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N-(5-adamantane-1-yl-methoxy-pentyl)deoxynojirimycin (CID 9822159) - Compound BioActivity Data
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BioActivity Outcomes:
Active(44)
 
 
Unspecified(13)
 
 
Top Targets:
Glucosylceram..(4)
 
 
DUF608(2)
 
 
GH31 MGAM SI..(2)
 
 
GH31(1)
 
 
Glyco hydro 3..(1)
 
 
BioAssay Types:
Literature(57)
 
 
 
BioActivity Types:
IC50(30)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 57    Data Row: 57   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103698575]
IC50 0.0003Inhibition of non-lysosomal glucosylceramidase in cultured melanoma cells [AID700851, Type: Literature]
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2
[SID103698575]
IC50 0.001Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysis [AID652573, Type: Literature]Non-lysosomal glucosylceramidase [gi:143018392]
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3
[SID103698575]
IC50 0.001Inhibition of human GBA2 [AID437994, Type: Literature]Non-lysosomal glucosylceramidase [gi:143018392]
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4
[SID103698575]
IC50 0.001Inhibition of GBA2 by HPLC [AID466671, Type: Literature]
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5
[SID103698575]
IC50 0.001Inhibition of recombinant GBA2 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assay [AID553254, Type: Literature]
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6
[SID103698575]
IC50 0.002Inhibition of non-lysosomal glucosylceramidase [AID700852, Type: Literature]
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7
[SID103698575]
IC50 0.09Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysis [AID699203, Type: Literature]
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8
[SID103698575]
IC50 0.09Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reaction [AID626355, Type: Literature]
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9
[SID103698575]
IC50 0.13Inhibition of rice alpha glucosidase [AID437996, Type: Literature]
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10
[SID103698575]
IC50 0.15Inhibition of GCS by cell-based assay [AID466666, Type: Literature]
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11
[SID103698575]
IC50 0.2Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence scanner [AID652571, Type: Literature]Ceramide glucosyltransferase [gi:38257364]
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12
[SID103698575]
IC50 0.2Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assay [AID553252, Type: Literature]Ceramide glucosyltransferase [gi:38257364]
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13
[SID103698575]
IC50 0.2Inhibition of recombinant GBA1 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assay [AID553253, Type: Literature]
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14
[SID103698575]
IC50 0.2Inhibition of recombinant glucosylceramidase 1 using 4-methylumbelliferyl-B-glucoside as substrate by fluorimetric analysis [AID652572, Type: Literature]
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15
[SID103698575]
IC50 0.2Inhibition of GBA1 by HPLC [AID466670, Type: Literature]
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16
[SID103698575]
IC50 0.2Inhibition of human GBA1 [AID437993, Type: Literature]
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17
[SID103698575]
IC50 0.4Inhibition of lysosomal alpha-glucosidase by HPLC [AID466672, Type: Literature]
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18
[SID103698575]
IC50 0.4Inhibition of human lysosomal alpha glucosidase [AID437995, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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19
[SID103698575]
IC50 0.5Inhibition of sucrase in mouse intestinal input by glucose release assay [AID553255, Type: Literature]Sucrase-isomaltase, intestinal [Cricetulus griseus] [gi:344247361]
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20
[SID103698575]
IC50 0.5Inhibition of sucrase by HPLC [AID466667, Type: Literature]
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