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Palmitic Acid (CID 985) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(389)
 
 
Inconclusive(40)
 
 
Unspecified(70)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
NR LBD ER(23)
 
 
 
 
NR LBD AR(23)
 
 
 
NR LBD VDR(15)
 
 
 
NR LBD GR(14)
 
 
 
BioAssay Types:
Confirmatory(255)
 
 
 
 
Literature(153)
 
 
 
 
 
Summary(72)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(306)
 
 
 
 
IC50(9)
 
 
 
Ki(4)
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 270    Data Row: 514   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103287192]
Ki 0.336Displacement of 1,8-ANS from aFABP by fluorescence based-assay [AID307907, Type: Literature]
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2
[SID144205658]
Potency-Replicate_1 0.6682qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID103287192]
Ki 0.802Displacement of 1,8-ANS from eFABP by fluorescence based-assay [AID307909, Type: Literature]
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4
[SID103287192]
IC50 0.93In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP) [AID241812, Type: Literature]Fatty acid-binding protein, adipocyte [gi:119781]
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5
[SID103287192]
IC50 1.2In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP) [AID241834, Type: Literature]Fatty acid-binding protein, epidermal [gi:232081]
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6
[SID103287192]
IC50 1.7In vitro inhibitory concentration against intestinal fatty acid binding protein(I-FABP) [AID241835, Type: Literature]Fatty acid-binding protein, intestinal [gi:119805]
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7
[SID26757777]
Potency 2.5119qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID103287192]
IC50 2.6In vitro inhibitory concentration against heart and muscle fatty acid binding protein(H-FABP) [AID242001, Type: Literature]Fatty acid-binding protein, heart [gi:119802]
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9
[SID103287192]
IC50 5Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cells [AID261940, Type: Literature]Toll-like receptor 2 [gi:20140434]
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10
[SID144205658]
Potency-Replicate_1 11.8832qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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11
[SID144205658]
Ratio Potency (uM) 15.0742qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID144205658]
Potency-Replicate_1 15.089qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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13
[SID103287192]
Ki Binding affinity to human kFABP [AID268957, Type: Literature]Fatty acid-binding protein, epidermal [gi:232081]
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14
[SID103287192]
Inhibition of osteoclastogenesis in CD1 mouse bone marrow cells at 5 ug/ml added on day 2 and day 4 measured on day 7 by TRAP assay relative to GW9508 [AID756258, Type: Literature]
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15
[SID103287192]
Inhibition of osteoclastogenesis in CD1 mouse bone marrow cells at 0.1 to 10 ug/ml added on day 2 and day 4 measured on day 7 by TRAP assay [AID756259, Type: Literature]
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16
[SID103287192]
Kd 83Binding affinity against Adipocyte lipid binding protein [AID32788, Type: Literature]
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17
[SID103287192]
IC50 209Cytotoxicity against rat L6 cells [AID690546, Type: Literature]
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18
[SID103287192]
IC50 500Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acid [AID360927, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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19
[SID103287192]
IC50 500Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acid [AID360928, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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20
[SID103287192]
IC50 5800Binding affinity to Vibrio cholerae cholera toxin assessed as inhibition of cholera toxin binding to ganglioside GM1 receptor treated 15 mins before receptor addition by ELISA [AID423126, Type: Literature]
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