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Palmitic Acid (CID 985) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(369)
 
 
Inconclusive(59)
 
 
Unspecified(69)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD ER(23)
 
 
 
 
NR LBD VDR(15)
 
 
 
NR LBD Fxr(14)
 
 
 
BioAssay Types:
Confirmatory(254)
 
 
 
 
Literature(149)
 
 
 
 
 
Summary(72)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(305)
 
 
 
 
IC50(9)
 
 
 
Ki(4)
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 266    Data Row: 510   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103287192]
Ki 0.336Displacement of 1,8-ANS from aFABP by fluorescence based-assay [AID307907, Type: Literature]
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2
[SID144205658]
Potency-Replicate_1 0.6682qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID103287192]
Ki 0.802Displacement of 1,8-ANS from eFABP by fluorescence based-assay [AID307909, Type: Literature]
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4
[SID103287192]
IC50 0.93In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) [AID241812, Type: Literature]Fatty acid-binding protein, adipocyte [gi:119781]
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5
[SID103287192]
IC50 1.2In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP) [AID241834, Type: Literature]Fatty acid-binding protein, epidermal [gi:232081]
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6
[SID103287192]
IC50 1.7In vitro inhibitory concentration against intestinal fatty acid binding protein(I-FABP) [AID241835, Type: Literature]Fatty acid-binding protein, intestinal [gi:119805]
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7
[SID26757777]
Potency 2.5119qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID103287192]
IC50 2.6In vitro inhibitory concentration against heart and muscle fatty acid binding protein(H-FABP) [AID242001, Type: Literature]Fatty acid-binding protein, heart [gi:119802]
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9
[SID103287192]
IC50 5Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cells [AID261940, Type: Literature]Toll-like receptor 2 [gi:20140434]
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10
[SID144205658]
Potency-Replicate_1 11.8832qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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11
[SID144205658]
Ratio Potency (uM) 15.0742qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID144205658]
Potency-Replicate_1 15.089qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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13
[SID103287192]
Ki Binding affinity to human kFABP [AID268957, Type: Literature]Fatty acid-binding protein, epidermal [gi:232081]
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14
[SID103287192]
Kd 83Binding affinity against Adipocyte lipid binding protein [AID32788, Type: Literature]
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15
[SID103287192]
IC50 209Cytotoxicity against rat L6 cells [AID690546, Type: Literature]
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16
[SID103287192]
MIC 400Antimicrobial activity against Staphylococcus aureus ATCC 25923 after overnight incubation [AID361446, Type: Literature]
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17
[SID103287192]
MIC 400Antimicrobial activity against Streptococcus faecalis ATCC 29212 after overnight incubation [AID361447, Type: Literature]
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18
[SID103287192]
MIC 400Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after overnight incubation [AID361448, Type: Literature]
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19
[SID103287192]
MIC 400Antimicrobial activity against Escherichia coli ATCC 25922 after overnight incubation [AID361449, Type: Literature]
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20
[SID103287192]
IC50 500Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acid [AID360927, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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21
[SID103287192]
IC50 500Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acid [AID360928, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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22
[SID103287192]
IC50 5800Binding affinity to Vibrio cholerae cholera toxin assessed as inhibition of cholera toxin binding to ganglioside GM1 receptor treated 15 mins before receptor addition by ELISA [AID423126, Type: Literature]
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23
[SID103287192]
Cytotoxicity against african green monkey Vero cells upto 50 uM by neutral red assay [AID426207, Type: Literature]
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24
[SID103287192]
Cytotoxicity against pig LLC-PK11 cells upto 50 uM by neutral red assay [AID426208, Type: Literature]
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25
[SID103287192]
Cytotoxicity against human SW1353 cells by neutral red assay [AID426210, Type: Literature]
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26
[SID103287192]
Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined at 2 x 10E-4 M [AID40631, Type: Literature]
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27
[SID103287192]
Binding affinity against Fatty acid-binding protein [AID71607, Type: Literature]
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28
[SID103287192]
Antimicrobial activity against Neisseria meningitidis M7 by agar dilution method [AID498873, Type: Literature]
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29
[SID103287192]
Antimicrobial activity against Neisseria meningitidis M7tolC::Kan by agar dilution method [AID498874, Type: Literature]
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30
[SID103287192]
Antimicrobial activity against Neisseria meningitidis M7mtrE::Spc by agar dilution method [AID498875, Type: Literature]
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31
[SID103287192]
Antimicrobial activity against Neisseria meningitidis M7tolC::Kan mtr::Spc by agar dilution method [AID498876, Type: Literature]
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32
[SID103287192]
Antimalarial activity against erythrocytic stages of chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 assessed as [3H]hypoxanthine incorporation after 48 hrs by liquid scintillation counting [AID527262, Type: Literature]
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33
[SID103287192]
Antimalarial activity against liver stages of Plasmodium yoelii expressing GFP infected in human HepG2:CD81 cells after 43 hrs by flow cytometry [AID527263, Type: Literature]
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34
[SID103287192]
Antimalarial activity against liver stages of Plasmodium yoelii expressing GFP infected in human HepG2:CD81 cells after 43 hrs by immunofluorescence analysis [AID527264, Type: Literature]
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35
[SID103287192]
Inhibition of Plasmodium falciparum FabI by spectrophotometric analysis [AID527266, Type: Literature]
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36
[SID103287192]
Trypanocidal activity against bloodstream form of Trypanosoma brucei rhodesiense STIB 900 after 72 hrs [AID527276, Type: Literature]
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37
[SID103287192]
Trypanocidal activity against intracellular amastigotes of Trypanosoma cruzi Tulahuen C2C4 expressing LacZ gene infected in rat L6 cells after 96 hrs [AID527277, Type: Literature]
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38
[SID103287192]
Leishmanicidal activity against axenic amastigotes of Leishmania donovani MHOM/ET/67/L82 after 72 hrs [AID527278, Type: Literature]
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39
[SID103287192]
Cytotoxicity against rat L6 cells after 72 hrs by microplate fluorometric analysis [AID527279, Type: Literature]
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40
[SID103287192]
Antibacterial activity against Staphylococcus aureus by broth microdilution method [AID597407, Type: Literature]
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41
[SID103287192]
Antibacterial activity against methicillin-resistant Staphylococcus aureus by broth microdilution method [AID597408, Type: Literature]
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42
[SID103287192]
Antibacterial activity against Mycobacterium smegmatis mc2 155 after 72 hrs by MTT assay [AID658437, Type: Literature]
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43
[SID103287192]
Inhibition of Multidrug resistance efflux pump in Mycobacterium smegmatis mc2 155 assessed as modulation of EtBr-mediated antibacterial activity measuring ratio of EtBr MIC to EtBr and compound MIC at 64 mg/L after 72 hrs by MTT assay [AID658438, Type: Literature]
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44
[SID103287192]
Antibacterial activity against Bacillus subtilis ATCC 6633 after 48 hrs by silica gel plate-based INT-formazan method [AID337692, Type: Literature]
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45
[SID103287192]
Antibacterial activity against Escherichia coli ATCC 25922 after 48 hrs by silica gel plate-based INT-formazan method [AID337693, Type: Literature]
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46
[SID103287192]
Biodistribution in rat blood after 1 hr of intravenous injection at a dose of 140-160 g [AID18491, Type: Literature]
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47
[SID103287192]
Biodistribution in rat blood after 10 min of intravenous injection at a dose of 140-160 g [AID18492, Type: Literature]
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48
[SID103287192]
Biodistribution in rat blood after 15 min of intravenous injection at a dose of 140-160 g [AID18493, Type: Literature]
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49
[SID103287192]
Biodistribution in rat blood after 30 min of intravenous injection at a dose of 140-160 g [AID18494, Type: Literature]
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50
[SID103287192]
Biodistribution in rat blood after 5 min of intravenous injection at a dose of 140-160 g [AID18495, Type: Literature]
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