X-C chemokine receptor type 6 [Homo sapiens] [gi:5730106]
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36
[SID26732609]
uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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37
[SID26732609]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 6 (SENP6) [AID2599, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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38
[SID26732609]
Fluorescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of the Ras-converting Enzyme [AID2563, Type: screening]Rce1p [Saccharomyces cerevisiae S288c] [gi:6323930]
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39
[SID26732609]
HTS of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin [AID504577, Type: screening]Vma11p [Saccharomyces cerevisiae S288c] [gi:6325022]
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40
[SID26732609]
Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
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41
[SID26732609]
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 [AID1672, Type: screening]inward rectifier potassium channel 2 [Mus musculus] [gi:6680530]
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42
[SID26732609]
Potency qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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43
[SID26732609]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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44
[SID26732609]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex [AID504707, Type: screening]cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] [gi:6755076]
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45
[SID26732609]
Kallikrein 5 1536 HTS [AID873, Type: screening]kallikrein-5 preproprotein [Homo sapiens] [gi:6912644]
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46
[SID26732609]
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity [AID504441, Type: screening]dual specificity tyrosine-phosphorylation-regulated kinase 1A [Rattus norvegicus] [gi:6978787]
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47
[SID26732609]
Potency qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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48
[SID26732609]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624037, Type: screening]muscarinic acetylcholine receptor M5 [Homo sapiens] [gi:7108336]
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49
[SID26732609]
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624038, Type: screening]muscarinic acetylcholine receptor M5 [Homo sapiens] [gi:7108336]
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50
[SID26732609]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]muscarinic acetylcholine receptor M5 [Homo sapiens] [gi:7108336]
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